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Immunology

D-Index
80
Citations
27033
World Ranking
1611
National Ranking
31

Research.com Recognitions

  • 2002 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Klas Kärre is affiliated with the Karolinska Institute in Sweden. Their research primarily focuses on Immunology and Microbiology as well as Medicine. Within these fields, their work concentrates on subfields including Immunology, Oncology, Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging, and Economics and Econometrics.

The main topics Klas Kärre explores include:

  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Immune cells in cancer
  • Ferroptosis and cancer prognosis

The scientist has contributed to several recent publications, notable examples include:

  • "Towards a cancer mission in Horizon Europe: recommendations," 2020, published in Molecular Oncology
  • "Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer," 2023, published in European Journal of Cancer
  • "Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade," 2021, published in Cancers
  • "Infiltration of NK and plasma cells is associated with a distinct immune subset in non-small cell lung cancer," 2021, published in The Journal of Pathology
  • "WITHDRAWN: Characterization of Patterns of Immune Cell Infiltration in NSCLC," 2020, published in Journal of Thoracic Oncology

Klas Kärre often collaborates with a consistent group of coauthors, including Johanna Sofia Margareta Mattsson, Johan Botling, Patrick Micke, Max Backman, and Artur Mezheyeuski. These collaborations have contributed to a number of publications.

Their research is regularly published in journals such as Journal of Thoracic Oncology, Cancers, bioRxiv (Cold Spring Harbor Laboratory), Regular and Young Investigator Award Abstracts, and Molecular Oncology, reflecting an established contribution across several venues.

Klas Kärre has been recognized with memberships in professional organizations including the Academia Europaea since 2002 and the European Molecular Biology Organization (EMBO).

Best Publications

  • In search of the 'missing self': MHC molecules and NK cell recognition.

    Hans-Gustaf Ljunggren;Klas Kärre

  • Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

    Klas Kärre;Hans Gustaf Ljunggren;Gerald Piontek;Rolf Kiessling

  • Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism.

    Hans-Gustaf Ljunggren;Klas Karre

  • Association of class I major histocompatibility heavy and light chains induced by viral peptides.

    Alain Townsend;Claes Öhlén;Judy Bastin;Hans-Gustaf Ljunggren

  • Empty MHC class I molecules come out in the cold

    H G Ljunggren;N J Stam;C Ohlén;J J Neefjes

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

    Tadepally Lakshmikanth;Shannon Burke;Talib Hassan Ali;Silvia Kimpfler

  • Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice

    Petter Hoglund;Claes Ohlen;Ennio Carbone;Lars Franksson

  • Natural killer cell recognition of missing self

    Klas Kärre

  • A Signal Peptide Derived from hsp60 Binds HLA-E and Interferes with CD94/NKG2A Recognition

    Jakob Michaëlsson;Cristina Teixeira de Matos;Adnane Achour;Lewis L. Lanier

  • NK cell education: not an on-off switch but a tunable rheostat

    Petter Brodin;Klas Kärre;Petter Höglund

  • A New Mechanism of NK Cell Cytotoxicity Activation: The CD40–CD40 Ligand Interaction

    Ennio Carbone;Giuseppina Ruggiero;Giuseppe Terrazzano;Carmen Palomba

  • The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells

    Petter Brodin;Tadepally Lakshmikanth;Sofia Johansson;Klas Kärre

  • NK Cells, MHC Class I Molecules and the Missing Self

    Unknown

  • A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy.

    Alexandre L. R. Oliveira;Sebastian Thams;Olle Lidman;Fredrik Piehl

  • Prevention of allogeneic bone marrow graft rejection by H-2 transgene in donor mice

    Claes Öhlén;Gunilla Kling;Petter Höglund;Mona Hansson

  • Human NK Cells Selective Targeting of Colon Cancer–Initiating Cells: A Role for Natural Cytotoxicity Receptors and MHC Class I Molecules

    Rossana Tallerico;Matilde Todaro;Simone Di Franco;Cristina MacCalli

  • Effects of Human Cytomegalovirus Infection on Ligands for the Activating NKG2D Receptor of NK Cells: Up-Regulation of UL16-Binding Protein (ULBP)1 and ULBP2 Is Counteracted by the Viral UL16 Protein

    Alexander Rölle;Mehrdad Mousavi-Jazi;Mikael Eriksson;Jenny Odeberg

  • Allorecognition by NK cells: nonself or no self?

    Lorenzo Moretta;Ermanno Ciccone;Alessandro Moretta;Petter Höglund

  • YAC-1 MHC class I variants reveal an association between decreased NK sensitivity and increased H-2 expression after interferon treatment or in vivo passage.

    G E Piontek;K Taniguchi;H G Ljunggren;A Grönberg

  • Killer cells: a functional comparison between natural, immune T-cell and antibody-dependent in vitro systems.

    Rolf Kiessling;Rolf Kiessling;Gyözö Petranyi;Klas Kärre;Klas Kärre;Mikael Jondal;Mikael Jondal

  • Host MHC class I gene control of NK-cell specificity in the mouse.

    Petter Hoglund;Jonas Sundback;Mats Y. Olsson-Alheim;Maria Johansson

  • Express yourself or die: Peptides, MHC molecules, and NK cells

    Klas Kärre

Frequent Co-Authors

Hans-Gustaf Ljunggren
Hans-Gustaf Ljunggren Karolinska Institute
Petter Höglund
Petter Höglund Karolinska Institute
Rolf Kiessling
Rolf Kiessling Karolinska Institute
George Klein
George Klein Karolinska Institute
Jakob Michaëlsson
Jakob Michaëlsson Karolinska University Hospital
Johan K. Sandberg
Johan K. Sandberg Karolinska University Hospital
Petter Brodin
Petter Brodin Karolinska Institute
Alain Townsend
Alain Townsend University of Oxford
Robert A. Harris
Robert A. Harris Karolinska Institute
Francesco Colucci
Francesco Colucci University of Cambridge

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