World's Best Scientists 2026 revealed!

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Immunology

D-Index
79
Citations
23771
World Ranking
1677
National Ranking
826

Medicine

D-Index
80
Citations
24273
World Ranking
17081
National Ranking
8560

Research.com Recognitions

  • 2020 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Larry W. Kwak is affiliated with the City Of Hope National Medical Center in the United States. Their primary research focus is within the field of Medicine, with significant contributions across subfields such as Oncology, Pathology and Forensic Medicine, Immunology, Molecular Biology, and Genetics.

The scientist's work includes extensive research on CAR-T cell therapy, lymphoma diagnosis and treatment, and chronic lymphocytic leukemia. Additional research topics covered include monoclonal and polyclonal antibodies, immunotherapy and immune responses, immune cell function and interaction, and cancer immunotherapy and biomarkers.

Frequent publication venues for their work are as follows:

  • Blood
  • Blood Advances
  • The Lancet Haematology
  • Molecular Therapy
  • Clinical Lymphoma Myeloma & Leukemia

Notable recent papers authored or coauthored include:

  • Response-adapted anti-PD-1-based salvage therapy for Hodgkin lymphoma with nivolumab alone or in combination with ICE, 2022, Blood
  • The Cerebroventricular Environment Modifies CAR T Cells for Potent Activity against Both Central Nervous System and Systemic Lymphoma, 2020, Cancer Immunology Research
  • Double-hit Signature with TP53 Abnormalities Predicts Poor Survival in Patients with Germinal Center Type Diffuse Large B-cell Lymphoma Treated with R-CHOP, 2021, Clinical Cancer Research
  • Pembrolizumab plus vorinostat induces responses in patients with Hodgkin lymphoma refractory to prior PD-1 blockade, 2023, Blood
  • CD19/BAFF-R dual-targeted CAR T cells for the treatment of mixed antigen-negative variants of acute lymphoblastic leukemia, 2022, Leukemia

Collaborators who frequently coauthor with Larry W. Kwak include:

  • Stephen J. Forman
  • Alex F. Herrera
  • Steven T. Rosen
  • Leslie Popplewell
  • Matthew Mei

In 2020, Larry W. Kwak was recognized as a Fellow of the Indian National Academy of Engineering (INAE).

Best Publications

  • Toll-Like Receptor 4-Dependent Activation of Dendritic Cells by β-Defensin 2

    Arya Biragyn;Pier Adelchi Ruffini;Cynthia A. Leifer;Elena Klyushnenkova

  • Mammalian defensins in immunity: more than just microbicidal.

    De Yang;Arya Biragyn;Larry W Kwak;Joost J Oppenheim

  • Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma.

    Maurizio Bendandi;Christopher D. Gocke;Carol B. Kobrin;Floyd A. Benko

  • Induction of Immune Responses in Patients with B-Cell Lymphoma against the Surface-Immunoglobulin Idiotype Expressed by Their Tumors

    Larry W. Kwak;Michael J. Campbell;Debra K. Czerwinski;Sarah Hart

  • Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial

    Jason R Westin;Fuliang Chu;Min Zhang;Luis E Fayad

  • Tumor-Specific Idiotype Vaccines in the Treatment of Patients With B-Cell Lymphoma — Long-Term Results of a Clinical Trial

    Frank J. Hsu;Clemens B. Caspar;Debra Czerwinski;Larry W. Kwak

  • Roles of antimicrobial peptides such as defensins in innate and adaptive immunity

    J J Oppenheim;A Biragyn;L W Kwak;D Yang

  • Prognostic significance of actual dose intensity in diffuse large-cell lymphoma: results of a tree-structured survival analysis.

    L W Kwak;J Halpern;R A Olshen;S J Horning

  • Detection of Tumor Messenger RNA in the Serum of Patients with Malignant Melanoma

    Michael S. Kopreski;Floyd A. Benko;Larry W. Kwak;Christopher D. Gocke

  • Double hit lymphoma: the MD Anderson Cancer Center clinical experience.

    Yasuhiro Oki;Mansoor Noorani;Pei Lin;Richard E. Davis

  • Eight-year experience with allogeneic stem cell transplantation for relapsed follicular lymphoma after nonmyeloablative conditioning with fludarabine, cyclophosphamide, and rituximab.

    Issa F Khouri;Peter McLaughlin;Rima M Saliba;Chitra Hosing

  • Mediators of Innate Immunity That Target Immature, But Not Mature, Dendritic Cells Induce Antitumor Immunity When Genetically Fused with Nonimmunogenic Tumor Antigens

    Arya Biragyn;Munhsuren Surenhu;De Yang;Pier Adelchi Ruffini

  • Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity

    Arya Biragyn;Kenji Tani;Michael C. Grimm;Steven Weeks

  • Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial

    Michael Wang;Luis Fayad;Nicolaus A Wagner-Bartak;Liang Zhang

  • Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response.

    Larry W. Kwak;Howard A. Young;Robin W. Pennington;Steve D. Weeks

  • Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function

    Young Hee Lee;Natalia Martin-Orozco;Natalia Martin-Orozco;Peilin Zheng;Jing Li

  • Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor.

    L.W. Kwak;P.L. Duffey;C.W. Reynolds;D.L. Longo

  • Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004.

    Yuhong Zhou;Yuhong Zhou;Haijun Wang;Wenjing Fang;Jorge E. Romaguer

  • Ten-year follow-up after intense chemoimmunotherapy with Rituximab-HyperCVAD alternating with Rituximab-high dose methotrexate/cytarabine (R-MA) and without stem cell transplantation in patients with untreated aggressive mantle cell lymphoma

    Jorge E. Romaguera;Luis E. Fayad;Lei Feng;Kimberly Hartig

  • Safety and activity of lenalidomide and rituximab in untreated indolent lymphoma: an open-label, phase 2 trial

    Nathan H Fowler;R Eric Davis;Seema Rawal;Loretta Nastoupil

Frequent Co-Authors

Luis Fayad
Luis Fayad The University of Texas MD Anderson Cancer Center
Fredrick B. Hagemeister
Fredrick B. Hagemeister The University of Texas MD Anderson Cancer Center
Peter McLaughlin
Peter McLaughlin The University of Texas MD Anderson Cancer Center
Anas Younes
Anas Younes AstraZeneca (United Kingdom)
Qing Yi
Qing Yi Houston Methodist
Stephen J. Forman
Stephen J. Forman City Of Hope National Medical Center
Robert Z. Orlowski
Robert Z. Orlowski The University of Texas MD Anderson Cancer Center
Steven T. Rosen
Steven T. Rosen City Of Hope National Medical Center
Arya Biragyn
Arya Biragyn National Institutes of Health
Jatin P. Shah
Jatin P. Shah Memorial Sloan Kettering Cancer Center

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