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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10611
World Ranking
13941
National Ranking
5890

Overview

Budd A. Tucker is affiliated with the University of Iowa in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broader fields, their work focuses on subfields including Molecular Biology, Ophthalmology, Radiology, Nuclear Medicine and Imaging, Cellular and Molecular Neuroscience, and Biomedical Engineering.

The scientist's research topics cover a range of areas related to retinal health and vision science. These include:

  • Retinal Development and Disorders
  • Retinal Diseases and Treatments
  • Single-cell and spatial transcriptomics
  • CRISPR and Genetic Engineering
  • Neuroscience and Neural Engineering
  • Pluripotent Stem Cells Research
  • Retinal Imaging and Analysis

This expert has published extensively in several journals and platforms, with a frequent presence in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Experimental Eye Research
  • Human Molecular Genetics
  • Progress in Retinal and Eye Research
  • Stem Cells Translational Medicine

Among the recent papers authored or coauthored are:

  • "Spectacle: An interactive resource for ocular single-cell RNA sequencing data analysis," 2020, Experimental Eye Research
  • "Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype," 2020, Microvascular Research
  • "Single-cell RNA sequencing in vision research: Insights into human retinal health and disease," 2020, Progress in Retinal and Eye Research
  • "Choroidal endothelial and macrophage gene expression in atrophic and neovascular macular degeneration," 2022, Human Molecular Genetics
  • "Retinal Tropism and Transduction of Adeno-Associated Virus Varies by Serotype and Route of Delivery (Intravitreal, Subretinal, or Suprachoroidal) in Rats," 2020, Human Gene Therapy

The scientist has collaborated frequently with several researchers. Most frequent coauthors include:

  • Robert F. Mullins
  • Edwin M. Stone
  • Andrew P. Voigt
  • Ian C. Han
  • Nathaniel K. Mullin

Best Publications

  • Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors.

    Magali Saint-Geniez;Arindel S. R. Maharaj;Tony E. Walshe;Budd A. Tucker

  • Clinically Focused Molecular Investigation of 1000 Consecutive Families with Inherited Retinal Disease.

    Edwin M. Stone;Edwin M. Stone;Jeaneen L. Andorf;Jeaneen L. Andorf;S. Scott Whitmore;S. Scott Whitmore;Adam P. DeLuca;Adam P. DeLuca

  • Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

    Budd A. Tucker;In-Hyun Park;Sara D. Qi;Henry J. Klassen

  • Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration.

    Andrew P. Voigt;Kelly Mulfaul;Kelly Mulfaul;Nathaniel K. Mullin;Nathaniel K. Mullin;Miles J. Flamme-Wiese;Miles J. Flamme-Wiese

  • ABCB5 is a limbal stem cell gene required for corneal development and repair

    Bruce R. Ksander;Paraskevi E. Kolovou;Brian J. Wilson;Karim R. Saab

  • Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa

    Budd A. Tucker;Todd E. Scheetz;Robert F. Mullins;Adam P. DeLuca

  • Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa

    Budd A Tucker;Robert F Mullins;Luan M Streb;Kristin Anfinson

  • Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.

    S. Scott Whitmore;Elliott H. Sohn;Kathleen R. Chirco;Arlene V. Drack

  • Endurance exercise regimens induce differential effects on brain-derived neurotrophic factor, synapsin-I and insulin-like growth factor I after focal ischemia.

    M. Ploughman;S. Granter-Button;G. Chernenko;B.A. Tucker

  • The synergistic effects of NGF and IGF‐1 on neurite growth in adult sensory neurons: convergence on the PI 3‐kinase signaling pathway

    David M. Jones;Budd A. Tucker;Masuma Rahimtula;Karen M. Mearow

  • The membrane attack complex in aging human choriocapillaris: relationship to macular degeneration and choroidal thinning.

    Robert F. Mullins;Desi P. Schoo;Elliott H. Sohn;Miles J. Flamme-Wiese

  • Non-exomic and synonymous variants in ABCA4 are an important cause of Stargardt disease

    Terry A. Braun;Robert F. Mullins;Alex H. Wagner;Jeaneen L. Andorf

  • Structural and molecular changes in the aging choroid: implications for age-related macular degeneration

    K R Chirco;E H Sohn;E M Stone;B A Tucker

  • Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration

    Erin R. Burnight;Manav Gupta;Luke A. Wiley;Kristin R. Anfinson

  • Basal exon skipping and genetic pleiotropy: A predictive model of disease pathogenesis

    Theodore G. Drivas;Adam P. Wojno;Budd A. Tucker;Edwin M. Stone

  • CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype.

    E R Burnight;L A Wiley;A V Drack;T A Braun

  • Molecular characterization of foveal versus peripheral human retina by single-cell RNA sequencing.

    A.P. Voigt;S.S. Whitmore;M.J. Flamme-Wiese;M.J. Riker

  • Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases.

    Luke A. Wiley;Erin R. Burnight;Allison E. Songstad;Arlene V. Drack

  • CNS Progenitor Cells Promote a Permissive Environment for Neurite Outgrowth via a Matrix Metalloproteinase-2-Dependent Mechanism

    Yiqin Zhang;Henry J Klassen;Budd A Tucker;Maria-Thereza R Perez

  • Transcriptomic analysis across nasal, temporal, and macular regions of human neural retina and RPE/choroid by RNA-Seq.

    S. Scott Whitmore;S. Scott Whitmore;Alex H. Wagner;Adam P. DeLuca;Adam P. DeLuca;Arlene V. Drack;Arlene V. Drack

Frequent Co-Authors

Edwin M. Stone
Edwin M. Stone University of Iowa
Robert F. Mullins
Robert F. Mullins University of Iowa
Todd E. Scheetz
Todd E. Scheetz University of Iowa
Michael J. Young
Michael J. Young Harvard University
Val C. Sheffield
Val C. Sheffield University of Iowa
John H. Fingert
John H. Fingert University of Iowa
George Q. Daley
George Q. Daley Boston Children's Hospital
Samuel G. Jacobson
Samuel G. Jacobson University of Pennsylvania
Patricia A. D'Amore
Patricia A. D'Amore Massachusetts Eye and Ear Infirmary
In-Hyun Park
In-Hyun Park Yale University

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