World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
94
Citations
27727
World Ranking
940
National Ranking
515

Medicine

D-Index
94
Citations
28324
World Ranking
10589
National Ranking
5444

Overview

Robert S. Klein is affiliated with Washington University in St. Louis in the United States. Their research spans the fields of Medicine and Neuroscience, with significant focus on several key subfields including Neurology, Immunology, Infectious Diseases, Molecular Biology, and Public Health, Environmental and Occupational Health.

The scientist's main topics of study include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Mosquito-borne diseases and control
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Immune cells in cancer
  • Interferon and immune responses

Robert S. Klein has contributed to a range of recent publications, notable for their impact and topical relevance. Some highlighted papers are:

  • How COVID-19 Affects the Brain, 2021, published in JAMA Psychiatry
  • Sex differences in cancer mechanisms, 2020, published in Biology of Sex Differences
  • A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters, 2021, published in Cell Reports
  • Neuroinflammation and COVID-19, 2022, published in Current Opinion in Neurobiology
  • Therapeutic enhancement of blood-brain and blood-tumor barriers permeability by laser interstitial thermal therapy, 2020, published in Neuro-Oncology Advances

The scientist regularly publishes in several academic venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroimmunology
  • Frontiers in Immunology
  • Nature Immunology
  • Cell Reports

Frequent collaborators of Robert S. Klein include:

  • Allison Soung
  • Michael Diamond
  • Matthew D. Cain
  • Abigail Vanderheiden
  • Xiaoping Jiang

Best Publications

  • Oral candidiasis in high-risk patients as the initial manifestation of the acquired immunodeficiency syndrome.

    Robert S. Klein;Carol A. Harris;Catherine Butkus Small;Bernice Moll

  • Transmission of the human immunodeficiency virus.

    Gerald H. Friedland;Robert S. Klein

  • Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise.

    Jonathan J. Miner;Bin Cao;Jennifer Govero;Amber M. Smith

  • Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2)

    Leonid Izikson;Robyn S. Klein;Israel F. Charo;Howard L. Weiner

  • A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors

    Joshua B. Rubin;Andrew L. Kung;Robyn S. Klein;Jennifer A. Chan

  • A complement–microglial axis drives synapse loss during virus-induced memory impairment

    Michael J. Vasek;Charise Garber;Denise Dorsey;Douglas M. Durrant;Douglas M. Durrant

  • Acquired immunodeficiency syndrome. Ophthalmic manifestations in ambulatory patients.

    Paul R. Rosenberg;Alan E. Uliss;Gerald H. Friedland;Carol A. Harris

  • PCR detection of human papillomavirus: comparison between MY09/MY11 and GP5+/GP6+ primer systems.

    Weimin Qu;Gang Jiang;Yvette Cruz;Chee Jen Chang

  • Neuronal CXCL10 Directs CD8+ T-Cell Recruitment and Control of West Nile Virus Encephalitis

    Robyn S. Klein;Eugene Lin;Bo Zhang;Andrew D. Luster

  • Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction.

    Qiang Lu;Edna E. Sun;Robyn S. Klein;John G. Flanagan

  • Immunodeficiency in female sexual partners of men with the acquired immunodeficiency syndrome.

    Carol Harris;Catherine Butkus Small;Robert S. Klein;Gerald H. Friedland

  • Quantification of increased cellularity during inflammatory demyelination

    Yong Wang;Qing Wang;Justin P. Haldar;Fang-Cheng Yeh

  • COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital.

    Kiran T Thakur;Emily Happy Miller;Michael D Glendinning;Osama Al-Dalahmah

  • How COVID-19 Affects the Brain.

    Maura Boldrini;Peter D. Canoll;Robyn S. Klein

  • SDF-1α induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells

    Robyn S. Klein;Joshua B. Rubin;Hilary D. Gibson;Elliot N. DeHaan

  • High risk of human papillomavirus infection and cervical squamous intraepithelial lesions among women with symptomatic human immunodeficiency virus infection.

    Sten H. Vermund;Karen F. Kelley;Robert S. Klein;Anat R. Feingold

  • Sex differences in cancer mechanisms.

    Joshua B. Rubin;Joseph S. Lagas;Lauren Broestl;Jasmin Sponagel

  • BDNF stimulates migration of cerebellar granule cells

    Paul R. Borghesani;Jean Michel Peyrin;Robyn Klein;Joshua Rubin

  • TREM2 regulates microglial cell activation in response to demyelination in vivo

    Claudia Cantoni;Bryan Bollman;Danilo Licastro;Mingqiang Xie

  • The blood-brain barrier, chemokines and multiple sclerosis

    David W. Holman;Robyn S. Klein;Richard M. Ransohoff

  • Changes in B- and T-Lymphocyte and Chemokine Levels With Rituximab Treatment in Multiple Sclerosis

    Laura Piccio;Robert T. Naismith;Kathryn Trinkaus;Robyn S. Klein

  • Detecting axon damage in spinal cord from a mouse model of multiple sclerosis

    Joong Hee Kim;Matthew D. Budde;Hsiao-Fang Liang;Robyn S. Klein

Frequent Co-Authors

Michael S. Diamond
Michael S. Diamond Washington University in St. Louis
Gerald Friedland
Gerald Friedland Yale University
Jack D. Sobel
Jack D. Sobel Wayne State University
Kenneth H. Mayer
Kenneth H. Mayer Harvard Medical School
Anne H. Cross
Anne H. Cross Washington University in St. Louis
David Vlahov
David Vlahov Yale University
Denise J. Jamieson
Denise J. Jamieson Emory University
Franklin D. Lowy
Franklin D. Lowy Columbia University
Andrew D. Luster
Andrew D. Luster Harvard University
Susan Cu-Uvin
Susan Cu-Uvin Brown University

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