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Thomas D. Schmittgen

Thomas D. Schmittgen

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
256587
World Ranking
15317
National Ranking
6386

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Thomas D. Schmittgen is affiliated with the University of Florida in the United States. Their work spans across biochemistry, genetics, and molecular biology, with a significant focus on medicine. Key subfields of study include molecular biology, oncology, cancer research, surgery, and cellular and molecular neuroscience.

The primary topics addressed in their research involve pancreatic and hepatic oncology, microRNA in disease regulation, pancreatic function and diabetes, extracellular vesicles in disease, pancreatitis pathology and treatment, RNA modifications and cancer, and cancer-related molecular mechanisms.

Frequent publication venues where their research appears include Cancer Research, Cancer Epidemiology Biomarkers & Prevention, Neuroscience Letters, bioRxiv (Cold Spring Harbor Laboratory), and Gastroenterology.

Some recent papers authored or co-authored by Thomas D. Schmittgen are:

  • Alterations in mouse spinal cord and sciatic nerve microRNAs after the chronic constriction injury (CCI) model of neuropathic pain, 2020, Neuroscience Letters
  • Role of non-coding RNAs in tumor progression and metastasis in pancreatic cancer, 2021, Cancer and Metastasis Reviews
  • Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer, 2020, mSystems
  • Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia, 2022, Cell Death Discovery
  • Method for improved integrity of RNA isolated from Matrigel cultures, 2020, MethodsX

Frequent co-authors collaborating with Thomas D. Schmittgen include Jinmai Jiang, Corey M. Perkins, Martha Campbell-Thompson, Jamel Ali, and Julie K. Bray.

Thomas D. Schmittgen was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • ANALYSIS OF RELATIVE GENE EXPRESSION DATA USING REAL-TIME QUANTITATIVE PCR AND THE 2(-DELTA DELTA C(T)) METHOD

    Kenneth J. Livak;Thomas D. Schmittgen

  • Analyzing real-time PCR data by the comparative C(T) method.

    Thomas D Schmittgen;Kenneth J Livak

  • Detection of microRNA Expression in Human Peripheral Blood Microvesicles

    Melissa Piper Hunter;Noura Ismail;Noura Ismail;Xiaoli Zhang;Baltazar D. Aguda

  • Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR

    Thomas D Schmittgen;Brian A Zakrajsek

  • Quantitative Reverse Transcription–Polymerase Chain Reaction to Study mRNA Decay: Comparison of Endpoint and Real-Time Methods☆

    Thomas D. Schmittgen;Brian A. Zakrajsek;Alan G. Mills;Vladimir Gorn

  • Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines

    Fanyin Meng;Roger Henson;Molly Lang;Hania Wehbe

  • Expression profiling identifies microRNA signature in pancreatic cancer

    Eun Joo Lee;Yuriy Gusev;Jinmai Jiang;Gerard J. Nuovo

  • Ultraconserved Regions Encoding ncRNAs Are Altered in Human Leukemias and Carcinomas

    George A. Calin;Chang gong Liu;Manuela Ferracin;Terry Hyslop

  • Real-time PCR quantification of precursor and mature microRNA

    Thomas D. Schmittgen;Eun Joo Lee;Jinmai Jiang;Anasuya Sarkar

  • Association of MicroRNA Expression in Hepatocellular Carcinomas with Hepatitis Infection, Cirrhosis, and Patient Survival

    Jinmai Jiang;Yuriy Gusev;Yuriy Gusev;Ileana Aderca;Teresa A. Mettler

  • microRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

    Yunqing Li;Fadila Guessous;Ying Zhang;Charles DiPierro

  • Real-time expression profiling of microRNA precursors in human cancer cell lines

    Jinmai Jiang;Eun Joo Lee;Yuriy Gusev;Thomas D. Schmittgen

  • A high-throughput method to monitor the expression of microRNA precursors

    Thomas D. Schmittgen;Jinmai Jiang;Qian Liu;Liuqing Yang

  • Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.

    Jharna Datta;Huban Kutay;Mohd W. Nasser;Gerard J. Nuovo

  • Real-time quantitative PCR.

    Thomas D. Schmittgen

  • Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors.

    Eun Joo Lee;Myungwon Baek;Yuriy Gusev;Daniel J. Brackett

  • Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells

    Xiaohua Zhu;Mohamed Badawi;Steven Pomeroy;Dhruvitkumar S. Sutaria

  • MicroRNAs modulate the chemosensitivity of tumor cells

    Paul E. Blower;Ji Hyun Chung;Joseph S. Verducci;Shili Lin

  • Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice.

    Bo Wang;Sarmila Majumder;Gerard Nuovo;Huban Kutay

  • Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma

    Jong-Kook Park;Eun Joo Lee;Christine Esau;Thomas D. Schmittgen

Frequent Co-Authors

Gerard J. Nuovo
Gerard J. Nuovo The Ohio State University
Carlo M. Croce
Carlo M. Croce The Ohio State University
George A. Calin
George A. Calin The University of Texas MD Anderson Cancer Center
Stefano Volinia
Stefano Volinia University of Ferrara
Clay B. Marsh
Clay B. Marsh West Virginia University
Lewis R. Roberts
Lewis R. Roberts Mayo Clinic
Massimo Negrini
Massimo Negrini University of Ferrara
Samson T. Jacob
Samson T. Jacob The Ohio State University
Tushar Patel
Tushar Patel American Gastroenterological Association

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