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Biology and Biochemistry

D-Index
99
Citations
29369
World Ranking
1614
National Ranking
900

Research.com Recognitions

  • 1987 - Fellow of Alfred P. Sloan Foundation

Overview

Thomas A. Reh is affiliated with the University of Washington in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology as well as Neuroscience, with extensive contributions spanning 89 and 34 publications respectively.

The scientist's subfields of study include Molecular Biology, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology, and Ophthalmology. Their main research topics cover areas such as Retinal Development and Disorders, Neurogenesis and neuroplasticity mechanisms, Single-cell and spatial transcriptomics, CRISPR and Genetic Engineering, Neuroinflammation and Neurodegeneration Mechanisms, RNA regulation and disease, and Advanced Fluorescence Microscopy Techniques.

Frequent publication venues for their work include bioRxiv (Cold Spring Harbor Laboratory), where they have 13 publications, followed by Cell Reports with 6 contributions. Other journals featuring their work are Glia (3 publications), SSRN Electronic Journal (3 publications), and Stem Cell Reports (2 publications).

Thomas A. Reh has collaborated regularly with several researchers, notably Levi Todd with 16 joint publications, Kiara C. Eldred with 14, Ian Glass with 11, Juliette Wohlschlegel with 10, and Marcus Hooper with 9.

Some of their recent papers include:

  • Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures, 2020, Cell Reports
  • Efficient stimulation of retinal regeneration from Müller glia in adult mice using combinations of proneural bHLH transcription factors, 2021, Cell Reports
  • STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina, 2020, Cell Reports
  • Microglia Suppress Ascl1-Induced Retinal Regeneration in Mice, 2020, Cell Reports
  • Reprogramming Müller glia to regenerate ganglion-like cells in adult mouse retina with developmental transcription factors, 2022, Science Advances

Thomas A. Reh was awarded the title of Fellow of the Alfred P. Sloan Foundation in 1987.

Best Publications

  • A comparative encyclopedia of DNA elements in the mouse genome

    Feng Yue;Feng Yue;Yong Cheng;Alessandra Breschi;Jeff Vierstra

  • Efficient generation of retinal progenitor cells from human embryonic stem cells

    Deepak A. Lamba;Mike O. Karl;Carol B. Ware;Thomas A. Reh

  • Müller glia are a potential source of neural regeneration in the postnatal chicken retina.

    Andy J. Fischer;Thomas A. Reh

  • Transplantation of human embryonic stem cell-derived photoreceptors restores some visual function in Crx-deficient mice.

    Deepak A. Lamba;Juliane Gust;Thomas A. Reh

  • A thyroid hormone receptor that is required for the development of green cone photoreceptors.

    Lily Ng;James B. Hurley;Blair Dierks;Maya Srinivas

  • Stimulation of functional neuronal regeneration from Müller glia in adult mice

    Nikolas L. Jorstad;Matthew S. Wilken;William N. Grimes;Stefanie G. Wohl

  • Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells.

    Deepak A. Lamba;Andrew McUsic;Roli K. Hirata;Pei Rong Wang

  • Development of the Nervous System

    Dan H. Sanes;Thomas A. Reh;William A. Harris

  • Stimulation of neural regeneration in the mouse retina

    Mike O. Karl;Susan Hayes;Branden R. Nelson;Kristine Tan

  • Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens.

    Andy J. Fischer;Thomas A. Reh

  • EGF and TGF-α stimulate retinal neuroepithelial cell proliferation in vitro

    Raymond M. Anchan;Thomas A. Reh;John Angello;Arthur Balliet

  • Making the gradient: thyroid hormone regulates cone opsin expression in the developing mouse retina.

    Melanie R. Roberts;Maya Srinivas;Douglas Forrest;Gabriella Morreale de Escobar

  • Retinoic acid promotes differentiation of photoreceptors in vitro

    M.W. Kelley;J.K. Turner;T.A. Reh

  • Extraocular mesenchyme patterns the optic vesicle during early eye development in the embryonic chick.

    Sabine Fuhrmann;Edward M. Levine;Thomas A. Reh

  • MIO‐M1 Cells and Similar Müller Glial Cell Lines Derived from Adult Human Retina Exhibit Neural Stem Cell Characteristics

    Jean M. Lawrence;Shweta Singhal;Bhairavi Bhatia;David J. Keegan

  • Potential of Müller glia to become neurogenic retinal progenitor cells.

    Andy J. Fischer;Thomas A. Reh

  • Transgenic expression of the proneural transcription factor Ascl1 in Müller glia stimulates retinal regeneration in young mice.

    Yumi Ueki;Matthew S. Wilken;Kristen E. Cox;Laura Chipman

  • Multipotential stem cells and progenitors in the vertebrate retina

    T. A. Reh;E. M. Levine

  • Eye-specific segregation requires neural activity in three-eyed Rana pipiens

    TA Reh;M Constantine-Paton

  • Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution

    Jeff Vierstra;Eric Rynes;Richard Sandstrom;Miaohua Zhang

Frequent Co-Authors

Andy J. Fischer
Andy J. Fischer The Ohio State University
Dan H. Sanes
Dan H. Sanes New York University
William A. Harris
William A. Harris University of Cambridge
Rachel O.L. Wong
Rachel O.L. Wong University of Washington
Mark Groudine
Mark Groudine Fred Hutchinson Cancer Research Center
John A. Stamatoyannopoulos
John A. Stamatoyannopoulos University of Washington
Richard Sandstrom
Richard Sandstrom University of Washington
Sheng Ding
Sheng Ding Tsinghua University

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