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Immunology

D-Index
56
Citations
18511
World Ranking
3669
National Ranking
320

Overview

De Yang is a researcher affiliated with the National Cancer Research Institute, UK. Their work spans multiple scientific fields with a focus on immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. Within these fields, their primary subfields of study include immunology, oncology, molecular biology, plant science, and neurology.

Their research topics mainly cover areas related to immunotherapy and immune responses, cancer immunotherapy and biomarkers, immune cell function and interaction, T-cell and B-cell immunology, RNA interference and gene delivery, cancer research and treatments, as well as Parkinson's disease mechanisms and treatments.

De Yang has contributed significantly to scientific literature, with recent publications including:

  • Interleukin-8: An evolving chemokine, 2022, Cytokine
  • Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function, 2022, Cell Reports
  • A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer, 2021, International Immunopharmacology
  • Reactive Oxygen Species-Sensitive Biodegradable Mesoporous Silica Nanoparticles Harboring TheraVac Elicit Tumor-Specific Immunity for Colon Tumor Treatment, 2023, ACS Nano
  • Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8+ T Cells, 2021, Cancer Immunology Research

Their frequent collaborators include researchers such as Joost J. Oppenheim, Md Masud Alam, Xiaoqing Li, Xin Chen, and Anna Trivett.

Among the publication venues where De Yang has frequently published are The Journal of Immunology, Cytokine, Frontiers in Immunology, Research Square, and Cell Reports.

Best Publications

  • Ll-37, the Neutrophil Granule–And Epithelial Cell–Derived Cathelicidin, Utilizes Formyl Peptide Receptor–Like 1 (Fprl1) as a Receptor to Chemoattract Human Peripheral Blood Neutrophils, Monocytes, and T Cells

    De Yang;Qian Chen;Albert P. Schmidt;G. Mark Anderson

  • Alarmins: chemotactic activators of immune responses.

    Joost J Oppenheim;De Yang

  • Mammalian defensins in immunity: more than just microbicidal.

    De Yang;Arya Biragyn;Larry W Kwak;Joost J Oppenheim

  • Multiple Roles of Antimicrobial Defensins, Cathelicidins, and Eosinophil-Derived Neurotoxin in Host Defense*

    De Yang;Arya Biragyn;David M. Hoover;Jacek Lubkowski

  • Human β-defensins

    M. Pazgier;D. M. Hoover;D. Yang;W. Lu

  • Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells.

    De Yang;Qian Chen;Oleg Chertov;Joost J. Oppenheim

  • Many chemokines including CCL20/MIP-3α display antimicrobial activity

    De Yang;Qian Chen;David M. Hoover;Patricia Staley

  • Roles of antimicrobial peptides such as defensins in innate and adaptive immunity

    J J Oppenheim;A Biragyn;L W Kwak;D Yang

  • Interleukin-8: An evolving chemokine.

    Unknown

  • Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3

    Zhibin Wu;David M. Hoover;De Yang;Cyril Boulègue

  • High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin.

    De Yang;Qian Chen;Huan Yang;Kevin J. Tracey

  • Alarmins and immunity

    De Yang;Zhen Han;Joost J. Oppenheim

  • Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

    De-Xuan Yang;Qian-Qian Chen;Shao Bo Su;Ping Zhang

  • Mediators of Innate Immunity That Target Immature, But Not Mature, Dendritic Cells Induce Antitumor Immunity When Genetically Fused with Nonimmunogenic Tumor Antigens

    Arya Biragyn;Munhsuren Surenhu;De Yang;Pier Adelchi Ruffini

  • Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2.

    Johann Röhrl;De Yang;Joost J. Oppenheim;Thomas Hehlgans

  • Participation of mammalian defensins and cathelicidins in anti-microbial immunity: receptors and activities of human defensins and cathelicidin (LL-37).

    De Yang;Oleg Chertov;Joost J. Oppenheim

  • Histidyl–tRNA Synthetase and Asparaginyl–tRNA Synthetase, Autoantigens in Myositis, Activate Chemokine Receptors on T Lymphocytes and Immature Dendritic Cells

    O.M. Zack Howard;Hui Fang Dong;De Yang;Nina Raben

  • The role of mammalian antimicrobial peptides and proteins in awakening of innate host defenses and adaptive immunity.

    D Yang;O Chertov;J J Oppenheim

  • The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins

    David M. Hoover;Cyril Boulègue;De Yang;Joost J. Oppenheim

  • Bacterial c-di-GMP Is an Immunostimulatory Molecule

    David K R Karaolis;Terry K Means;De Yang;Munehisa Takahashi

  • Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant

    Kahori Kurosaka;Qian Chen;Felix Yarovinsky;Joost J. Oppenheim

Frequent Co-Authors

Joost J. Oppenheim
Joost J. Oppenheim National Institutes of Health
Xin Chen
Xin Chen University of Macau
Michael Bustin
Michael Bustin National Institutes of Health
Arya Biragyn
Arya Biragyn National Institutes of Health
Ji Ming Wang
Ji Ming Wang National Institutes of Health
O. M. Zack Howard
O. M. Zack Howard National Institutes of Health
Wuyuan Lu
Wuyuan Lu University of Maryland, Baltimore
Zhigang Tian
Zhigang Tian University of Science and Technology of China
Larry W. Kwak
Larry W. Kwak City Of Hope National Medical Center
Helene F. Rosenberg
Helene F. Rosenberg National Institute of Allergy and Infectious Diseases

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