H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 91 Citations 29,660 215 World Ranking 407 National Ranking 18
Medicine D-index 94 Citations 31,456 238 World Ranking 4854 National Ranking 221

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antibody

His primary areas of study are Immunology, T cell, Experimental autoimmune encephalomyelitis, Major histocompatibility complex and Myelin. His Immunology study deals with Myelin basic protein intersecting with Epitope and Cell culture. Hartmut Wekerle combines subjects such as Encephalomyelitis, T lymphocyte and Monoclonal antibody with his study of T cell.

The Experimental autoimmune encephalomyelitis study combines topics in areas such as Autoimmune disease, Immune tolerance, Glatiramer acetate, Adoptive cell transfer and Autoimmunity. His biological study spans a wide range of topics, including Interferon and Cell biology. The various areas that Hartmut Wekerle examines in his Myelin study include Inflammation and Astrocyte.

His most cited work include:

  • The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis (836 citations)
  • Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination (796 citations)
  • Astrocytes present myelin basic protein to encephalitogenic T-cell lines. (706 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Immunology, T cell, Multiple sclerosis, Antigen and Experimental autoimmune encephalomyelitis. His Immunology study frequently draws connections to other fields, such as Central nervous system. His T cell research is multidisciplinary, incorporating elements of Cytotoxic T cell, Myelin basic protein and Molecular biology.

His Multiple sclerosis study combines topics in areas such as Disease, Pathogenesis, Pathology, Antibody and Immunotherapy. His research integrates issues of Antigen presentation, Lymphocyte and Virology in his study of Antigen. His study looks at the relationship between Experimental autoimmune encephalomyelitis and topics such as Encephalomyelitis, which overlap with Microglia.

He most often published in these fields:

  • Immunology (66.25%)
  • T cell (29.72%)
  • Multiple sclerosis (22.91%)

What were the highlights of his more recent work (between 2011-2020)?

  • Immunology (66.25%)
  • Multiple sclerosis (22.91%)
  • Autoimmunity (12.38%)

In recent papers he was focusing on the following fields of study:

Hartmut Wekerle mainly investigates Immunology, Multiple sclerosis, Autoimmunity, Immune system and Experimental autoimmune encephalomyelitis. His Immunology study frequently draws parallels with other fields, such as Central nervous system. The Multiple sclerosis study combines topics in areas such as Myelin basic protein, CD8, T-cell receptor and Pathology.

His Experimental autoimmune encephalomyelitis study incorporates themes from Transgenic Model and Adoptive cell transfer. His research in Antigen intersects with topics in Myelin oligodendrocyte glycoprotein and T cell, Antigen-presenting cell. His work deals with themes such as Cytotoxic T cell and Cell biology, which intersect with T cell.

Between 2011 and 2020, his most popular works were:

  • Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice (317 citations)
  • T cells become licensed in the lung to enter the central nervous system (268 citations)
  • MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies (228 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

Hartmut Wekerle mostly deals with Immunology, Antigen, Experimental autoimmune encephalomyelitis, T cell and Autoimmune disease. His Immunology study frequently draws connections to adjacent fields such as Central nervous system. His work carried out in the field of Antigen brings together such families of science as Amyloid precursor protein secretase, B-Cell Maturation Antigen, Cellular differentiation and Endocrinology.

Hartmut Wekerle has included themes like Pathology and Cell biology in his T cell study. Hartmut Wekerle has researched Autoimmune disease in several fields, including Myelin basic protein, Glatiramer acetate and Autoimmunity, Immune system. He combines subjects such as Blood–brain barrier, Aquaporin 4, Astrocyte, Antibody and Immunotherapy with his study of Multiple sclerosis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

Avraham Ben-Nun;Hartmut Wekerle;Irun R. Cohen.
European Journal of Immunology (1981)

1338 Citations

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

Kerstin Berer;Marsilius Mues;Michail Koutrolos;Zakeya Al Rasbi.
Nature (2011)

1023 Citations

Cellular immune reactivity within the CNS

H. Wekerle;C. Linington;H. Lassmann;R. Meyermann.
Trends in Neurosciences (1986)

950 Citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines.

Adriano Fontana;Walter Fierz;Hartmut Wekerle.
Nature (1984)

924 Citations

Vaccination against autoimmune encephalomyelitis with T-lymphocite line cells reactive against myelin basic protein

Avraham Ben-Nun;Hartmut Wekerle;Irun R. Cohen.
Nature (1981)

782 Citations

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

Ingo Bartholomäus;Naoto Kawakami;Francesca Odoardi;Christian Schläger.
Nature (2009)

717 Citations

BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma

Markus Krumbholz;Diethilde Theil;Tobias Derfuss;Andreas Rosenwald.
Journal of Experimental Medicine (2005)

597 Citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

W Fierz;B Endler;K Reske;H Wekerle.
Journal of Immunology (1985)

536 Citations

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice.

Deming Sun;John N. Whitaker;Zhigang Huang;Di Liu.
Journal of Immunology (2001)

534 Citations

Induction of MHC class I genes in neurons

Harald Neumann;Adolfo Cavalie;Dieter E. Jenne;Hartmut Wekerle.
Science (1995)

522 Citations

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