World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
99
Citations
29085
World Ranking
765
National Ranking
48

Medicine

D-Index
102
Citations
30449
World Ranking
7763
National Ranking
439

Overview

Klaus V. Toyka is affiliated with the University of Würzburg in Germany. Their research primarily spans the fields of Medicine and Neuroscience, with significant focus on Neurology, Molecular Biology, Physiology, Critical Care and Intensive Care Medicine, and Cellular and Molecular Neuroscience.

The scientist's work covers a range of topics, including:

  • Pain Mechanisms and Treatments
  • Intensive Care Unit Cognitive Disorders
  • Botulinum Toxin and Related Neurological Disorders
  • Hereditary Neurological Disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Acupuncture Treatment Research Studies

Toyka has published in several notable venues, most frequently in the International Journal of Molecular Sciences. Other publication venues include Research Square, Molecular Therapy, PLoS ONE, and Human Molecular Genetics.

Selected recent papers by Toyka include:

  • "Inflammatory Mechanisms in the Pathophysiology of Diabetic Peripheral Neuropathy (DN)-New Aspects," 2021, International Journal of Molecular Sciences
  • "Targeted rescue of synaptic plasticity improves cognitive decline in sepsis-associated encephalopathy," 2024, Molecular Therapy
  • "Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice," 2020, PLoS ONE
  • "Treatment-Induced Neuropathy in Diabetes (TIND)-Developing a Disease Model in Type 1 Diabetic Rats," 2021, International Journal of Molecular Sciences
  • "Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy," 2020, Human Molecular Genetics

The scientist frequently collaborates with other researchers, including:

  • Petra Baum
  • Matthias Blüher
  • Joseph Claßen
  • Joanna Kosacka
  • Marcin Nowicki

Best Publications

  • Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos

    Bertold Schrank;Rudolf Götz;Jennifer M. Gunnersen;Janice M. Ure

  • Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis.

    Harald H. Hofstetter;Saleh M. Ibrahim;Dirk Koczan;Niels Kruse

  • DEFECTIVE PROPAGATION OF SIGNALS GENERATED BY SYMPATHETIC NERVE STIMULATION IN THE LIVER OF CONNEXIN32-DEFICIENT MICE

    Eric Nelles;Christoph Butzler;Dirk Jung;Achim Temme

  • Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin.

    Dirk Montag;Karl Peter Giese;Udo Bartsch;Rudolf Martini

  • Axonal prion protein is required for peripheral myelin maintenance

    Juliane Bremer;Frank Baumann;Cinzia Tiberi;Carsten Wessig

  • CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation

    Ralf A. Linker;Mathias Mäurer;Stefanie Gaupp;Rudolf Martini

  • Hypermyelination and demyelinating peripheral neuropathy in Pmp22 -deficient mice

    Katrin Adlkofer;Rudolf Martini;Adriano Aguzzi;Jürgen Zielasek

  • Tumor Recurrence and Survival in Patients Treated for Thymomas and Thymic Squamous Cell Carcinomas: A Retrospective Analysis

    Philipp Ströbel;Andrea Bauer;Bernhard Puppe;Til Kraushaar

  • Immunopathogenesis and treatment of the Guillain-Barré syndrome--Part I.

    Hans‐Peter Hartung;Klaus V. Toyka;John D. Pollard;Graham K. Harvey

  • Animal models for autoimmune demyelinating disorders of the nervous system

    Ralf Gold;Hans-Peter Hartung;Klaus V Toyka

  • Differential expression of cytokines in painful and painless neuropathies

    Nurcan Üçeyler;Jan P. Rogausch;Klaus V. Toyka;Claudia Sommer

  • Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies

    R Martini;J Zielasek;K V Toyka;K P Giese

  • Structural Abnormalities and Deficient Maintenance of Peripheral Nerve Myelin in Mice Lacking the Gap Junction Protein Connexin 32

    Patrizia Anzini;Dirk H.-H. Neuberg;Melitta Schachner;Eric Nelles

  • Myasthenia gravis: Long‐term correlation of binding and bungarotoxin blocking antibodies against acetylcholine receptors with changes in disease severity

    Uwe A. Besinger;Klaus V. Toyka;Martina Hömberg;Kurt Heininger

  • A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis

    Günter Ochs;Richard D Penn;Michelle York;Ralf Giess

  • Intravenous immunoglobulin for myasthenia gravis

    Philippe Gajdos;Sylvie Chevret;Klaus V Toyka

  • Focal Hyperhidrosis: Effective Treatment With Intracutaneous Botulinum Toxin

    Markus Naumann;Uta Hofmann;Ilka Bergmann;Henning Hamm

  • A PD-1 polymorphism is associated with disease progression in multiple sclerosis.

    Antje Kroner;Matthias Mehling;Bernhard Hemmer;Peter Rieckmann

  • Paraneoplastic stiff-person syndrome: passive transfer to rats by means of IgG antibodies to amphiphysin

    Claudia Sommer;Andreas Weishaupt;Jörg Brinkhoff;Lydia Biko

  • Inflammatory Mediators in Demyelinating Disorders of the Cns and Pns

    Hans-Peter Hartung;Stefan Jung;Guido Stoll;Jürgen Zielasek

  • Production of nitrite by neonatal rat microglial cells/brain macrophages.

    Jürgen Zielasek;Maria Tausch;Klaus V. Toyka;Hans-Peter Hartung

Frequent Co-Authors

Ralf Gold
Ralf Gold Ruhr University Bochum
Claudia Sommer
Claudia Sommer University of Würzburg
Hans-Peter Hartung
Hans-Peter Hartung Heinrich Heine University Düsseldorf
Ralf Gold
Ralf Gold Ruhr University Bochum
Rudolf Martini
Rudolf Martini University of Würzburg
Michael Sendtner
Michael Sendtner University of Würzburg
Ueli Suter
Ueli Suter École Polytechnique Fédérale de Lausanne
Hans Lassmann
Hans Lassmann Medical University of Vienna
Reinhard Hohlfeld
Reinhard Hohlfeld Ludwig-Maximilians-Universität München
Ingo Bechmann
Ingo Bechmann Leipzig University

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