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Immunology

D-Index
90
Citations
28183
World Ranking
1078
National Ranking
581

Overview

John R. Ortaldo is affiliated with the National Institutes of Health in the United States. The body of work associated with this researcher primarily focuses on immunology and related fields, as evidenced by publication venues and collaborative efforts.

One of the recent contributions by this scientist is a paper titled Dr. Howard Young: A Unique NCI Investigator, published in 2022 in the Journal of Interferon & Cytokine Research. This paper reflects involvement in detailed biomedical research centered on cytokines and immune response mechanisms.

Collaborative research forms a part of their academic activity. A notable frequent co-author of this scientist is Robin Winkler Pickett, illustrating teamwork in the research process and shared scientific inquiries.

Publications by John R. Ortaldo have appeared in the following venues:

  • Journal of Interferon & Cytokine Research

The thematic scope of their work centers on immunological factors, with a significant focus on cytokine research and interferon studies, based on the journal selection for publication. The affiliation with a major research institution such as the National Institutes of Health underscores engagement with biomedical research at a national level.

Best Publications

  • Natural Killer Cells: Their Roles in Defenses Against Disease

    Unknown

  • Recombinant Human Interferon-inducible Protein 10 Is a Chemoattractant for Human Monocytes and T Lymphocytes and Promotes T Cell Adhesion to Endothelial Cells

    Dennis D. Taub;Andrew R. Lloyd;Kevin Conlon;Ji Ming Wang

  • Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2

    James A. Johnston;Masaru Kawamura;Robert A. Kirken;Yi Qing Chen

  • Augmentation by interferon of human natural and antibody-dependent cell-mediated cytotoxicity.

    Ronald R. Herberman;John R. Ortaldo;Guy D. Bonnard

  • Natural Killer Cells: Characteristics and Regulation of Activity

    Ronald B. Herberman;Ronald B. Herberman;Ronald B. Herberman;Julie Y. Djeu;Julie Y. Djeu;Julie Y. Djeu;H. David Kay;H. David Kay;H. David Kay;John R. Ortaldo;John R. Ortaldo;John R. Ortaldo

  • Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.

    Chris M. Bacon;Emanuel F. Petricoin;John R. Ortaldo;Robert C. Rees

  • Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis.

    D. D. Taub;T. J. Sayers;C. R. D. Carter;J. R. Ortaldo

  • Lymphokine-activated killer cells. Analysis of progenitors and effectors.

    J R Ortaldo;A Mason;R Overton

  • Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.

    J R Ortaldo;S O Sharrow;T Timonen;R B Herberman

  • HETEROGENEITY OF NATURAL KILLER CELLS

    John R. Ortaldo;Ronald B. Herberman

  • Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

    J A Johnston;C M Bacon;D S Finbloom;R C Rees

  • Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.

    Chris M. Bacon;Daniel W. McVicar;John R. Ortaldo;Robert C. Rees

  • Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

    M Kawamura;D W McVicar;J A Johnston;T B Blake

  • Effects of natural and recombinant IL 2 on regulation of IFN gamma production and natural killer activity: lack of involvement of the Tac antigen for these immunoregulatory effects.

    J R Ortaldo;A T Mason;J P Gerard;L E Henderson

  • Mechanism of cytotoxicity by natural killer (NK) cells.

    Ronald B. Herberman;Craig W. Reynolds;John R. Ortaldo

  • A new immunodeficiency disorder in humans involving NK cells.

    John C. Roder;John C. Roder;Tina Haliotis;Tina Haliotis;Margareta Klein;Margareta Klein;Stefan Korec

  • Role of organ-associated NK cells in decreased formation of experimental metastases in lung and liver.

    R. H. Wiltrout;R. B. Herberman;Shu-Ren Zhang;M. A. Chirigos

  • Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE.

    Xin Chen;Joost J Oppenheim;Robin T Winkler-Pickett;John R Ortaldo

  • Beta chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production

    Dennis D. Taub;John R. Ortaldo;Susan M. Turcovski-Corrales;Michael L. Key

  • DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase.

    Daniel W. McVicar;Lynn S. Taylor;Pierre Gosselin;Jami Willette-Brown

  • Human large granular lymphocytes are potent producers of interleukin-1

    Giuseppe Scala;Paola Allavena;Julie Y. Djeu;Tadashi Kasahara

Frequent Co-Authors

Ronald B. Herberman
Ronald B. Herberman University of Pittsburgh
Howard A. Young
Howard A. Young National Institutes of Health
Robert H. Wiltrout
Robert H. Wiltrout National Institutes of Health
Dan L. Longo
Dan L. Longo Harvard University
Daniel W. McVicar
Daniel W. McVicar National Institutes of Health
Stephen K. Anderson
Stephen K. Anderson National Institutes of Health
William J. Murphy
William J. Murphy Texas A&M University
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
John J. O'Shea
John J. O'Shea National Institutes of Health
Joost J. Oppenheim
Joost J. Oppenheim National Institutes of Health

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