World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
74
Citations
19577
World Ranking
2113
National Ranking
1006

Biology and Biochemistry

D-Index
75
Citations
25570
World Ranking
5239
National Ranking
2492

Research.com Recognitions

  • 1984 - Fellow of Alfred P. Sloan Foundation

Overview

Colin J. Barnstable is affiliated with the Penn State Milton S. Hershey Medical Center in the United States. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with specific work in several subfields including molecular biology, ophthalmology, physiology, radiology, nuclear medicine and imaging, and public health, environmental and occupational health.

Their research topics cover a range of specialized subjects related to eye health and cellular function. These include:

  • Retinal diseases and treatments
  • Glaucoma and retinal disorders
  • Retinal development and disorders
  • Adipose tissue and metabolism
  • Mitochondrial function and pathology
  • Ocular surface and contact lens
  • Corneal surgery and treatments

Barnstable has published extensively in various scientific journals. Frequent publication venues include:

  • Experimental Eye Research
  • International Journal of Molecular Sciences
  • Asia-Pacific Journal of Ophthalmology
  • Progress in Retinal and Eye Research
  • The Ocular Surface

Recent papers by Barnstable include:

  • "Uncoupling proteins in the mitochondrial defense against oxidative stress," 2021, Progress in Retinal and Eye Research
  • "PEDF is an endogenous inhibitor of VEGF-R2 angiogenesis signaling in endothelial cells," 2021, Experimental Eye Research
  • "Inhibition of Epigenetic Modifiers LSD1 and HDAC1 Blocks Rod Photoreceptor Death in Mouse Models of Retinitis Pigmentosa," 2021, Journal of Neuroscience
  • "A PEDF peptide mimetic effectively relieves dry eye in a diabetic murine model by restoring corneal nerve, barrier, and lacrimal gland function," 2023, The Ocular Surface
  • "Novel Regulators of Retina Neovascularization: A Proteomics Approach," 2021, Journal of Proteome Research

Collaborative efforts have been a notable aspect of Barnstable's work, with frequent coauthors including:

  • Joyce Tombran-Tink
  • Xiaomin Zhang
  • Xiaorong Li
  • Mingliang Zhang
  • Evgenya Y. Popova

An award received by Barnstable is the Fellowship of the Alfred P. Sloan Foundation awarded in 1984.

Best Publications

  • Complement Factor H Polymorphism in Age-Related Macular Degeneration

    Robert J. Klein;Caroline J. Zeiss;Emily Y. Chew;Jen-yue Tsai

  • Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis.

    C.J. Barnstable;W.F. Bodmer;G. Brown;G. Galfre

  • HTRA1 promoter polymorphism in wet age-related macular degeneration

    A. DeWan;M. Liu;S. Hartman;S.S.M. Zhang

  • Monoclonal antibodies for analysis of the HLA system.

    Frances M. Brodsky;Peter Parham;Colin J. Barnstable;M. J. Crumpton

  • Use of a Monoclonal Antibody (W6/32) in Structural Studies of HLA-A,B,C Antigens

    Peter Parham;Colin J. Barnstable;Walter F. Bodmer

  • PEDF: a multifaceted neurotrophic factor.

    Joyce Tombran-Tink;Colin J. Barnstable

  • A marker of early amacrine cell development in rat retina

    Colin J. Barnstable;Raphael Hofstein;Kimio Akagawa

  • Monoclonal antibodies which recognize different cell types in the rat retina.

    Colin J. Barnstable

  • Thy-1 antigen: A ganglion cell specific marker in rodent retina

    C.J. Barnstable;U.C. Dräger

  • Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential.

    Colin J Barnstable;Joyce Tombran-Tink

  • Retinal ganglion cells express a cGMP-gated cation conductance activatable by nitric oxide donors

    Iqbal Ahmad;Trese Leinders-Zufall;Jeffery D. Kocsis;Gordon M. Shepherd

  • The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin.

    Bento Arce‐Gomez;Elizabeth A. Jones;Colin J. Barnstable;Ellen Solomon

  • Coexpression of opsin- and VIP-like-immunoreactivity in CSF-contacting neurons of the avian brain

    Rae Silver;P. Witkovsky;P. Horvath;V. Alones

  • Antibodies against filamentous components in discrete cell types of the mouse retina

    UC Drager;DL Edwards;CJ Barnstable

  • Molecular structure of human histocompatibility antigens: the HLA‐C series

    D. Snary;C.J. Barnstable;W.F. Bodmer;M.J. Crumpton

  • Uncoupling protein 2 prevents neuronal death including that occurring during seizures: a mechanism for preconditioning.

    Sabrina Diano;Russell T. Matthews;Peter Patrylo;Lichuan Yang

  • Osteoblasts and osteoclasts express PEDF, VEGF-A isoforms, and VEGF receptors: possible mediators of angiogenesis and matrix remodeling in the bone

    J Tombran-Tink;C.J Barnstable

  • Expression of HLA system antigens on placenta.

    P. N. Goodfellow;P. N. Goodfellow;P. N. Goodfellow;C. J. Barnstable;W. F. Bodmer;W. F. Bodmer;D. Snary;D. Snary

  • Neurotoxic effects of low doses of glutamate on purified rat retinal ganglion cells.

    Yasumasa Otori;Ji Ye Wei;Colin J. Barnstable

  • Monoclonal Antibody to Thy-1 Enhances Regeneration of Processes by Rat Retinal Ganglion Cells In Culture

    Dana Leifer;Stuart A. Lipton;Stuart A. Lipton;Colin J. Barnstable;Colin J. Barnstable;Richard H. Masland

  • Complement factor H polymorphism in age-related macular degeneration

    R.J. Klein;C. Zeiss;E.Y. Chew;J.Y. Tsai

Frequent Co-Authors

Joyce Tombran-Tink
Joyce Tombran-Tink Pennsylvania State University
Walter F. Bodmer
Walter F. Bodmer University of Oxford
Michael J. Crumpton
Michael J. Crumpton EMF Biological Research Trust
Tamas L. Horvath
Tamas L. Horvath Yale University
Janice R. Naegele
Janice R. Naegele Wesleyan University
Frank Zufall
Frank Zufall Saarland University
Rosalia Mendez-Otero
Rosalia Mendez-Otero Federal University of Rio de Janeiro
Stuart A. Lipton
Stuart A. Lipton Scripps Research Institute
Sabrina Diano
Sabrina Diano Columbia University

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