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Medicine

D-Index
136
Citations
56481
World Ranking
2001
National Ranking
207

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

John G. Gribben is affiliated with Queen Mary University of London in the United Kingdom. Their research primarily spans medicine with a focus on hematology, oncology, molecular biology, genetics, and pathology. The scholar has contributed extensively to lymphoma diagnosis and treatment, chronic lymphocytic leukemia research, acute myeloid leukemia research, and CAR-T cell therapy research. Additional research topics include hematopoietic stem cell transplantation, immune cell function and interaction, and viral-associated cancers and disorders.

Frequent publication venues for their work include:

  • Blood
  • HemaSphere
  • bioRxiv (Cold Spring Harbor Laboratory)
  • British Journal of Haematology
  • Haematologica

Among their recent papers are:

  • The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee (2022, Blood)
  • Bone marrow niches in haematological malignancies (2020, Nature reviews. Cancer)
  • Management of adults and children receiving CAR T-cell therapy: 2021 best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA) (2021, Annals of Oncology)
  • Immune effector cell-associated hematotoxicity: EHA/EBMT consensus grading and best practice recommendations (2023, Blood)
  • Genomic profiling for clinical decision making in lymphoid neoplasms (2022, Blood)

Their frequent co-authors include:

  • Pedro R. Cutillas
  • Dominique Bonnet
  • Andrew Clear
  • Jude Fitzgibbon
  • Paola Ghione

John G. Gribben's main fields of study are Medicine and Biochemistry, Genetics and Molecular Biology, with key subfields including Molecular Biology, Hematology, Oncology, Pathology and Forensic Medicine, and Genetics.

They have been recognized as a Fellow of The Academy of Medical Sciences in the United Kingdom.

Best Publications

  • Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation

    Gordon J. Freeman;John G. Gribben;Vassiliki A. Boussiotis;Judy W. Ng

  • ZAP-70 Compared with Immunoglobulin Heavy-Chain Gene Mutation Status as a Predictor of Disease Progression in Chronic Lymphocytic Leukemia

    Laura Z. Rassenti;Lang Huynh;Tracy L. Toy;Liguang Chen

  • Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.

    Anupama Reddy;Jenny Zhang;Nicholas S. Davis;Andrea B. Moffitt

  • Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma.

    J G Gribben;A S Freedman;D Neuberg;D C Roy

  • Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation.

    Claude D. Gimmi;Gordon J. Freeman;John G. Gribben;Gary Gray

  • Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

    Jessica Okosun;Csaba Bödör;Jun Wang;Shamzah Araf

  • Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug

    Alan G. Ramsay;Amy J. Johnson;Abigail M. Lee;Güllü Gorgün

  • Chronic lymphocytic leukaemia.

    Thomas J. Kipps;Freda K. Stevenson;Catherine J. Wu;Carlo M. Croce

  • B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

    Claude D. Gimmi;Gordon J. Freeman;John G. Gribben;Kanji Sugita

  • Ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab in first-line treatment of chronic lymphocytic leukaemia (iLLUMINATE): a multicentre, randomised, open-label, phase 3 trial

    Carol Moreno;Richard Greil;Fatih Demirkan;Alessandra Tedeschi

  • Transplantation of anergic histoincompatible bone marrow allografts.

    Eva C. Guinan;Vassiliki A. Boussiotis;Donna Neuberg;Lisa LaVita Brennan

  • T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production.

    John C. Riches;Jeffrey K. Davies;Fabienne McClanahan;Rewas Fatah

  • Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.

    Gordon J. Freeman;Gary S. Gray;Claude D. Gimmi;David B. Lombard

  • Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma

    Abasi Ene–Obong;Andrew J. Clear;Jennifer Watt;Jennifer Watt;Jun Wang

  • Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production.

    G J Freeman;F Borriello;R J Hodes;H Reiser

  • Rituximab and CHOP Induction Therapy for Newly Diagnosed Mantle-Cell Lymphoma: Molecular Complete Responses Are Not Predictive of Progression-Free Survival

    Orion M. Howard;John G. Gribben;Donna S. Neuberg;Michael Grossbard

  • All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment.

    John G. Gribben;Arnold S. Freedman;Sunhee D. Woo;Kelly Blake

  • Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity

    Eva C. Guinan;John G. Gribben;Vicki A. Boussiotis;Gordon J. Freeman

  • Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma.

    JG Gribben;D Neuberg;AS Freedman;CD Gimmi

  • Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34- fraction

    David C. Taussig;Jacques Vargaftig;Farideh Miraki-Moud;Emmanuel Griessinger

Frequent Co-Authors

Lee M. Nadler
Lee M. Nadler Harvard University
Donna Neuberg
Donna Neuberg Harvard University
Arnold S. Freedman
Arnold S. Freedman Harvard University
Jude Fitzgibbon
Jude Fitzgibbon Queen Mary University of London
Thomas J. Kipps
Thomas J. Kipps University of California, San Diego
Gordon J. Freeman
Gordon J. Freeman Harvard University
Robert J. Soiffer
Robert J. Soiffer Harvard University
Jerome Ritz
Jerome Ritz Harvard University
Laura Z. Rassenti
Laura Z. Rassenti University of California, San Diego
Jennifer R. Brown
Jennifer R. Brown Harvard University

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