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89
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35320
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12533
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Overview

Fredrik Piehl is affiliated with the Karolinska Institute in Sweden and has contributed extensively to research in the field of medicine, with a primary focus on neurology. Their body of work covers a range of topics including multiple sclerosis research studies, peripheral neuropathies and disorders, amyotrophic lateral sclerosis research, polyomavirus and related diseases, tryptophan and brain disorders, myasthenia gravis and thymoma, as well as neuroinflammation and neurodegeneration mechanisms.

Among recent publications by Piehl are several influential papers such as:

  • Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study (2020, The Lancet Neurology)
  • Neurofilaments as biomarkers in neurological disorders - towards clinical application (2024, Nature Reviews Neurology)
  • Confounding effect of blood volume and body mass index on blood neurofilament light chain levels (2020, Annals of Clinical and Translational Neurology)
  • Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis (2023, JAMA Neurology)
  • Treatment Escalation vs Immediate Initiation of Highly Effective Treatment for Patients With Relapsing-Remitting Multiple Sclerosis (2021, JAMA Neurology)

Frequent coauthors collaborating with Piehl include:

  • Tomas Olsson
  • Ingrid Kockum
  • Tobias Granberg
  • Thomas Frisell
  • Jan Hillert

Piehl's research has been published primarily in several notable scientific venues, with multiple publications in each, such as:

  • Neurology (14 publications)
  • Multiple Sclerosis and Related Disorders (12 publications)
  • Annals of Neurology (11 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (11 publications)
  • Multiple Sclerosis Journal (9 publications)

Their work spans multiple subfields including neurology, pathology and forensic medicine, molecular biology, immunology, and oncology. The concentration in neurology is reflected in the number of publications, highlighting a focus on diseases and disorders related to the nervous system.

Best Publications

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Neurofilaments as biomarkers in neurological disorders

    Michael Khalil;Charlotte E. Teunissen;Markus Otto;Fredrik Piehl

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

    James F Howard;Kimiaki Utsugisawa;Michael Benatar;Hiroyuki Murai

  • Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis

    Bridel C;van Wieringen Wn;Zetterberg H;Tijms Bm

  • Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis.

    Ivan Jelcic;Faiez Al Nimer;Faiez Al Nimer;Jian Wang;Verena Lentsch

  • Infection Risks Among Patients With Multiple Sclerosis Treated With Fingolimod, Natalizumab, Rituximab, and Injectable Therapies.

    Gustavo Luna;Peter Alping;Joachim Burman;Katharina Fink

  • Risk factors for amyotrophic lateral sclerosis.

    Caroline Ingre;Per M Roos;Fredrik Piehl;Freya Kamel

  • Monitoring disease activity in multiple sclerosis using serum neurofilament light protein.

    Lenka Novakova;Henrik Zetterberg;Peter Sundström;Markus Axelsson

  • MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

    Maria Swanberg;Olle Lidman;Leonid Padyukov;Per Eriksson

  • Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study.

    Anna He;Bernd Merkel;James William L Brown;James William L Brown;James William L Brown;Lana Zhovits Ryerson

  • Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab.

    Martin Gunnarsson;Clas Malmeström;Markus Axelsson;Peter Sundström

  • Neuroprotection by Encephalomyelitis: Rescue of Mechanically Injured Neurons and Neurotrophin Production by CNS-Infiltrating T and Natural Killer Cells

    H. Hammarberg;O. Lidman;C. Lundberg;S. Y. Eltayeb

  • Rituximab in multiple sclerosis : a retrospective observational study on safety and efficacy

    Jonatan Salzer;Rasmus Svenningsson;Peter Alping;Lenka Novakova

  • Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

    J. Kuhle;G. Disanto;R. Dobson;R. Adiutori

  • A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy.

    Alexandre L. R. Oliveira;Sebastian Thams;Olle Lidman;Fredrik Piehl

  • Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

    Mohsen Khademi;Ingrid Kockum;Magnus L Andersson;Ellen Iacobaeus

  • Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

    Jeppe Romme Christensen;Lars Börnsen;Rikke Ratzer;Fredrik Piehl

  • T Cell Ig- and Mucin-Domain-Containing Molecule-3 (TIM-3) and TIM-1 Molecules Are Differentially Expressed on Human Th1 and Th2 Cells and in Cerebrospinal Fluid-Derived Mononuclear Cells in Multiple Sclerosis

    Mohsen Khademi;Zsolt Illés;Alexander W. Gielen;Monica Marta

  • Gdnf mrna in Schwann cells and Drg satellite cells after chronic sciatic nerve injury

    H. Hammarberg;F. Piehl;S. Cullheim;J. Fjell

Frequent Co-Authors

Tomas Olsson
Tomas Olsson Karolinska Institute
Mohsen Khademi
Mohsen Khademi Karolinska Institute
Ingrid Kockum
Ingrid Kockum Karolinska Institute
Jan Hillert
Jan Hillert Karolinska Institute
Staffan Cullheim
Staffan Cullheim Karolinska Institute
Kaj Blennow
Kaj Blennow University of Gothenburg
Scott Montgomery
Scott Montgomery Örebro University
Lars Alfredsson
Lars Alfredsson Karolinska Institute
Jesper Tegnér
Jesper Tegnér King Abdullah University of Science and Technology
Tommy Olsson
Tommy Olsson Umeå University

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