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Medicine

D-Index
87
Citations
43665
World Ranking
13407
National Ranking
6819

Overview

Laura Z. Rassenti is affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Genetics and Molecular Biology subfields. Their work also engages with Oncology, Immunology, and Pathology and Forensic Medicine.

The main topics covered in Laura Z. Rassenti's research include:

  • Chronic Lymphocytic Leukemia Research
  • Cancer Genomics and Diagnostics
  • Glycosylation and Glycoproteins Research
  • Immunodeficiency and Autoimmune Disorders
  • Lymphoma Diagnosis and Treatment
  • Cancer-related Molecular Pathways
  • Single-cell and spatial transcriptomics

Their recent published papers reflect these interests and include the following:

  • Molecular map of chronic lymphocytic leukemia and its impact on outcome, 2022, published in Nature Genetics
  • cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies, 2022, published in Nature Communications
  • Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment, 2021, published in Nature Cancer
  • Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome, 2023, published in Nature Medicine
  • Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History, 2021, published in Cancer Discovery

Laura Z. Rassenti frequently collaborates with several researchers, notably including:

  • Thomas J. Kipps
  • Donna Neuberg
  • Catherine J. Wu
  • Jennifer R. Brown
  • Gad Getz

Their work appears regularly in specific scientific journals and venues, with multiple publications in:

  • Blood
  • Cancer Research
  • Leukemia
  • Blood Cancer Discovery
  • Breast Cancer Research

Best Publications

  • Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

    George Adrian Calin;Calin Dan Dumitru;Masayoshi Shimizu;Roberta Bichi

  • miR-15 and miR-16 induce apoptosis by targeting BCL2.

    Amelia Cimmino;George Adrian Calin;Muller Fabbri;Marilena V. Iorio

  • A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia

    George Adrian Calin;Manuela Ferracin;Manuela Ferracin;Amelia Cimmino;Gianpiero Di Leva

  • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

    George Adrian Calin;Chang Gong Liu;Cinzia Sevignani;Manuela Ferracin

  • Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia.

    Andreas Rosenwald;Ash A. Alizadeh;George Widhopf;Richard Simon

  • ZAP-70 Compared with Immunoglobulin Heavy-Chain Gene Mutation Status as a Predictor of Disease Progression in Chronic Lymphocytic Leukemia

    Laura Z. Rassenti;Lang Huynh;Tracy L. Toy;Liguang Chen

  • Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

    Franco Fais;Fabio Ghiotto;Shiori Hashimoto;Brian Sellars

  • MiR-15a and miR-16-1 cluster functions in human leukemia.

    George A. Calin;Amelia Cimmino;Muller Fabbri;Manuela Ferracin

  • Ultraconserved Regions Encoding ncRNAs Are Altered in Human Leukemias and Carcinomas

    George A. Calin;Chang gong Liu;Manuela Ferracin;Terry Hyslop

  • Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group

    Torsten Haferlach;Alexander Kohlmann;Lothar Wieczorek;Giuseppe Basso

  • Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia.

    Liguang Chen;George Widhopf;George Widhopf;George Widhopf;Lang Huynh;Lang Huynh;Lang Huynh;Laura Rassenti;Laura Rassenti;Laura Rassenti

  • CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia

    William G. Wierda;Mark J. Cantwell;Sandra J. Woods;Laura Z. Rassenti

  • International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia

    A C Rawstron;N Villamor;M Ritgen;S Böttcher

  • Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

    Laura Z. Rassenti;Sonia Jain;Michael J. Keating;William G. Wierda

  • Reprogramming of miRNA networks in cancer and leukemia

    Stefano Volinia;Marco Galasso;Stefan Costinean;Luca Tagliavini

  • Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

    Tetsuya Fukuda;Liguang Chen;Tomoyuki Endo;Li Tang

  • Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins.

    George F. Widhopf;Laura Z. Rassenti;Traci L. Toy;John G. Gribben

  • Association of a microRNA/TP53 Feedback Circuitry With Pathogenesis and Outcome of B-cell Chronic Lymphocytic Leukemia

    Muller Fabbri;Arianna Bottoni;Masayoshi Shimizu;Riccardo Spizzo

  • ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia.

    Liguang Chen;John Apgar;Lang Huynh;Frank Dicker

  • Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy.

    Jennifer A. Woyach;Kelly Smucker;Lisa L. Smith;Arletta Lozanski

Frequent Co-Authors

Thomas J. Kipps
Thomas J. Kipps University of California, San Diego
Donna Neuberg
Donna Neuberg Harvard University
Jennifer R. Brown
Jennifer R. Brown Harvard University
Carlo M. Croce
Carlo M. Croce The Ohio State University
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute
Neil E. Kay
Neil E. Kay Mayo Clinic
Kanti R. Rai
Kanti R. Rai Hofstra University
William G. Wierda
William G. Wierda The University of Texas MD Anderson Cancer Center
John G. Gribben
John G. Gribben Queen Mary University of London
Michael J. Keating
Michael J. Keating The University of Texas MD Anderson Cancer Center

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