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Biology and Biochemistry

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100
Citations
34435
World Ranking
1526
National Ranking
858

Medicine

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101
Citations
35850
World Ranking
8016
National Ranking
4163

Overview

David R. Hinton is affiliated with the University of Southern California in the United States. Their research focuses primarily on the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. They have significant contributions in subfields such as Molecular Biology, Ophthalmology, Cellular and Molecular Neuroscience, Radiology, Nuclear Medicine and Imaging, and Immunology.

Their work extensively covers topics related to retinal health and neurological conditions. Main areas of study include:

  • Retinal Development and Disorders
  • Retinal Diseases and Treatments
  • Neuroscience and Neural Engineering
  • Retinal Imaging and Analysis
  • Glaucoma and retinal disorders
  • Photoreceptor and optogenetics research
  • Retinal and Macular Surgery

David R. Hinton has published in several notable scientific venues. Frequent publication outlets include:

  • Acta Neuropathologica
  • Translational Vision Science & Technology
  • Science Advances
  • Science Immunology
  • Stem Cell Reports

Notable recent papers authored or co-authored by David R. Hinton include:

  • Identification of early pericyte loss and vascular amyloidosis in Alzheimer's disease retina, 2020, Acta Neuropathologica
  • Retinal pathological features and proteome signatures of Alzheimer's disease, 2023, Acta Neuropathologica
  • One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration, 2021, Translational Vision Science & Technology
  • The Emerging Role of Senescence in Ocular Disease, 2020, Oxidative Medicine and Cellular Longevity
  • Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration, 2021, Proceedings of the National Academy of Sciences

Frequent collaborators in their research include:

  • Mark S. Humayun
  • Danhong Zhu
  • Anthony Rodriguez
  • Jane Lebkowski
  • Biju B. Thomas

Best Publications

  • Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes

    P F Lopez;B D Sippy;H M Lambert;A B Thach

  • Tumor necrosis factor identified in multiple sclerosis brain.

    F M Hofman;D R Hinton;K Johnson;J E Merrill

  • Optic-Nerve Degeneration in Alzheimer's Disease

    David R. Hinton;Alfredo A. Sadun;Janet C. Blanks;Carol A. Miller

  • MDR1 gene expression in brain of patients with medically intractable epilepsy.

    David M. Tishler;Kenneth I. Weinberg;David R. Hinton;Nicholas Barbaro

  • DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

    Hiroki Kaneko;Sami Dridi;Valeria Tarallo;Bradley D. Gelfand

  • DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

    Valeria Tarallo;Yoshio Hirano;Bradley D. Gelfand;Sami Dridi

  • The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

    J Li;M Ni;M Ni;B Lee;E Barron

  • Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

    Nay Wei Soong;David R. Hinton;Gino A Cortopassi;Norman Arnheim

  • Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer’s disease

    Yosef Koronyo;David Biggs;Ernesto Barron;David S. Boyer

  • Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor–positive human tumors

    Rizwan Masood;Jie Cai;Tong Zheng;D. Lynne Smith

  • Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain.

    F M Hofman;R I von Hanwehr;C A Dinarello;S B Mizel

  • Retinal pathology in Alzheimer's disease. I. Ganglion cell loss in foveal/parafoveal retina

    Janet C. Blanks;Yasuhiro Torigoe;David R. Hinton;Robert H.I. Blanks

  • Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice

    Jean E. Merrill;Dwight H. Kono;Julie Clayton;Dale G. Ando

  • Retinal ganglion cell degeneration in Alzheimer's disease.

    Janet C. Blanks;David R. Hinton;David R. Hinton;Alfredo A. Sadun;Carol A. Miller;Carol A. Miller

  • A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration

    Amir H. Kashani;Jane S. Lebkowski;Firas M. Rahhal;Robert L. Avery

  • Retinal pathology in Alzheimer's disease. II. Regional neuron loss and glial changes in GCL.

    Janet C. Blanks;Susan Y. Schmidt;Yasuhiro Torigoe;Kathryn V. Porrello

  • Post-traumatic proliferative vitreoretinopathy. The epidemiologic profile, onset, risk factors, and visual outcome.

    Jose A. Cardillo;J. Timothy Stout;Laurie LaBree;Stanley P. Azen

  • Assessment of visual impairment in patients with Alzheimer's disease.

    Alfredo A. Sadun;Mark Borchert;Edward DeVita;David R. Hinton

  • Primitive neuroectodermal tumors of the central nervous system.

    Laurence E. Becker;David Hinton

  • Transdifferentiated Retinal Pigment Epithelial Cells are Immunoreactive for Vascular Endothelial Growth Factor in Surgically Excised AgeRelated Macular Degeneration-Related Choroidal Neovascular Membranes.

    P F Lopez;B D Sippy;H M Lambert;A B Thach

Frequent Co-Authors

Stephen J. Ryan
Stephen J. Ryan University of Southern California
Stephen A. Stohlman
Stephen A. Stohlman Cleveland Clinic
Mark S. Humayun
Mark S. Humayun University of Southern California
Cornelia C. Bergmann
Cornelia C. Bergmann Cleveland Clinic
William T. Couldwell
William T. Couldwell University of Utah
Florence M. Hofman
Florence M. Hofman University of Southern California
Michael L.J. Apuzzo
Michael L.J. Apuzzo Yale University
Michael Koss
Michael Koss ETH Zurich
Gerald J. Chader
Gerald J. Chader University of Southern California
Parkash S. Gill
Parkash S. Gill University of Southern California

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