D-Index & Metrics Best Publications
Immunology
Germany
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 96 Citations 28,204 313 World Ranking 519 National Ranking 26
Medicine D-index 100 Citations 33,987 452 World Ranking 4947 National Ranking 252

Research.com Recognitions

Awards & Achievements

2023 - Research.com Immunology in Germany Leader Award

2005 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Disease

Immunology, Multiple sclerosis, Antibody, Antigen and Molecular biology are his primary areas of study. His Immunology and Glatiramer acetate, Myelin oligodendrocyte glycoprotein, Interferon, T cell and Cytokine investigations all form part of his Immunology research activities. His Cytokine research is multidisciplinary, incorporating perspectives in Tumor necrosis factor alpha, Myositis, Autoimmune disease, Genetic enhancement and Immunopathology.

The study incorporates disciplines such as Immunophenotyping, Central nervous system and Immune system, Immunotherapy in addition to Multiple sclerosis. His study looks at the relationship between Antibody and topics such as Pathology, which overlap with Apoptosis. His biological study deals with issues like Cytotoxic T cell, which deal with fields such as Inflammation, Programmed cell death, Inclusion body myositis and Fas receptor.

His most cited work include:

  • Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring (382 citations)
  • Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives. (332 citations)
  • Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells. (282 citations)

What are the main themes of his work throughout his whole career to date?

Reinhard Hohlfeld mainly investigates Multiple sclerosis, Immunology, Internal medicine, Pathology and Antibody. Reinhard Hohlfeld has researched Multiple sclerosis in several fields, including Disease, Neuroscience and Intensive care medicine. His study in Antigen, Myasthenia gravis, T cell, Immune system and Autoantibody is carried out as part of his Immunology studies.

His research on T cell also deals with topics like

  • Cytotoxic T cell and related CD8, Molecular biology and Cell biology,
  • T-cell receptor most often made with reference to Virology. In his study, which falls under the umbrella issue of Internal medicine, Discontinuation and Neurology is strongly linked to Fingolimod. His research in Antibody focuses on subjects like Receptor, which are connected to Tumor necrosis factor alpha.

He most often published in these fields:

  • Multiple sclerosis (51.67%)
  • Immunology (42.75%)
  • Internal medicine (20.07%)

What were the highlights of his more recent work (between 2013-2021)?

  • Multiple sclerosis (51.67%)
  • Immunology (42.75%)
  • Internal medicine (20.07%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Multiple sclerosis, Immunology, Internal medicine, Pathology and In patient. He studies Myelin oligodendrocyte glycoprotein, a branch of Multiple sclerosis. His study in Autoantibody, Autoimmunity, Experimental autoimmune encephalomyelitis, Immune system and Antibody falls under the purview of Immunology.

His Autoimmunity research includes themes of Mutation, T cell and B cell. His biological study spans a wide range of topics, including Penetrance, Fingolimod, Oncology and Endocrinology. As part of the same scientific family, he usually focuses on Pathology, concentrating on T-cell receptor and intersecting with Brain lesions, Alpha chain, Single-cell analysis and Peptide sequence.

Between 2013 and 2021, his most popular works were:

  • γ-secretase directly sheds the survival receptor BCMA from plasma cells (134 citations)
  • From classic to spontaneous and humanized models of multiple sclerosis: impact on understanding pathogenesis and drug development. (98 citations)
  • Cerebrospinal Fluid JC Virus Antibody Index for Diagnosis of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy (71 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Disease

His primary scientific interests are in Multiple sclerosis, Immunology, Pathology, Receptor and Myelin oligodendrocyte glycoprotein. His study in Multiple sclerosis is interdisciplinary in nature, drawing from both Mutation, Interferon, Phenotype, CD8 and Disease. Immunology is represented through his Experimental autoimmune encephalomyelitis, Autoimmunity, Immunoglobulin M, Affinity maturation and Cytidine deaminase research.

He interconnects Complementarity determining region, Molecular biology, T-cell receptor, B-Cell Maturation Antigen and Bone marrow in the investigation of issues within Receptor. His work carried out in the field of Myelin oligodendrocyte glycoprotein brings together such families of science as Antibody, Neuromyelitis optica, Flow cytometry, Atrophy and Subclinical infection. His Internal medicine study combines topics from a wide range of disciplines, such as Extracellular, Endocrinology, Cellular differentiation and Antigen.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis

Ludwig Kappos;Ernst Wilhelm Radue;Paul O'Connor;Chris Polman.
The New England Journal of Medicine (2010)

2939 Citations

Polymyositis and Dermatomyositis

Marinos C Dalakas;Reinhard Hohlfeld.
(1988)

1724 Citations

Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction

Holger Babbe;Axel Roers;Ari Waisman;Hans Lassmann.
Journal of Experimental Medicine (2000)

1274 Citations

BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma

Markus Krumbholz;Diethilde Theil;Tobias Derfuss;Andreas Rosenwald.
Journal of Experimental Medicine (2005)

628 Citations

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice.

Kerstin Berer;Lisa Ann Gerdes;Egle Cekanaviciute;Xiaoming Jia.
Proceedings of the National Academy of Sciences of the United States of America (2017)

597 Citations

MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47

Andreas Junker;Markus Krumbholz;Sylvia Eisele;Hema Mohan.
Brain (2009)

586 Citations

Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment.

Markus Krumbholz;Diethilde Theil;Sabine Cepok;Bernhard Hemmer.
Brain (2006)

571 Citations

BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells?

Christine Stadelmann;Martin Kerschensteiner;Thomas Misgeld;Wolfgang Brück.
Brain (2002)

562 Citations

Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives.

R Hohlfeld.
Brain (1997)

511 Citations

Multiple sclerosis: Brain-infiltrating CD8(+) T cells persist as clonal expansions in the cerebrospinal fluid and blood

Christian Skulina;Stephan Schmidt;Klaus Dornmair;Holger Babbe.
Proceedings of the National Academy of Sciences of the United States of America (2004)

482 Citations

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