World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
73
Citations
16377
World Ranking
2157
National Ranking
1047

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Thomas E. Lane is affiliated with the University of California, Irvine in the United States. Their research activities span multiple fields, predominantly Medicine, Neuroscience, and Immunology and Microbiology. Within these fields, their work focuses extensively on subfields such as Neurology, Immunology, Infectious Diseases, Molecular Biology, and Developmental Neuroscience.

The scientist's research covers several main topics including:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Long-Term Effects of COVID-19
  • Immune cells in cancer
  • Neurogenesis and neuroplasticity mechanisms
  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction

Among the recent publications involving Thomas E. Lane are:

  • Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system, 2020, Glia
  • Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant, 2020, Neurobiology of Disease
  • Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development, 2020, Cell Reports
  • EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria, 2020, PLoS Pathogens
  • Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling, 2022, Neuron

Thomas E. Lane frequently publishes in specific venues, such as:

  • Glia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuron
  • Journal of Virology
  • The Journal of Immunology

Collaborations form an integral part of the scientist's research approach. Frequent coauthors include Amber R. Syage, Kim N. Green, Yu-Ting Cheng, Craig M. Walsh, and Collin Pachow. These collaborations have contributed to advancing knowledge in their fields of study.

In recognition of their contributions, Thomas E. Lane was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • IFN-γ-Inducible Protein 10 (IP-10; CXCL10)-Deficient Mice Reveal a Role for IP-10 in Effector T Cell Generation and Trafficking

    Jennifer H. Dufour;Michelle Dziejman;Michael T. Liu;Josephine H. Leung

  • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.

    Jean E. Merrill;Louis J. Ignarro;Michael P. Sherman;Judy Melinek

  • Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion.

    Laura J. Cliffe;Neil E Humphreys;Neil E Humphreys;Thomas E. Lane;Thomas E. Lane;Chris S. Potten;Chris S. Potten

  • Coronavirus infection of the central nervous system: host–virus stand-off

    Cornelia C. Bergmann;Thomas E. Lane;Stephen A. Stohlman

  • The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function

    Samuel E. Marsh;Edsel M. Abud;Anita Lakatos;Alborz Karimzadeh

  • Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut

    Janet Z. Liu;Stefan Jellbauer;Adam J. Poe;Vivian Ton

  • The Th17-ELR+ CXC Chemokine Pathway Is Essential for the Development of Central Nervous System Autoimmune Disease

    Thaddeus Carlson;Mark Kroenke;Praveen Rao;Thomas E. Lane

  • Cutting edge: The T cell chemoattractant IFN-inducible protein 10 is essential in host defense against viral-induced neurologic disease

    Michael T. Liu;Benjamin P. Chen;Patricia Oertel;Michael J. Buchmeier

  • Neutralization of the Chemokine CXCL10 Reduces Inflammatory Cell Invasion and Demyelination and Improves Neurological Function in a Viral Model of Multiple Sclerosis

    Michael T. Liu;Hans S. Keirstead;Thomas E. Lane

  • A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination.

    Thomas E. Lane;Michael T. Liu;Benjamin P. Chen;Valérie C. Asensio

  • Blocking Chemokine Responsive to γ–2/Interferon (IFN)-γ Inducible Protein and Monokine Induced by IFN-γ Activity In Vivo Reduces the Pathogenetic but not the Antiviral Potential of Hepatitis B Virus–specific Cytotoxic T Lymphocytes

    Kazuhiro Kakimi;Thomas E. Lane;Stefan Wieland;Valerie C. Asensio

  • Dynamic regulation of alpha- and beta-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease.

    Thomas E. Lane;Valérie C. Asensio;Naichen Yu;Alyssa D. Paoletti

  • Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis

    Kevin S. Carbajal;Christopher Schaumburg;Robert Strieter;Joy Kane

  • Inflammation induced by infection potentiates tau pathological features in transgenic mice.

    Michael Sy;Masashi Kitazawa;Rodrigo Medeiros;Lucia Whitman

  • G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands.

    Anja Köhler;Katia De Filippo;Mike Hasenberg;Cindy van den Brandt

  • CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis

    LiPing Liu;Abdelmadjid Belkadi;Lindsey Darnall;Taofang Hu

  • Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic Mice

    Josephine Herz;Pascal Sabellek;Thomas E. Lane;Matthias Gunzer

  • Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha.

    Iain L Campbell;Thomas Krucker;Scott Steffensen;Yvette Akwa

  • Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury.

    Rafael Gonzalez;Janette Glaser;Michael T Liu;Thomas E Lane

  • The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.

    Gurkan Mollaoglu;Alex Jones;Sarah J. Wait;Anandaroop Mukhopadhyay

  • Coxsackievirus B3-Induced Myocarditis : Perforin Exacerbates Disease, But Plays No Detectable Role in Virus Clearance

    John R. Gebhard;Christopher M. Perry;Stephanie Harkins;Thomas Lane

Frequent Co-Authors

Michael J. Buchmeier
Michael J. Buchmeier University of California, Irvine
Sean Ekins
Sean Ekins University of Arizona
Vijay S. Pande
Vijay S. Pande Stanford University
Ryan M. O'Connell
Ryan M. O'Connell University of Utah
Richard M. Ransohoff
Richard M. Ransohoff Harvard University
Howard S. Fox
Howard S. Fox University of Nebraska Medical Center
Iain L. Campbell
Iain L. Campbell University of Sydney
Daniel J. J. Carr
Daniel J. J. Carr University of Oklahoma Health Sciences Center
Henry N. Chapman
Henry N. Chapman Universität Hamburg
Sebastian Doniach
Sebastian Doniach Stanford University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Students interested in Immunology often explore various healthcare-related online degrees to complement their scientific knowledge. For example, those considering advanced clinical roles might pursue nurse practitioner programs. The cheapest pmhnp certificate programs provide cost-effective pathways to specialize in psychiatric mental health nursing, a field closely aligned with immunological aspects of mental health.

Understanding salary variations can also help students choose a suitable specialty. The comprehensive overview of dnp salary by specialty offers valuable insights into earning potential across different advanced practice nursing fields, which is crucial for long-term career planning.

For nurses looking to specialize further, obtaining an acute care np certification represents an important step. This certification equips practitioners to provide high-level care to seriously ill patients, often involving immunology-related conditions.

Additionally, accelerated study options such as the nurse practitioner accelerated program can help qualified students fast-track their education and enter the workforce more quickly, making it an attractive choice for those eager to advance their careers.

Best Scientists Citing Thomas E. Lane

Trending Scientists