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Constance L. Cepko

Constance L. Cepko

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
119
Citations
51940
World Ranking
589
National Ranking
354

Neuroscience

D-Index
118
Citations
52989
World Ranking
407
National Ranking
241

Genetics

D-Index
119
Citations
52559
World Ranking
391
National Ranking
200

Molecular Biology

D-Index
119
Citations
52559
World Ranking
270
National Ranking
160

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2002 - Member of the National Academy of Sciences
  • 1998 - Fellow of the American Academy of Arts and Sciences

Overview

Constance L. Cepko is affiliated with Harvard University in the United States and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research focuses primarily on molecular biology, cellular and molecular neuroscience, and ophthalmology, with additional work in immunology and biomedical engineering.

The scientist's recent papers demonstrate a wide range of topics and publication venues. Notable publications include:

  • SARS-CoV-2 detection using isothermal amplification and a rapid, inexpensive protocol for sample inactivation and purification (2020) in Proceedings of the National Academy of Sciences
  • Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors (2020) in Neuron
  • Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses (2021) in Science Translational Medicine
  • Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa (2021) in JCI Insight
  • Light-Seq: light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing (2022) in Nature Methods

The scientist collaborates frequently with several co-authors including Yunlu Xue, Sean K. Wang, Emma R. West, Brian Rabe, and Ryoji Amamoto.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • eLife
  • Development
  • JCI Insight

The main fields of study covered are biochemistry, genetics, and molecular biology, with major subfields in:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Ophthalmology
  • Immunology
  • Biomedical Engineering

The scientist's research topics span:

  • Retinal Development and Disorders
  • Photoreceptor and optogenetics research
  • Retinal Diseases and Treatments
  • Advanced biosensing and bioanalysis techniques
  • CRISPR and Genetic Engineering
  • Biosensors and Analytical Detection
  • SARS-CoV-2 detection and testing

Among the awards received are membership in the National Academy of Sciences since 2002 and fellowship of the American Academy of Arts and Sciences since 1998.

Best Publications

  • A common progenitor for neurons and glia persists in rat retina late in development

    David L. Turner;Constance L. Cepko

  • Electroporation and RNA interference in the rodent retina in vivo and in vitro.

    Takahiko Matsuda;Constance L. Cepko

  • Construction and applications of a highly transmissible murine retrovirus shuttle vector.

    Constance L. Cepko;Bryan E. Roberts;Richard C. Mulligan

  • Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.

    Takahisa Furukawa;Eric M Morrow;Constance L Cepko

  • Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

    Jack Price;David Turner;Constance Cepko

  • Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics.

    Karthik Shekhar;Sylvain W. Lapan;Sylvain W. Lapan;Irene E. Whitney;Nicholas M. Tran

  • Cell fate determination in the vertebrate retina

    Constance L. Cepko;Christopher P. Austin;Xianjie Yang;Macrene Alexiades

  • Vertebrate neural cell-fate determination: Lessons from the retina

    F. J. Livesey;C. L. Cepko

  • Multipotent neural cell lines can engraft and participate in development of mouse cerebellum.

    Evan Y. Snyder;David L. Deitcher;Christopher Walsh;Susan Arnold-Aldea

  • Lineage-independent determination of cell type in the embryonic mouse retina

    David L. Turner;Evan Y. Snyder;Constance L. Cepko

  • Controlled expression of transgenes introduced by in vivo electroporation

    Takahiko Matsuda;Constance L. Cepko

  • The origin and evolution of cell types

    Detlev Arendt;Jacob M. Musser;Clare V. H. Baker;Aviv Bergman;Aviv Bergman

  • rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells.

    Takahisa Furukawa;Siddhartha Mukherjee;Zheng-Zheng Bao;Eric M. Morrow

  • Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor

    Carol L. Freund;Cheryl Y. Gregory-Evans;Takahisa Furukawa;Myrto Papaioannou

  • Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration.

    Pamela S Lagali;David Balya;Gautam B Awatramani;Gautam B Awatramani;Thomas A Münch

  • Genomic Analysis of Mouse Retinal Development

    Seth Blackshaw;Sanjiv Harpavat;Jeff Trimarchi;Li Cai

  • Widespread dispersion of neuronal clones across functional regions of the cerebral cortex.

    Christopher Walsh;Constance L. Cepko

  • Retinopathy and attenuated circadian entrainment in Crx-deficient mice.

    Takahisa Furukawa;Takahisa Furukawa;Eric M. Morrow;Tiansen Li;Fred C. Davis

  • Control of Müller glial cell proliferation and activation following retinal injury.

    Michael A. Dyer;Constance L. Cepko

  • Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch

    C.P. Austin;D.E. Feldman;J.A. Ida;C.L. Cepko

Frequent Co-Authors

Takahisa Furukawa
Takahisa Furukawa Osaka University
Eric M. Morrow
Eric M. Morrow Brown University
Seth Blackshaw
Seth Blackshaw Johns Hopkins University School of Medicine
Michael A. Dyer
Michael A. Dyer St. Jude Children's Research Hospital
Donna M. Fekete
Donna M. Fekete Purdue University West Lafayette
Christopher A. Walsh
Christopher A. Walsh Howard Hughes Medical Institute
Jeffrey A. Golden
Jeffrey A. Golden Brigham and Women's Hospital
Frederick J. Livesey
Frederick J. Livesey University College London
Aviv Regev
Aviv Regev Genentech

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