World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
79
Citations
28407
World Ranking
1665
National Ranking
144

Medicine

D-Index
79
Citations
28527
World Ranking
17412
National Ranking
1576

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Lars Fugger is affiliated with the University of Oxford in the United Kingdom and has a research focus spanning several disciplines within biomedical science. Their main fields of study include Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these fields, more detailed subfields of study include Immunology, Genetics, Neurology, Molecular Biology, and Pathology and Forensic Medicine.

Their research topics cover a range of specialized areas including Multiple Sclerosis Research Studies, T-cell and B-cell Immunology, Neuroinflammation and Neurodegeneration Mechanisms, Peripheral Neuropathies and Disorders, Yersinia bacterium and plague research, Zoonotic diseases and public health, and the function and interaction of immune cells.

Fugger's recent publications reflect this focus. Among them are:

  • Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases, 2020, Cell
  • The immunology of multiple sclerosis, 2022, Nature reviews. Immunology
  • Inflammation-related plasma and CSF biomarkers for multiple sclerosis, 2020, Proceedings of the National Academy of Sciences
  • Identification of early neurodegenerative pathways in progressive multiple sclerosis, 2022, Nature Neuroscience
  • The selection landscape and genetic legacy of ancient Eurasians, 2024, Nature

Frequent co-authors in Fugger's work include:

  • Kathrine E. Attfield
  • Lise Torp Jensen
  • Astrid K. N. Iversen
  • Evan K. Irving-Pease
  • Eske Willerslev

Fugger's publications commonly appear in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature, Nature reviews. Immunology, Proceedings of the National Academy of Sciences, and Cell. These venues correspond to the interdisciplinary and immunology-related nature of their research.

Lars Fugger has been recognized as a Fellow of The Academy of Medical Sciences, United Kingdom. The fellowship acknowledges contributions to the advancement of medical science.

Best Publications

  • Immunopathology of multiple sclerosis

    Calliope A. Dendrou;Lars Fugger;Lars Fugger;Manuel A. Friese

  • Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.

    John S. Tzartos;Manuel A. Friese;Matthew J. Craner;Jackie Palace

  • The Human Cell Atlas

    Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit

  • Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

    Øyvind Molberg;Stephen N. Mcadam;Roman Körner;Hanne Quarsten

  • Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

    Roland Tisch;Xiao Dong Yang;Steven M. Singer;Roland S. Liblau

  • Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

    Manuel A Friese;Benjamin Schattling;Lars Fugger

  • HLA variation and disease

    Calliope A. Dendrou;Jan Petersen;Jamie Rossjohn;Jamie Rossjohn;Jamie Rossjohn;Lars Fugger

  • A functional and structural basis for TCR cross-reactivity in multiple sclerosis

    Heather L.E. Lang;Helle Jacobsen;Helle Jacobsen;Shinji Ikemizu;Christina Andersson;Christina Andersson

  • MHC class II proteins and disease: a structural perspective

    E Y Jones;L Fugger;L Fugger;J L Strominger;C Siebold

  • Mice lacking all conventional MHC class II genes.

    Lars Madsen;Nathalie Labrecque;Jan Engberg;Andrée Dierich

  • Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.

    Manuel A Friese;Matthew J Craner;Ruth Etzensperger;Sandra Vergo

  • TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

    Adam P. Gregory;Calliope A. Dendrou;Kathrine E. Attfield;Aiden Haghikia;Aiden Haghikia

  • Constitutively active Lck kinase in T cells drives antigen receptor signal transduction.

    Konstantina Nika;Cristiana Soldani;Mogjiborahman Salek;Wolfgang Paster

  • Class II HLA interactions modulate genetic risk for multiple sclerosis

    L Moutsianas;L Jostins;A H Beecham;A T Dilthey

  • Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    Jenny C. Taylor;Jenny C. Taylor;Hilary C. Martin;Stefano Lise;John Broxholme

  • A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor.

    Lars S. Madsen;Ellen Christina Andersson;Liselotte Jansson;Michelle Krogsgaard

  • Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases.

    Lars Fugger;Lars Fugger;Lise Torp Jensen;Lise Torp Jensen;Jamie Rossjohn;Jamie Rossjohn;Jamie Rossjohn

  • Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

    Manuel A. Friese;Lars Fugger

  • Inherited deficiency of mannan-binding lectin-associated serine protease 2.

    Kristian Stengaard-Pedersen;Steffen Thiel;Mihaela Gadjeva;Mette Møller-Kristensen

  • Control of hypothalamic orexin neurons by acid and CO2

    Rhîannan H. Williams;Lise T. Jensen;Alex Verkhratsky;Lars Fugger

  • Tandem-Pore K+ Channels Mediate Inhibition of Orexin Neurons by Glucose

    Denis Burdakov;Lise T. Jensen;Haris Alexopoulos;Rhiannan H. Williams

  • Predominant selection of T cells specific for the glycosylated collagen type II epitope (263–270) in humanized transgenic mice and in rheumatoid arthritis

    Johan Bäcklund;Stefan Carlsen;Torsten Höger;Björn Holm

Frequent Co-Authors

Manuel A. Friese
Manuel A. Friese Universität Hamburg
Jamie Rossjohn
Jamie Rossjohn Monash University
John I. Bell
John I. Bell Ellison Institute of Technology
Arne Svejgaard
Arne Svejgaard University of Copenhagen
Niels Morling
Niels Morling University of Copenhagen
Niels Ødum
Niels Ødum University of Copenhagen
Denis Burdakov
Denis Burdakov ETH Zurich
Gil McVean
Gil McVean University of Oxford
Jan Gerstoft
Jan Gerstoft Rigshospitalet
Stephen R. Holdsworth
Stephen R. Holdsworth Monash University

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