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Immunology

D-Index
117
Citations
45272
World Ranking
367
National Ranking
232

Overview

Howard A. Young is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with significant contributions in subfields such as Immunology, Molecular Biology, Oncology, Infectious Diseases, and Epidemiology.

Their work extensively covers topics including Immune Cell Function and Interaction, T-cell and B-cell Immunology, Cytokine Signaling Pathways and Interactions, Reproductive System and Pregnancy, Systemic Lupus Erythematosus Research, interferon and immune responses, and Liver Diseases and Immunity.

Recent publications include:

  • "Cytokines: From Clinical Significance to Quantification", 2021, Advanced Science
  • "The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge", 2020, Nature Immunology
  • "Lessons learned: new insights on the role of cytokines in COVID-19", 2021, Nature Immunology
  • "Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients", 2020, Journal of Clinical Investigation
  • "Multi-omics: Differential expression of IFN-γ results in distinctive mechanistic features linking chronic inflammation, gut dysbiosis, and autoimmune diseases", 2020, Journal of Autoimmunity

Frequent co-authors collaborating with Howard A. Young include:

  • Julio C. Valencia
  • M. Eric Gershwin
  • Enitome E. Bafor
  • Patrick S.C. Leung
  • John M. Fenimore

The scholar has published frequently in the following venues:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Frontiers in Immunology
  • Journal of Autoimmunity
  • The Journal of Immunology
  • Nature Immunology

Best Publications

  • Interleukin-1 polymorphisms associated with increased risk of gastric cancer

    Emad M. El-Omar;Emad M. El-Omar;Mary Carrington;Wong Ho Chow;Kenneth E.L. McColl

  • Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression.

    Rosalba Salcedo;Maria Lourdes Ponce;Howard A. Young;Ken Wasserman

  • INDOLEAMINE 2,3-DIOXYGENASE PRODUCTION BY HUMAN DENDRITIC CELLS RESULTS IN THE INHIBITION OF T CELL PROLIFERATION

    Patrick Hwu;Mark X. Du;Réjean Lapointe;My Do

  • CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

    Craig B. Thompson;Tullia Lindsten;Jeffrey A. Ledbetter;Steven L. Kunkel

  • The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

    Ronald W. Ellis;Deborah DeFeo;Thomas Y. Shih;Matthew A. Gonda

  • Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Induce Expression of CXCR4 on Human Endothelial Cells: In Vivo Neovascularization Induced by Stromal-Derived Factor-1α

    Rosalba Salcedo;Ken Wasserman;Howard A. Young;Michael C. Grimm

  • Cytokines: From Clinical Significance to Quantification.

    Chao Liu;Dewei Chu;Kourosh Kalantar‐Zadeh;Jacob George

  • Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection.

    Thomas W. Geisbert;Lisa E. Hensley;Tom Larsen;Howard A. Young

  • Interaction of NF-κB and NFAT with the Interferon-γ Promoter

    Antonio Sica;Linda Dorman;Vincenzo Viggiano;Marco Cippitelli

  • Role of interferon-gamma in immune cell regulation

    Howard A. Young;Kenneth J. Hardy

  • Interleukin 2 plays a central role in Th2 differentiation.

    Javier Cote-Sierra;Gilles Foucras;Liying Guo;Lynda Chiodetti

  • Interleukin-10 and the immune response against cancer: a counterpoint.

    Simone Mocellin;Francesco M. Marincola;Howard A. Young

  • Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys.

    Thomas W Geisbert;Lisa E Hensley;Peter B Jahrling;Tom Larsen

  • IL-18 is a potent coinducer of IL-13 in NK and T cells: a new potential role for IL-18 in modulating the immune response.

    Tomoaki Hoshino;Robert H. Wiltrout;Howard A. Young

  • Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.

    Ashley V. Menk;Nicole E. Scharping;Rebecca S. Moreci;Xue Zeng

  • Mechanisms Underlying Coagulation Abnormalities in Ebola Hemorrhagic Fever: Overexpression of Tissue Factor in Primate Monocytes/Macrophages Is a Key Event

    Thomas W. Geisbert;Howard A. Young;Peter B. Jahrling;Kelly J. Davis

  • Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus.

    R W Ellis;D DeFeo;J M Maryak;H A Young

  • Intracellular localization of human monocyte associated interleukin 1 (IL 1) activity and release of biologically active IL 1 from monocytes by trypsin and plasmin.

    Koji Matsushima;M. Taguchi;E. J. Kovacs;H. A. Young

  • Pathogenesis of Ebola Hemorrhagic Fever in Primate Models: Evidence that Hemorrhage Is Not a Direct Effect of Virus-Induced Cytolysis of Endothelial Cells

    Thomas W. Geisbert;Howard A. Young;Peter B. Jahrling;Kelly J. Davis

  • Bacillus anthracis lethal toxin induces TNF-α–independent hypoxia-mediated toxicity in mice

    Mahtab Moayeri;Diana Haines;Howard A. Young;Stephen H. Leppla

  • Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization.

    Alessandra Mazzoni;Howard A. Young;Jessica H. Spitzer;Alberto Visintin

Frequent Co-Authors

John R. Ortaldo
John R. Ortaldo National Institutes of Health
Robert H. Wiltrout
Robert H. Wiltrout National Institutes of Health
Edward M. Scolnick
Edward M. Scolnick Broad Institute
Jay H. Bream
Jay H. Bream Johns Hopkins University
Jianping Ye
Jianping Ye Shanghai Jiao Tong University
Thomas W. Geisbert
Thomas W. Geisbert The University of Texas Medical Branch at Galveston
Dan L. Longo
Dan L. Longo Harvard University
Scott K. Durum
Scott K. Durum National Institutes of Health
Stephan R. Targan
Stephan R. Targan Cedars-Sinai Medical Center
Stephen K. Anderson
Stephen K. Anderson National Institutes of Health

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Related Online Degrees & Career Pathways

For those interested in studying Immunology in the USA, exploring related healthcare degrees can open diverse career pathways. Many professionals leverage their background in immunology to transition into advanced nursing roles such as Nurse Practitioners (NPs). Programs like accelerated RN to NP programs cater to registered nurses aiming to enhance their credentials efficiently.

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Finally, understanding financial outcomes such as the DNP salary transparency across different states can inform decisions about education investments and career planning. By considering these related degrees and career pathways, immunology students can better align their academic pursuits with evolving healthcare opportunities.

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