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D-Index & Metrics

Molecular Biology

D-Index
100
Citations
35097
World Ranking
531
National Ranking
292

Medicine

D-Index
102
Citations
36628
World Ranking
7693
National Ranking
4002

Overview

Donald J. Zack is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience, with notable focus on subfields including Molecular Biology, Ophthalmology, Cellular and Molecular Neuroscience, Neurology, and Radiology, Nuclear Medicine and Imaging.

The research topics covered by Donald J. Zack include Retinal Development and Disorders, Glaucoma and retinal disorders, Retinal Diseases and Treatments, Neurogenesis and neuroplasticity mechanisms, Neuroinflammation and Neurodegeneration Mechanisms, Nerve injury and regeneration, and Neuroscience and Neural Engineering.

Among recent significant publications are:

  • Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries, 2021, Nature Communications
  • Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development, 2020, Developmental Cell
  • Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish, 2023, Frontiers in Science
  • High-throughput and high-content bioassay enables tuning of polyester nanoparticles for cellular uptake, endosomal escape, and systemic in vivo delivery of mRNA, 2022, Science Advances
  • Gelling hypotonic polymer solution for extended topical drug delivery to the eye, 2020, Nature Biomedical Engineering

Frequent coauthors who have collaborated extensively with Donald J. Zack include Cynthia Berlinicke, Jessica N. Cooke Bailey, Xitiz Chamling, Robert N. Weinreb, and Douglas Gaasterland.

Publishing consistently across a variety of platforms, Donald J. Zack has been featured most frequently in bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Nature Communications, Investigative Ophthalmology & Visual Science, and Proceedings of the National Academy of Sciences.

Best Publications

  • A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

    Lars G. Fritsche;Wilmar Igl;Jessica N.Cooke Bailey;Felix Grassmann

  • Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.

    H A Quigley;R W Nickells;L A Kerrigan;M E Pease

  • Seven new loci associated with age-related macular degeneration

    Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan

  • Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes.

    Shiming Chen;Qing Liang Wang;Zuqin Nie;Hui Sun

  • Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats.

    Harry A. Quigley;Stuart J. Mckinnon;Donald J. Zack;Mary Ellen Pease

  • Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma.

    Mary Ellen Pease;Stuart J. McKinnon;Harry A. Quigley;Lisa A. Kerrigan-Baumrind

  • TUNEL-positive ganglion cells in human primary open-angle glaucoma.

    Lisa A. Kerrigan;Donald J. Zack;Harry A. Quigley;Scott D. Smith

  • Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration

    Wei Chen;Dwight Stambolian;Albert O. Edwards;Kari E. Branham

  • Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

    Benjamin M. Neale;Jesen Fagerness;Jesen Fagerness;Robyn Reynolds;Lucia Sobrin

  • A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy

    Kang Zhang;Kang Zhang;Marina Kniazeva;Min Han;Wen Li

  • A locus control region adjacent to the human red and green visual pigment genes

    Yanshu Wang;Jennifer P. Macke;Shannath L. Merbs;Donald J. Zack

  • Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization.

    Naoyuki Okamoto;Takao Tobe;Sean F. Hackett;Hiroaki Ozaki

  • Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth.

    Elia J. Duh;Hoseong S. Yang;Izumi Suzuma;Masaru Miyagi

  • Gene therapy with brain-derived neurotrophic factor as a protection: Retinal ganglion cells in a rat glaucoma model

    Keith R. G. Martin;Harry A. Quigley;Donald J. Zack;Hana Levkovitch-Verbin

  • Pigment Epithelium-Derived Factor Inhibits Retinal and Choroidal Neovascularization

    Keisuke Mori;Elia Duh;Peter Gehlbach;Akira Ando

  • TiGER: a database for tissue-specific gene expression and regulation.

    Xiong Liu;Xueping Yu;Donald J Zack;Heng Zhu

  • Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression.

    Hiroaki Ozaki;Aimee Y. Yu;Neil Della;Keiko Ozaki

  • Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.

    Stuart J. McKinnon;Donna M. Lehman;Lisa A. Kerrigan-Baumrind;Carol A. Merges

  • A rare penetrant mutation in CFH confers high risk of age-related macular degeneration

    Soumya Raychaudhuri;Oleg Iartchouk;Kimberly Chin;Perciliz L Tan

  • Transgenic Mice with Increased Expression of Vascular Endothelial Growth Factor in the Retina: A New Model of Intraretinal and Subretinal Neovascularization.

    N Okamoto;T Tobe;S F Hackett;H Ozaki

Frequent Co-Authors

Peter A. Campochiaro
Peter A. Campochiaro Johns Hopkins University School of Medicine
Jiang Qian
Jiang Qian Johns Hopkins University School of Medicine
Harry A. Quigley
Harry A. Quigley Johns Hopkins University
Anand Swaroop
Anand Swaroop National Institutes of Health
Kang Zhang
Kang Zhang Macau University of Science and Technology
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Yutao Liu
Yutao Liu Augusta University
Janey L. Wiggs
Janey L. Wiggs Massachusetts Eye and Ear Infirmary
Michael A. Hauser
Michael A. Hauser Duke University
Louis R. Pasquale
Louis R. Pasquale Icahn School of Medicine at Mount Sinai

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