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Robert A. Harris

Robert A. Harris

D-Index & Metrics

Microbiology

D-Index
60
Citations
12652
World Ranking
3132
National Ranking
61

Overview

Robert A. Harris is affiliated with the Karolinska Institute in Sweden. Their research spans multiple disciplines including Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. The scientist has produced significant work in subfields such as Immunology, Neurology, Molecular Biology, Physiology, and Genetics.

The main topics addressed in their research include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immune cells in cancer
  • Alzheimer's disease research and treatments
  • Immune Response and Inflammation
  • Immunotherapy and Immune Responses
  • Amyotrophic Lateral Sclerosis Research
  • Adenosine and Purinergic Signaling

Robert A. Harris has collaborated extensively with several coauthors, including:

  • Jinming Han
  • Keying Zhu
  • Heela Sarlus
  • Harald Lund
  • Xing-Mei Zhang

Their publications are frequently found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroinflammation
  • Nature Medicine
  • Brain Behavior and Immunity
  • International Journal of Molecular Sciences

Recent papers authored or coauthored by Robert A. Harris include:

  • Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation, 2020, Science Immunology
  • Microglial replacement therapy: a potential therapeutic strategy for incurable CSF1R-related leukoencephalopathy, 2020, Acta Neuropathologica Communications
  • Uncovering sex differences of rodent microglia, 2021, Journal of Neuroinflammation
  • Altered perivascular fibroblast activity precedes ALS disease onset, 2021, Nature Medicine
  • Inhibition of colony stimulating factor-1 receptor (CSF-1R) as a potential therapeutic strategy for neurodegenerative diseases: opportunities and challenges, 2022, Cellular and Molecular Life Sciences

The work of Robert A. Harris is situated at the intersection of immunology and neurology, focusing on immune mechanisms underlying neurodegenerative diseases and neuroinflammatory processes. This includes investigation of microglial behavior, therapeutic strategies targeting the colony stimulating factor-1 receptor, and studying sex differences in microglial function.

Best Publications

  • Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

    Ingunn M Stromnes;Lauren M Cerretti;Denny Liggitt;Robert A Harris

  • RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages.

    R. Kokkola;Å. Andersson;G. Mullins;T. Östberg

  • Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

    Anna-Maria Georgoudaki;Kajsa E. Prokopec;Vanessa F. Boura;Eva Hellqvist

  • A Breakthrough: Macrophage-Directed Cancer Immunotherapy

    Charles D. Mills;Laurel L. Lenz;Robert A. Harris

  • CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

    Moa Fransson;Elena Piras;Joachim Burman;Berith Nilsson

  • Regulation of Pyruvate Dehydrogenase Kinase Expression by Peroxisome Proliferator–Activated Receptor-α Ligands, Glucocorticoids, and Insulin

    Boli Huang;Pengfei Wu;Melissa M. Bowker-Kinley;Robert A. Harris

  • An optimized protocol for human M2 macrophages using M-CSF and IL-4/IL-10/TGF-β yields a dominant immunosuppressive phenotype.

    S. Mia;A. Warnecke;X.‐M. Zhang;V. Malmström

  • Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes

    Carl-David Agardh;Corrado M. Cilio;ÅsaLinda Lethagen;Kristian Lynch

  • T Cell Ig- and Mucin-Domain-Containing Molecule-3 (TIM-3) and TIM-1 Molecules Are Differentially Expressed on Human Th1 and Th2 Cells and in Cerebrospinal Fluid-Derived Mononuclear Cells in Multiple Sclerosis

    Mohsen Khademi;Zsolt Illés;Alexander W. Gielen;Monica Marta

  • Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis

    Åsa Andersson;Ruxandra Covacu;Dan Sunnemark;Alexandre I. Danilov

  • Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

    Roham Parsa;Pernilla Andresen;Alan Gillett;Sohel Mia

  • Cytokine patterns in cancer patients: A review of the correlation between interleukin 6 and prognosis.

    Bodo E. Lippitz;Robert A. Harris

  • Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells.

    Harald Lund;Melanie Pieber;Roham Parsa;Jinming Han

  • Protein Kinase B-α Inhibits Human Pyruvate Dehydrogenase Kinase-4 Gene Induction by Dexamethasone Through Inactivation of FOXO Transcription Factors

    Hye Sook Kwon;Boli Huang;Terry G. Unterman;Robert A. Harris

  • Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice

    Nam Ho Jeoung;Robert A. Harris

  • Isolation of rabbit liver branched chain alpha-ketoacid dehydrogenase and regulation by phosphorylation.

    R. Paxton;Robert Harris

  • Uncovering sex differences of rodent microglia.

    Jinming Han;Yueshan Fan;Kai Zhou;Kai Zhou;Klas Blomgren;Klas Blomgren

  • Short-term Hormonal Control of Hepatic Lipogenesis

    Math J H Geelen;Robert A Harris;Anton C Beynen;Sylvia A McCune

  • Mechanism responsible for 5-(tetradecyloxy)-2-furoic acid inhibition of hepatic lipogenesis.

    S. A. McCune;Robert Harris

  • Inhibition of colony stimulating factor-1 receptor (CSF-1R) as a potential therapeutic strategy for neurodegenerative diseases: opportunities and challenges

    Unknown

  • Tumor-Specific Bacteriophages Induce Tumor Destruction through Activation of Tumor-Associated Macrophages

    Fredrik Eriksson;Panagiotis Tsagozis;Kajsa Lundberg;Roham Parsa

  • Novel Mechanism of Macrophage-Mediated Metastasis Revealed in a Zebrafish Model of Tumor Development

    Jian Wang;Ziquan Cao;Xing-Mei Zhang;Masaki Nakamura

Frequent Co-Authors

Tomas Olsson
Tomas Olsson Karolinska Institute
Klas Blomgren
Klas Blomgren Karolinska Institute
David W. Crabb
David W. Crabb Indiana University
Klas Kärre
Klas Kärre Karolinska Institute
Mohsen Khademi
Mohsen Khademi Karolinska Institute
Gunter Schneider
Gunter Schneider Karolinska Institute
Hans Lassmann
Hans Lassmann Medical University of Vienna
Yoshiharu Shimomura
Yoshiharu Shimomura Nagoya University
Fredrik Piehl
Fredrik Piehl Karolinska Institute
Jakob Michaëlsson
Jakob Michaëlsson Karolinska University Hospital

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