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Martha Constantine-Paton

Martha Constantine-Paton

D-Index & Metrics

Neuroscience

D-Index
58
Citations
17426
World Ranking
4104
National Ranking
1864

Research.com Recognitions

  • 2013 - Fellow of the American Academy of Arts and Sciences
  • 1982 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Martha Constantine-Paton is affiliated with the Massachusetts Institute of Technology (MIT) in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, as well as Neuroscience. Within these areas, their work spans molecular biology, cellular and molecular neuroscience, cell biology, genetics, and plant science.

Their main research topics include cellular transport and secretion, CRISPR and genetic engineering, genetics and neurodevelopmental disorders, genetic neurodegenerative diseases, chromosomal and genetic variations, amyotrophic lateral sclerosis (ALS) research, and mitochondrial function and pathology.

The scientist has a notable publication record with several recent papers:

  • "Myosin Va Brain-Specific Mutation Alters Mouse Behavior and Disrupts Hippocampal Synapses", 2020, published in eNeuro
  • "Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer", 2023, published in BMC Biology
  • "Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death", 2024, published in Molecular Medicine
  • "Removal of a genomic duplication by double-nicking CRISPR restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer", 2023, published in bioRxiv (Cold Spring Harbor Laboratory)
  • "Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death", 2024, published in bioRxiv (Cold Spring Harbor Laboratory)

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • BMC Biology
  • eNeuro
  • Molecular Medicine
  • UNC Libraries

Collaboration is a significant aspect of their academic activity. Frequent co-authors include Fernando J. Bustos, Swarna Pandian, Jianping Zhao, Henny Haensgen, and Yasunobu Murata.

The scientist has been recognized with awards such as the Fellow of the American Academy of Arts and Sciences in 2013 and the Fellow of the John Simon Guggenheim Memorial Foundation in 1982.

Best Publications

  • Independent optical excitation of distinct neural populations

    Nathan C Klapoetke;Yasunobu Murata;Sung Soo Kim;Stefan R Pulver

  • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

    Marius Wernig;Jian Ping Zhao;Jan Pruszak;Eva Hedlund

  • Microarray analysis of microRNA expression in the developing mammalian brain

    Eric A Miska;Ezequiel Alvarez-Saavedra;Matthew Townsend;Matthew Townsend;Akira Yoshii

  • Patterned activity, synaptic convergence, and the NMDA receptor in developing visual pathways

    M Constantine-Paton;H T Cline;E Debski

  • Postsynaptic BDNF-TrkB Signaling in Synapse Maturation, Plasticity, and Disease

    Akira Yoshii;Martha Constantine-Paton

  • N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes.

    Hollis T. Cline;Elizabeth A. Debski;Martha Constantine-Paton

  • BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation

    Akira Yoshii;Martha Constantine-Paton;Martha Constantine-Paton

  • NMDA receptor-mediated control of protein synthesis at developing synapses.

    A. J. Scheetz;Angus C. Nairn;Martha Constantine-Paton;Martha Constantine-Paton

  • N-methyl-D-aspartate receptor antagonists disrupt the formation of a mammalian neural map.

    David K. Simon;Glen T. Prusky;Dennis D. M. O'Leary;Martha Constantine-Paton

  • NMDA receptor antagonists disrupt the retinotectal topographic map

    Hollis T. Cline;Martha Constantine-Paton

  • Modulation of NMDA receptor function: implications for vertebrate neural development.

    A. J. Scheetz;Martha Constantine-Paton

  • Eye-specific termination bands in tecta of three-eyed frogs.

    Martha Constantine-Paton;Margaret I. Law

  • Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal.

    Brigitte van Zundert;Brigitte van Zundert;Akira Yoshii;Martha Constantine-Paton

  • Eye-specific segregation requires neural activity in three-eyed Rana pipiens

    TA Reh;M Constantine-Paton

  • NMDA receptor agonist and antagonists alter retinal ganglion cell arbor structure in the developing frog retinotectal projection

    Hollis T. Cline;Martha Constantine-Paton

  • Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis

    Brigitte Van Zundert;Marieke H. Peuscher;Meri Hynynen;Adam Chen

  • LTP and activity-dependent synaptogenesis: the more alike they are, the more different they become

    Martha Constantine-Paton;Hollis T Cline

  • Distinct Roles of NR2A and NR2B Cytoplasmic Tails in Long-Term Potentiation

    Kelly A. Foster;Nathan McLaughlin;Dieter Edbauer;Marnie Phillips

  • A cell surface molecule distributed in a dorsoventral gradient in the perinatal rat retina

    Martha Constantine-Paton;Andrew S. Blum;Rosalia Mendez-Otero;Rosalia Mendez-Otero;Colin J. Barnstable

  • Retinal ganglion cell terminals change their projection sites during larval development of Rana pipiens

    TA Reh;M Constantine-Paton

Frequent Co-Authors

Hollis T. Cline
Hollis T. Cline Scripps Research Institute
Rosalia Mendez-Otero
Rosalia Mendez-Otero Federal University of Rio de Janeiro
Yong Zhang
Yong Zhang Chinese Academy of Sciences
Vivek Jayaraman
Vivek Jayaraman Howard Hughes Medical Institute
Gane Ka-Shu Wong
Gane Ka-Shu Wong University of Alberta
Glen T. Prusky
Glen T. Prusky Cornell University
Colin J. Barnstable
Colin J. Barnstable Penn State Milton S. Hershey Medical Center
Morgan Sheng
Morgan Sheng Broad Institute

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