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Genetics

D-Index
56
Citations
14620
World Ranking
3472
National Ranking
1504

Overview

Todd E. Scheetz is affiliated with the University of Iowa in the United States. Their research primarily focuses on ophthalmology, molecular biology, and related biomedical fields with a particular emphasis on retinal diseases and disorders.

The main fields of study for this scientist include Medicine and Biochemistry, Genetics and Molecular Biology. Their work contributes notably to several subfields such as Ophthalmology, Molecular Biology, Radiology, Nuclear Medicine and Imaging, Neurology, and Immunology.

Key topics frequently addressed in their research are:

  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Retinal Development and Disorders
  • Retinal Imaging and Analysis
  • Single-cell and spatial transcriptomics
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Retinopathy of Prematurity Studies

Their recent publications include studies focused on single-cell RNA sequencing and retinal health, demonstrating a blend of molecular biology techniques and clinical relevance in ophthalmic research. Some notable papers are:

  • "Spectacle: An interactive resource for ocular single-cell RNA sequencing data analysis" (2020), Experimental Eye Research
  • "Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype" (2020), Microvascular Research
  • "Single-cell RNA sequencing in vision research: Insights into human retinal health and disease" (2020), Progress in Retinal and Eye Research
  • "Choroidal endothelial and macrophage gene expression in atrophic and neovascular macular degeneration" (2022), Human Molecular Genetics
  • "Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations" (2020), Cells

Frequent coauthors in their collaborative work include Edwin M. Stone, Robert F. Mullins, John H. Fingert, Budd A. Tucker, and Andrew P. Voigt. These partnerships have contributed to building a comprehensive understanding of retinal diseases at the molecular and cellular levels.

The scientist has published multiple papers across renowned venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Molecular Genetics
  • JAMA Ophthalmology
  • Scientific Reports
  • Investigative Ophthalmology & Visual Science

Best Publications

  • Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

    Robert L Strausberg;Elise A Feingold;Lynette H Grouse;Jeffery G Derge

  • The status, quality, and expansion of the NIH full-length cDNA project: The Mammalian Gene Collection (MGC)

    Daniela S. Gerhard;Lukas Wagner;Elise A. Feingold;Carolyn M. Shenmen

  • Homozygosity Mapping With SNP Arrays Identifies TRIM32, an E3 Ubiquitin Ligase, as a Bardet-Biedl Syndrome Gene (BBS11)

    Annie P. Chiang;John S. Beck;Hsan Jan Yen;Marwan K. Tayeh

  • Clonal selection drives genetic divergence of metastatic medulloblastoma

    Xiaochong Wu;Paul A. Northcott;Adrian Dubuc;Adam J. Dupuy

  • An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

    Catherine A. Brownstein;Alan H. Beggs;Nils Homer;Barry Merriman

  • The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

    Alejandro Antonio Pezzulo;Timothy D. Starner;Todd E. Scheetz;Geri L. Traver

  • Clinically Focused Molecular Investigation of 1000 Consecutive Families with Inherited Retinal Disease.

    Edwin M. Stone;Edwin M. Stone;Jeaneen L. Andorf;Jeaneen L. Andorf;S. Scott Whitmore;S. Scott Whitmore;Adam P. DeLuca;Adam P. DeLuca

  • Comprehensive genetic testing for hereditary hearing loss using massively parallel sequencing

    A. Eliot Shearer;Adam P. DeLuca;Michael S. Hildebrand;Kyle R. Taylor

  • A BBSome subunit links ciliogenesis, microtubule stability, and acetylation.

    Alexander V. Loktev;Qihong Zhang;John S. Beck;Charles C. Searby

  • Regulation of gene expression in the mammalian eye and its relevance to eye disease

    Todd E. Scheetz;Kwang Youn A Kim;Ruth E. Swiderski;Alisdair R. Philp

  • Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration.

    Andrew P. Voigt;Kelly Mulfaul;Kelly Mulfaul;Nathaniel K. Mullin;Nathaniel K. Mullin;Miles J. Flamme-Wiese;Miles J. Flamme-Wiese

  • Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa

    Budd A. Tucker;Todd E. Scheetz;Robert F. Mullins;Adam P. DeLuca

  • Copy number variations on chromosome 12q14 in patients with normal tension glaucoma

    John H. Fingert;Alan L. Robin;Jennifer L. Stone;Ben R. Roos

  • Migration of the plastid genome to the nucleus in a peridinin dinoflagellate.

    Jeremiah D. Hackett;Hwan Su Yoon;M. Bento Soares;Maria F. Bonaldo

  • Insights into a dinoflagellate genome through expressed sequence tag analysis

    Jeremiah D Hackett;Todd E Scheetz;Hwan Su Yoon;Marcelo B Soares

  • Anopheles gambiae pilot gene discovery project: identification of mosquito innate immunity genes from expressed sequence tags generated from immune-competent cell lines.

    George Dimopoulos;Thomas L. Casavant;Shereen Chang;Todd Scheetz

  • Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis

    Andrew M. Wier;Andrew M. Wier;Spencer V. Nyholm;Mark J. Mandel;Mark J. Mandel;R. Prisca Massengo-Tiassé

  • A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice.

    Adam J. Dupuy;Laura M. Rogers;Jinsil Kim;Kishore Nannapaneni

  • Identifying Components of the NF-κB Pathway in the Beneficial Euprymna scolopes-Vibrio fischeri Light Organ Symbiosis

    Michael S. Goodson;Mila Kojadinovic;Joshua V. Troll;Todd E. Scheetz

  • Utilizing Ethnic-Specific Differences in Minor Allele Frequency to Recategorize Reported Pathogenic Deafness Variants

    A. Eliot Shearer;Robert W. Eppsteiner;Kevin T. Booth;Sean S. Ephraim

Frequent Co-Authors

Edwin M. Stone
Edwin M. Stone University of Iowa
Val C. Sheffield
Val C. Sheffield University of Iowa
John H. Fingert
John H. Fingert University of Iowa
Robert F. Mullins
Robert F. Mullins University of Iowa
Michael D. Abràmoff
Michael D. Abràmoff University of Iowa
Budd A. Tucker
Budd A. Tucker University of Iowa
Richard J.H. Smith
Richard J.H. Smith University of Iowa
Paul B. McCray
Paul B. McCray University of Iowa
Marcelo B. Soares
Marcelo B. Soares University of Illinois at Peoria
Abbot F. Clark
Abbot F. Clark University of North Texas Health Science Center

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