His primary areas of study are Microbiology, C5a peptidase, Group A, Virology and Molecular biology. His Microbiology study combines topics from a wide range of disciplines, such as Fibronectin, Internalization, Antibody, Mucous membrane of nose and Virulence. He focuses mostly in the field of C5a peptidase, narrowing it down to matters related to Bacterial adhesin and, in some cases, Spleen, Cellular immunity, In vitro, Mutation and Streptococcus agalactiae.
He combines subjects such as Penicillin, Immunology and Streptococcus with his study of Group A. His study on Virology also encompasses disciplines like
P. Patrick Cleary mostly deals with Microbiology, Molecular biology, Group A, Genetics and C5a peptidase. P. Patrick Cleary interconnects Antibody, Immunology, Antigen, Streptococcus and Virulence in the investigation of issues within Microbiology. His Immunology research focuses on Pharyngitis and how it relates to Sepsis and Rheumatic fever.
His study in Molecular biology is interdisciplinary in nature, drawing from both Binding protein, Recombinant DNA, Biochemistry, Peptide sequence and Myeloma protein. His work in Group A addresses subjects such as Virology, which are connected to disciplines such as Immunization. The concepts of his C5a peptidase study are interwoven with issues in Bacterial adhesin and Fibronectin.
P. Patrick Cleary spends much of his time researching Immunology, Microbiology, Immune system, Antigen and Group A. In his study, which falls under the umbrella issue of Immunology, In vivo, Endogeny, CD11c, Cell growth and Cytokine is strongly linked to Cellular differentiation. His research integrates issues of Bacterial adhesin, Virulence and Pharyngitis in his study of Microbiology.
His Immune system research includes themes of Proinflammatory cytokine and Rheumatic fever. His study in Antigen is interdisciplinary in nature, drawing from both Antibody and IL-2 receptor. His Group A research is multidisciplinary, incorporating elements of Computational biology and Reverse vaccinology.
P. Patrick Cleary focuses on Immunology, Interleukin 17, Microbiology, Immune system and Antigen. The various areas that he examines in his Interleukin 17 study include Lymphatic system and Interferon gamma. His research integrates issues of Adoptive cell transfer and Flow cytometry in his study of Lymphatic system.
His Microbiology research incorporates themes from Viral neuraminidase, Cell adhesion molecule, Coinfection, Bacterial adhesin and Transforming growth factor beta. P. Patrick Cleary has included themes like Pathogen, Cellular differentiation, Cytokine, Group A streptococcal infection and Virulence in his Immune system study. His work in Antigen covers topics such as Cytotoxic T cell which are related to areas like Virology.
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Clonal basis for resurgence of serious Streptococcus pyogenes disease in the 1980s.
P. P. Cleary;P. M. Schlievert;J. P. Handley;Michael H Kim.
The Lancet (1992)
Group A streptococci efficiently invade human respiratory epithelial cells
Diqui Lapenta;Craig Rubens;Emil Chi;P. Patrick Cleary.
Proceedings of the National Academy of Sciences of the United States of America (1994)
C5a peptidase alters clearance and trafficking of group A streptococci by infected mice.
Yinduo Ji;Lynne Mclandsborough;Aparna Kondagunta;Patrick Cleary.
Infection and Immunity (1996)
Different routes of bacterial infection induce long-lived T H 1 memory cells and short-lived T H 17 cells
Marion Pepper;Jonathan L Linehan;Antonio J Pagán;Traci Zell.
Nature Immunology (2010)
Streptococcus pyogenes Serotype M1 Encodes Multiple Pathways for Entry into Human Epithelial Cells
D. Cue;P. E. Dombek;H. Lam;P. P. Cleary.
Infection and Immunity (1998)
Mechanism of action of the group A streptococcal C5a inactivator
Daniel E. Wexler;Dennis E. Chenoweth;P. Patrick Cleary.
Proceedings of the National Academy of Sciences of the United States of America (1985)
Streptococcal C5a peptidase is a highly specific endopeptidase.
P P Cleary;U Prahbu;J B Dale;D E Wexler.
Infection and Immunity (1992)
Intranasal immunization with C5a peptidase prevents nasopharyngeal colonization of mice by the group A Streptococcus
Yinduo Ji;Brian Carlson;Aparna Kondagunta;P. Patrick Cleary.
Infection and Immunity (1997)
Fc-receptor and M-protein genes of group A streptococci are products of gene duplication
David G. Heath;P. Patrick Cleary.
Proceedings of the National Academy of Sciences of the United States of America (1989)
Membranous Cells in Nasal-Associated Lymphoid Tissue: A Portal of Entry for the Respiratory Mucosal Pathogen Group A Streptococcus
Hae Sun Park;Kevin P. Francis;Jun Yu;P. Patrick Cleary.
Journal of Immunology (2003)
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