Joyce Tombran-Tink

Overview

Best Publications

• PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity.

  Joyce Tombran-Tink;Gerald G. Chader;Lincoln V. Johnson

  844
  Citations

• Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family.

  Fintan R. Steele;Gerald J. Chader;Lincoln V. Johnson;Joyce Tombran-Tink

  672
  Citations

• PEDF: a multifaceted neurotrophic factor.

  Joyce Tombran-Tink;Colin J. Barnstable

  487
  Citations

• Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells.

  J Tombran-Tink;L V Johnson

  382
  Citations

• Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF.

  Kyoko Ohno-Matsui;Ikuo Morita;Joyce Tombran-Tink;Joyce Tombran-Tink;David Mrazek;David Mrazek

  376
  Citations

• EXPRESSION, SECRETION, AND AGE-RELATED DOWNREGULATION OF PIGMENT EPITHELIUM-DERIVED FACTOR, A SERPIN WITH NEUROTROPHIC ACTIVITY

  Joyce Tombran-Tink;Sunil M. Shivaram;Gerald J. Chader;Lincoln V. Johnson

  316
  Citations

• Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential.

  Colin J Barnstable;Joyce Tombran-Tink

  304
  Citations

• In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor.

  Wei Cao;Joyce Tombran-Tink;Rajesh Elias;Steven Sezate

  284
  Citations

• Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin.

  J. Tombran-Tink;K. Mazuruk;I. R. Rodriguez;D. Chung

  282
  Citations

• Pigment epithelium-derived factor protects cultured retinal neurons against hydrogen peroxide-induced cell death.

  W. Cao;J. Tombran-Tink;W. Chen;D. Mrazek

  245
  Citations

• Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration.

  Masako M. Bilak;Andrea M. Corse;Stephan R. Bilak;Mohamed Lehar

  241
  Citations

• Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal

  Monica M. Jablonski;Joyce Tombran-Tink;David A. Mrazek;Alessandro Iannaccone

  236
  Citations

• Osteoblasts and osteoclasts express PEDF, VEGF-A isoforms, and VEGF receptors: possible mediators of angiogenesis and matrix remodeling in the bone

  J Tombran-Tink;C.J Barnstable

  231
  Citations

• Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants.

  Yuan He;Kar Wah Leung;Yue Hong Zhang;Shan Duan

  199
  Citations

• Expression of pigment epithelium-derived factor in normal adult rat eye and experimental choroidal neovascularization.

  Nahoko Ogata;Mitsumasa Wada;Tsuyoshi Otsuji;Nobuo Jo

  191
  Citations

• Vitreous and aqueous concentrations of proangiogenic, antiangiogenic factors and other cytokines in diabetic retinopathy patients with macular edema: Implications for structural differences in macular profiles.

  Jignesh I Patel;Joyce Tombran-Tink;Joyce Tombran-Tink;Phil G Hykin;Zdenek J Gregor

  188
  Citations

• Pigment epithelium-derived factor in the vitreous is low in diabetic retinopathy and high in rhegmatogenous retinal detachment.

  Nahoko Ogata;Joyce Tombran-Tink;Joyce Tombran-Tink;Maki Nishikawa;Tetsuya Nishimura

  186
  Citations

• Pigment epithelium-derived factor (PEDF) peptide eye drops reduce inflammation, cell death and vascular leakage in diabetic retinopathy in Ins2(Akita) mice.

  Yanling Liu;Lan Franco Leo;Corban McGregor;Anzor Grivitishvili

  156
  Citations

• Therapeutic prospects for PEDF: more than a promising angiogenesis inhibitor

  Joyce Tombran-Tink;Colin J. Barnstable

  151
  Citations

• Neuroprotection by pigment epithelial-derived factor against glutamate toxicity in developing primary hippocampal neurons

  Mark A. DeCoster;Esteban Schabelman;Joyce Tombran-Tink;Nicolas G. Bazan

  148
  Citations