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D-Index & Metrics

Genetics

D-Index
49
Citations
11498
World Ranking
3982
National Ranking
459

Overview

Julia R. Dorin is affiliated with the University of Edinburgh in the United Kingdom. Their research spans several areas within immunology, microbiology, and biochemistry, with a focus on antimicrobial peptides and immune response mechanisms.

Their recent publications include:

  • The Dichotomous Responses Driven by β-Defensins (2020, Frontiers in Immunology)
  • A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro (2023, Scientific Reports)
  • Classical macrophage polarisation is limited by human β-defensin-3 via an autocrine IL-4 dependent process (2021, bioRxiv (Cold Spring Harbor Laboratory))
  • SAAP-148 and halicin exhibit synergistic antimicrobial activity against antimicrobial-resistant bacteria in skin but not airway epithelial culture models (2025, JAC-Antimicrobial Resistance)

Frequent coauthors working alongside Julia R. Dorin include:

  • Donald J. Davidson
  • Jennifer Shelley
  • Brian J. McHugh
  • Jimi Wills
  • Richard Weller

They have published in the following venues multiple times:

  • Frontiers in Immunology
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • JAC-Antimicrobial Resistance

Their work covers main fields of study such as:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these areas, subfields of research include:

  • Microbiology
  • Immunology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Dermatology

The primary research topics addressed in their publications are:

  • Antimicrobial Peptides and Activities
  • Immune Response and Inflammation
  • Neuropeptides and Animal Physiology
  • Dermatology and Skin Diseases
  • Allergic Rhinitis and Sensitization
  • Chemokine receptors and signaling
  • Animal Genetics and Reproduction

Best Publications

  • Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.

    Natasha J. Caplen;Eric W.F.W. Alton;Peter G. Mddleton;Julia R. Dorin

  • The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis

    Matteo Ruggiu;Robert Speed;Mary Taggart;Stewart J. McKay

  • The VPAC2 Receptor Is Essential for Circadian Function in the Mouse Suprachiasmatic Nuclei

    Anthony J. Harmar;Hugh M. Marston;Sanbing Shen;Christopher Spratt

  • The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

    Niamh M. Mannion;Sam M. Greenwood;Robert Young;Sarah Cox

  • Enzymatic removal of ribonucleotides from DNA is essential for Mammalian genome integrity and development

    Martin A.M. Reijns;Björn Rabe;Rachel E. Rigby;Pleasantine Mill

  • Evidence for stem-cell niches in the tracheal epithelium.

    D W Borthwick;M Shahbazian;Q T Krantz;J R Dorin

  • Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis.

    David Porteous;J R Dorin;Gerry McLachlan;H Davidson-Smith

  • β-Defensins: multifunctional modulators of infection, inflammation and more?

    Fiona Semple;Julia R Dorin

  • Cystic fibrosis in the mouse by targeted insertional mutagenesis.

    Julia R. Dorin;Paul Dickinson;Eric W. F. W. Alton;Stephen N. Smith

  • A clue to the basic defect in cystic fibrosis from cloning the CF antigen gene

    Julia R. Dorin;Michal Novak;Robert E. Hill;David J. H. Brock

  • Expression pattern of two related cystic fibrosis-associated calcium-binding proteins in normal and abnormal tissues.

    M. M. Wilkinson;A. Busuttil;C. Hayward;D. J. H. Brock

  • Characterization of the mouse beta defensin 1, Defb1, mutant mouse model

    Gillian Morrison;Fiona Kilanowski;Donald Davidson;Julia Dorin

  • Duplication and selection in the evolution of primate β-defensin genes

    Colin A M Semple;Mark Rolfe;Julia R Dorin

  • Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo.

    Fiona Semple;Sheila Webb;Hsin-Ni Li;Hetal B. Patel

  • The mouse bagpipe gene controls development of axial skeleton, skull, and spleen.

    Laura A. Lettice;Lorna A. Purdie;Geoffrey J. Carlson;Fiona Kilanowski

  • Structure-activity relationships in beta-defensin peptides.

    Karen Taylor;Perdita E. Barran;Julia R. Dorin

  • Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens

    Donald J. Davidson;Julia R. Dorin;Gerard McLachlan;Vincent Ranaldi

  • A demonstration using mouse models that successful gene therapy for cystic fibrosis requires only partial gene correction

    J. R. Dorin;R. Farley;S. Webb;S. N. Smith

  • Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype-phenotype correlations.

    Stephen J. Delaney;Eric W.F.W. Alton;Stephen N. Smith;Dominic P. Lunn

  • Early alterations in airway mucociliary clearance and inflammation of the lamina propria in CF mice

    J. M. Zahm;D. Gaillard;F. Dupuit;J. Hinnrasky

Frequent Co-Authors

David J. Porteous
David J. Porteous University of Edinburgh
Donald J. Davidson
Donald J. Davidson University of Edinburgh
Perdita E. Barran
Perdita E. Barran University of Manchester
John R. W. Govan
John R. W. Govan University of Edinburgh
Robert E. Hill
Robert E. Hill University of Edinburgh
Duncan M. Geddes
Duncan M. Geddes Imperial College London
Colin A. Semple
Colin A. Semple University of Edinburgh
Veronica van Heyningen
Veronica van Heyningen University College London
Eric W.F.W. Alton
Eric W.F.W. Alton National Institutes of Health
Robert Williamson
Robert Williamson University of Melbourne

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