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Manuel A. Friese

Manuel A. Friese

D-Index & Metrics

Immunology

D-Index
54
Citations
16969
World Ranking
3841
National Ranking
263

Overview

Manuel A. Friese is a researcher affiliated with Universität Hamburg in Germany. Their work primarily intersects the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a significant focus on Immunology, Neurology, and Molecular Biology. Additional areas of interest include Pathology and Forensic Medicine as well as Physiology.

Their research explores various topics, including:

  • Multiple Sclerosis Research Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Autoimmune Neurological Disorders and Treatments
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Long-Term Effects of COVID-19
  • Alzheimer's disease research and treatments

Some of the recent papers reflecting the scope of their work are:

  • Frequent neurocognitive deficits after recovery from mild COVID-19, 2020, Brain Communications
  • The immunology of multiple sclerosis, 2022, Nature Reviews. Immunology
  • The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2, 2022, Stem Cell Reports
  • Ferroptosis in health and disease, 2024, Redox Biology
  • Rituximab Treatment and Long-term Outcome of Patients With Autoimmune Encephalitis, 2021, Neurology Neuroimmunology & Neuroinflammation

The scientist frequently collaborates with a group of colleagues, including:

  • Marcel S. Woo
  • Christoph Heesen
  • Friedemann Paul
  • Jana K. Sonner
  • Jan Broder Engler

Their publications appear predominantly in select scientific journals. The top venues for their work are:

  • Neurology Neuroimmunology & Neuroinflammation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Brain Communications
  • Cell

Best Publications

  • Immunopathology of multiple sclerosis

    Calliope A. Dendrou;Lars Fugger;Lars Fugger;Manuel A. Friese

  • Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.

    John S. Tzartos;Manuel A. Friese;Matthew J. Craner;Jackie Palace

  • N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes

    Sarosh R. Irani;Katarzyna Bera;Patrick Waters;Luigi Zuliani

  • Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

    Manuel A Friese;Benjamin Schattling;Lars Fugger

  • A vaccine targeting mutant IDH1 induces antitumour immunity

    Theresa Schumacher;Lukas Bunse;Stefan Pusch;Felix Sahm

  • Neuronal vulnerability and multilineage diversity in multiple sclerosis

    Lucas Schirmer;Dmitry Velmeshev;Staffan Holmqvist;Max Kaufmann

  • Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.

    Mathias Gelderblom;Anna Weymar;Christian Bernreuther;Joachim Velden

  • Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.

    Manuel A Friese;Matthew J Craner;Ruth Etzensperger;Sandra Vergo

  • RNA Interference Targeting Transforming Growth Factor-β Enhances NKG2D-Mediated Antiglioma Immune Response, Inhibits Glioma Cell Migration and Invasiveness, and Abrogates Tumorigenicity In vivo

    Manuel A. Friese;Jörg Wischhusen;Wolfgang Wick;Markus Weiler

  • Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

    Manuel A. Friese;Lars Fugger

  • MICA/NKG2D-Mediated Immunogene Therapy of Experimental Gliomas

    Manuel A. Friese;Michael Platten;Stefan Z. Lutz;Ulrike Naumann

  • The immunology of multiple sclerosis

    Unknown

  • TGF-β and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells

    Günter Eisele;Jörg Wischhusen;Michel Mittelbronn;Richard Meyermann

  • Pathogenic CD8(+) T cells in multiple sclerosis.

    Manuel A. Friese;Lars Fugger;Lars Fugger

  • T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides

    Maria Harkiolaki;Samantha L. Holmes;Samantha L. Holmes;Pia Svendsen;Jon W. Gregersen

  • Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

    Manuel A Friese;Karen B Jakobsen;Lone Friis;Ruth Etzensperger

  • Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.

    Sandra Vergo;Matthew J. Craner;Ruth Etzensperger;Kathrine Attfield

  • The value of animal models for drug development in multiple sclerosis.

    Manuel A. Friese;Xavier Montalban;Nick Willcox;John I. Bell

  • TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.

    Benjamin Schattling;Karin Steinbach;Karin Steinbach;Edda Thies;Martin Kruse

  • HLA-E protects glioma cells from NKG2D-mediated immune responses in vitro: implications for immune escape in vivo.

    Jörg Wischhusen;Manuel A. Friese;Manuel A. Friese;Michel Mittelbronn;Richard Meyermann

  • Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life

    Renée R C E Schreurs;Martin E Baumdick;Adrian F Sagebiel;Max Kaufmann

  • Multiple sclerosis : T-cell receptor expression in distinct brain regions. Commentary

    Manuel A. Friese;Lars Fugger;Andreas Junker;Jana Ivanidze

Frequent Co-Authors

Lars Fugger
Lars Fugger University of Oxford
Peter F. Zipfel
Peter F. Zipfel Friedrich Schiller University Jena
Michael Weller
Michael Weller University of Zurich
Seppo Meri
Seppo Meri University of Helsinki
Doron Merkler
Doron Merkler University of Geneva
Alexander Steinle
Alexander Steinle Goethe University Frankfurt
Margaret M. Esiri
Margaret M. Esiri University of Oxford
Petra C. Arck
Petra C. Arck Universität Hamburg
Christian Gerloff
Christian Gerloff University Medical Center Hamburg-Eppendorf
Marc Freichel
Marc Freichel Heidelberg University

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