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Neuroscience

D-Index
68
Citations
12980
World Ranking
2804
National Ranking
73

Research.com Recognitions

  • 1959 - Fellow of Alfred P. Sloan Foundation

Overview

Paul Franken is affiliated with the University of Lausanne in Switzerland and focuses primarily on neuroscience. Their research explores various dimensions of sleep and circadian rhythms, concentrating on interconnected processes that regulate homeostasis and behavior.

The most recent work highlights key topics such as sleep and wakefulness rhythms, circadian biology, and the effects of light on physiology. Important publications include:

  • Sleep and circadian rhythmicity as entangled processes serving homeostasis (2023) in Nature reviews. Neuroscience
  • Rapid fast-delta decay following prolonged wakefulness marks a phase of wake-inertia in NREM sleep (2020) in Nature Communications
  • Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocks (2021) in Genes & Development
  • The sleep-wake distribution contributes to the peripheral rhythms in PERIOD-2 (2021) in eLife
  • Dissecting and modeling photic and melanopsin effects to predict sleep disturbances induced by irregular light exposure in mice (2021) in Proceedings of the National Academy of Sciences

Frequent coauthors collaborating with Paul Franken are:

  • Yann Emmenegger
  • Maxime Jan
  • Jeffrey Hubbard
  • Marieke MB Hoekstra
  • Charlotte N. Hor

The primary venues for their publications include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • eLife
  • Zenodo (CERN European Organization for Nuclear Research)

Paul Franken's work spans the main field of neuroscience, with significant engagement in the following subfields:

  • Endocrine and Autonomic Systems
  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology
  • Cellular and Molecular Neuroscience
  • Molecular Biology

Their research addresses several core topics:

  • Sleep and Wakefulness Research
  • Circadian rhythm and melatonin
  • Sleep and related disorders
  • Photoreceptor and optogenetics research
  • Neuroscience of respiration and sleep
  • Spaceflight effects on biology
  • Light effects on plants

Paul Franken has been recognized as a Fellow of the Alfred P. Sloan Foundation since 1959.

Best Publications

  • Role of Melanopsin in Circadian Responses to Light

    Norman F. Ruby;Thomas J. Brennan;Xinmin Xie;Vinh Cao

  • The Homeostatic Regulation of Sleep Need Is under Genetic Control

    Paul Franken;Didier Chollet;Mehdi Tafti

  • Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature.

    P. Franken;Derk-Jan Dijk;I. Tobler;A. A. Borbely

  • Altered Patterns of Sleep and Behavioral Adaptability in NPAS2-Deficient Mice

    Carol A. Dudley;Claudia Erbel-Sieler;Sandi Jo Estill;Martin Reick

  • Homer1a is a core brain molecular correlate of sleep loss

    Stéphanie Maret;Stéphane Dorsaz;Laure Gurcel;Sylvain Pradervand

  • Circadian clock genes and sleep homeostasis.

    P. Franken;D.-J. Dijk

  • Genetic variation in EEG activity during sleep in inbred mice

    Paul Franken;Alain Malafosse;Mehdi Tafti

  • Genetic determinants of sleep regulation in inbred mice.

    Paul Franken;Alain Malafosse;Mehdi Tafti

  • A role for cryptochromes in sleep regulation.

    Jonathan P Wisor;Bruce F O'Hara;Akira Terao;Chris P Selby

  • Clock-Talk: Interactions between central and peripheral circadian oscillators in mammals

    Ueli Schibler;Ivana Gotic;Camille Saini;Pascal Gos

  • Melanopsin as a Sleep Modulator: Circadian Gating of the Direct Effects of Light on Sleep and Altered Sleep Homeostasis in Opn4−/− Mice

    Jessica W. Tsai;Jens Hannibal;Grace Hagiwara;Damien Colas

  • T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites

    Lucius Cueni;Marco Canepari;Rafael Luján;Yann Emmenegger

  • The Ca(V)3.3 calcium channel is the major sleep spindle pacemaker in thalamus.

    Simone Astori;Ralf D. Wimmer;Haydn M. Prosser;Haydn M. Prosser;Corrado Corti

  • Sleep homeostasis in the rat: simulation of the time course of EEG slow-wave activity.

    Paul Franken;Irene Tobler;Alexander A. Borbély

  • Key Electrophysiological, Molecular, and Metabolic Signatures of Sleep and Wakefulness Revealed in Primary Cortical Cultures

    Valérie Hinard;Cyril Mikhail;Sylvain Pradervand;Thomas Curie

  • NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: Genotype and sex interactions

    Paul Franken;Carol A. Dudley;Sandi Jo Estill;Monique Barakat

  • Separating the Contribution of Glucocorticoids and Wakefulness to the Molecular and Electrophysiological Correlates of Sleep Homeostasis

    Valérie Mongrain;Susana A. Hernandez;Sylvain Pradervand;Stéphane Dorsaz

  • Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions.

    Deanna M. Arble;Joseph Bass;Cecilia Diniz Behn;Matthew P. Butler

  • A non-circadian role for clock-genes in sleep homeostasis:a strain comparison

    Paul Franken;Paul Franken;Ryan Thomason;H Craig Heller;Bruce F O'Hara

  • Real-time recording of circadian liver gene expression in freely moving mice reveals the phase-setting behavior of hepatocyte clocks

    Camille Saini;André Liani;Thomas Curie;Pascal Gos

  • GENETICS OF SLEEP AND SLEEP DISORDERS

    Paul Franken;Mehdi Tafti

Frequent Co-Authors

Mehdi Tafti
Mehdi Tafti University of Lausanne
Irene Tobler
Irene Tobler University of Zurich
Bruce F. O'Hara
Bruce F. O'Hara University of Kentucky
Alexander A. Borbély
Alexander A. Borbély University of Zurich
H. Craig Heller
H. Craig Heller Stanford University
Anita Lüthi
Anita Lüthi University of Lausanne
Hans-Peter Landolt
Hans-Peter Landolt University of Zurich
Derk-Jan Dijk
Derk-Jan Dijk University of Surrey
Yves Dauvilliers
Yves Dauvilliers University of Montpellier
Thomas S. Kilduff
Thomas S. Kilduff SRI International

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