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Neuroscience

D-Index
47
Citations
6446
World Ranking
6538
National Ranking
549

Overview

Paul G. Layer is affiliated with the Technical University of Darmstadt in Germany. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Pharmacology, Computational Theory and Mathematics, Cellular and Molecular Neuroscience, and Biomedical Engineering.

Their recent publications cover a range of topics including cholinesterase and neurodegenerative diseases, nicotinic acetylcholine receptors, retinal development and disorders, computational drug discovery methods, photoreceptor and optogenetics research, CRISPR and genetic engineering, and DNA repair mechanisms.

  • Non-neuronal Role of Acetylcholinesterase in Bone Development and Degeneration (2021) published in Frontiers in Cell and Developmental Biology
  • Cholinergic control of bone development and beyond (2020) published in International Immunopharmacology
  • Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans (2020) published in Cells
  • Post-genomics, Evo-Devo and the recurrence of teleologic thought† (2022) published in BioCosmos
  • In a century from agitated cells to human organoids (2024) published in Journal of Neuroscience Methods

Paul G. Layer has frequently collaborated with several co-authors, including:

  • Spieker Janine
  • Xiaohe Luo
  • Marianne Lauwers
  • Chunyi Wen
  • Johannes L. Frieß

The scientist's work has been published across several venues, notably:

  • Frontiers in Cell and Developmental Biology
  • International Immunopharmacology
  • Cells
  • BioCosmos
  • Journal of Neuroscience Methods

Best Publications

  • Novel functions of cholinesterases in development, physiology and disease

    Paul G. Layer;Elmar Willbold

  • Cholinesterases regulate neurite growth of chick nerve cells in vitro by means of a non-enzymatic mechanism

    Paul G. Layer;Thomas Weikert;Regina Alber

  • Of layers and spheres: the reaggregate approach in tissue engineering.

    Paul G Layer;Andrea Robitzki;Andrée Rothermel;Elmar Willbold

  • Cholinesterases during development of the avian nervous system.

    Paul Gottlob Layer

  • Comparative localization of acetylcholinesterase and pseudocholinesterase during morphogenesis of the chicken brain

    Paul G. Layer

  • Spatiotemporal relationship of embryonic cholinesterases with cell proliferation in chicken brain and eye

    Paul G. Layer;Olaf Sporns

  • Cholinesterases preceding major tracts in vertebrate neurogenesis.

    Paul G. Layer

  • Sequential activation of butyrylcholinesterase in rostral half somites and acetylcholinesterase in motoneurones and myotomes preceding growth of motor axons.

    P.G. Layer;R. Alber;F.G. Rathjen

  • Acetylcholinesterase in cell adhesion, neurite growth and network formation.

    Laura E. Paraoanu;Paul G. Layer

  • Neurotransmitters in embryogenesis: by G. A. Buznikov (translated from the Russian by A. Bastow), Soviet Scientific Supplement Series published by Harwood Academic Publishers, 1990. (Original Russian version published by Nauka, 1986) $150.00 (vii + 526 pages) ISBN 3 7186 4877 6

    Paul G. Layer

  • Nerve growth factor-induced differentiation of PC12 cells: evaluation of changes in RNA and DNA metabolism

    PW Gunning;GE Landreth;P Layer;M Ignatius

  • An in vitro model of proliferation and differentiation of the chick retina: coaggregates of retinal and pigment epithelial cells

    G. Vollmer;Paul G. Layer

  • Muller glia cells and their possible roles during retina differentiation in vivo and in vitro

    Elmar Willbold;P. G. Layer

  • Quantitative development and molecular forms of acetyl- and butyrylcholinesterase during morphogenesis and synaptogenesis of chick brain and retina.

    Paul G. Layer;Regina Alber;Olaf Sporns

  • Reaggregation of embryonic chick retina cells: Pigment epithelial cells induce a high order of stratification

    G. Vollmer;Paul G. Layer;A. Gierer

  • Embryonic chicken retinal cells can regenerate all cell layers in vitro, but ciliary pigmented cells induce their correct polarity.

    Paul G. Layer;Elmar Willbold

  • RPE specification in the chick is mediated by surface ectoderm-derived BMP and Wnt signalling

    Jörg Steinfeld;Ichie Steinfeld;Ichie Steinfeld;Nicola Coronato;Meggi-Lee Hampel

  • Interaction between organophosphate compounds and cholinergic functions during development.

    M. G. Aluigi;C. Angelini;C. Falugi;R. Fossa

  • Patterning of chick brain vesicles as revealed by peanut agglutinin and cholinesterases.

    Paul G. Layer;R. Alber

  • Developmental maps of acetylcholinesterase and G4-antigen of the early chicken brain: long-distance tracts originate from AChE-producing cell bodies.

    Thomas Weikert;Fritz G. Rathjen;Paul G. Layer

  • Non-classical actions of cholinesterases : Role in cellular differentiation, tumorigenesis and Alzheimer's disease

    Paul G. Layer

Frequent Co-Authors

Olaf Sporns
Olaf Sporns Indiana University
Robert K. McNamara
Robert K. McNamara University of Cincinnati Medical Center
Sonja A. Kotz
Sonja A. Kotz Maastricht University
Colin J. Barnstable
Colin J. Barnstable Penn State Milton S. Hershey Medical Center
Robert H. Lenox
Robert H. Lenox University of New England
Stephan Kröger
Stephan Kröger Ludwig-Maximilians-Universität München
Rüdiger Klein
Rüdiger Klein Max Planck Society
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society
Heinrich H. Bülthoff
Heinrich H. Bülthoff Max Planck Institute for Biological Cybernetics
Klaus Unsicker
Klaus Unsicker University of Freiburg

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