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Yoshiharu Shimomura

Yoshiharu Shimomura

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9636
World Ranking
15713
National Ranking
1120

Overview

Yoshiharu Shimomura is affiliated with Nagoya University in Japan and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, as well as medicine. Their research spans multiple subfields including molecular biology, physiology, cell biology, endocrinology, diabetes and metabolism, and genetics.

Their work addresses topics such as gut microbiota and health, diet and metabolism studies, adipose tissue and metabolism, muscle metabolism and nutrition, muscle physiology and disorders, and diet, metabolism, and disease. Their research interests also cover biochemical effects in animals.

Shimomura's recent publications reflect these focal areas. Notable papers include:

  • "Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity" (2021, iScience)
  • "Tolerable amounts of amino acids for human supplementation: summary and lessons from published peer-reviewed studies" (2021, Amino Acids)
  • "Branched-chain amino acid supplementation ameliorates angiotensin II-induced skeletal muscle atrophy" (2020, Life Sciences)
  • "Supplementation of 1-Kestose Modulates the Gut Microbiota Composition to Ameliorate Glucose Metabolism in Obesity-Prone Hosts" (2021, Nutrients)
  • "Efficacy of 1-kestose supplementation in patients with mild to moderate ulcerative colitis: A randomised, double-blind, placebo-controlled pilot study" (2023, Alimentary Pharmacology & Therapeutics)

Their frequent co-authors include Yasuyuki Kitaura, Yoshihiro Kadota, Ayako Watanabe, Takumi Tochio, and Akihito Endo. These collaborations have contributed to multiple papers and research projects in their main fields of study.

Shimomura has published mainly in journals like Nutrients, Scientific Reports, Bioscience Biotechnology and Biochemistry, Journal of Nutritional Science and Vitaminology, and iScience. These venues are consistent with their focus on nutritional science, metabolism, and molecular biology.

Best Publications

  • Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise

    Yoshiharu Shimomura;Taro Murakami;Naoya Nakai;Masaru Nagasaki

  • A molecular model of human branched-chain amino acid metabolism.

    A Suryawan;J W Hawes;R A Harris;Y Shimomura

  • Less body fat accumulation in rats fed a safflower oil diet than in rats fed a beef tallow diet.

    Yoshiharu Shimomura;Tomohiro Tamura;Masashige Suzuki

  • Nutraceutical Effects of Branched-Chain Amino Acids on Skeletal Muscle

    Yoshiharu Shimomura;Yuko Yamamoto;Gustavo Bajotto;Juichi Sato

  • Branched-chain alpha-ketoacid dehydrogenase kinase. Molecular cloning, expression, and sequence similarity with histidine protein kinases.

    Kirill M. Popov;Yu Zhao;Yoshiharu Shimomura;Martha J. Kuntz

  • Diet-Induced Thermogenesis Is Lower in Rats Fed a Lard Diet Than in Those Fed a High Oleic Acid Safflower Oil Diet, a Safflower Oil Diet or a Linseed Oil Diet

    Hiroyuki Takeuchi;Tatsuhiro Matsuo;Kumpei Tokuyama;Yoshiharu Shimomura

  • Primary structure of pyruvate dehydrogenase kinase establishes a new family of eukaryotic protein kinases

    Kirill M. Popov;Natalia Y. Kedishvili;Yu Zhao;Yoshiharu Shimomura

  • Lemon flavonoid, eriocitrin, suppresses exercise-induced oxidative damage in rat liver

    Ken-ichiro Minato;Yoshiaki Miyake;Syuichi Fukumoto;Kanefumi Yamamoto

  • Regulation of branched-chain amino acid catabolism: nutritional and hormonal regulation of activity and expression of the branched-chain alpha-keto acid dehydrogenase kinase.

    Yoshiharu Shimomura;Mariko Obayashi;Taro Murakami;Robert A. Harris

  • Studies on the regulation of the mitochondrial α-ketoacid dehydrogenase complexes and their kinases

    Robert A. Harris;John W. Hawes;Kirill M. Popov;Yu Zhao

  • Branched-chain amino acid catabolism in exercise and liver disease.

    Yoshiharu Shimomura;Takashi Honda;Makoto Shiraki;Taro Murakami

  • A new family of protein kinases--the mitochondrial protein kinases.

    Robert A. Harris;Kirill M. Popov;Yu Zhao;Natalia Y. Kedishvili

  • PGC-1α-mediated branched-chain amino acid metabolism in the skeletal muscle

    Yukino Hatazawa;Miki Tadaishi;Yuta Nagaike;Akihito Morita

  • Primary Structure and Tissue-specific Expression of Human β-Hydroxyisobutyryl-coenzyme A Hydrolase

    John W. Hawes;Jerzy Jaskiewicz;Yoshiharu Shimomura;Boli Huang

  • Distribution of Key Enzymes of Branched-chain Amino Acid Metabolism in Glial and Neuronal Cells in Culture

    M. Gabriele Bixel;Yoshiharu Shimomura;Susan M. Hutson;Bernd Hamprecht

  • Leucine and Protein Metabolism in Obese Zucker Rats

    Pengxiang She;Kristine C. Olson;Yoshihiro Kadota;Ayami Inukai

  • Purification and partial characterization of 3-hydroxyisobutyryl-coenzyme A hydrolase of rat liver.

    Yoshiharu Shimomura;Taro Murakami;Noriaki Fujitsuka;Naoya Nakai

  • Regulation of the branched-chain α-ketoacid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease

    Robert A. Harris;Bei Zhang;Gary W. Goodwin;Martha J. Kuntz

  • Preparation of a Monoclonal Antibody to Nϵ-(Hexanonyl)lysine: Application to the Evaluation of Protective Effects of Flavonoid Supplementation against Exercise-Induced Oxidative Stress in Rat Skeletal Muscle

    Yoji Kato;Yoshiaki Miyake;Kanefumi Yamamoto;Yoshiharu Shimomura

  • Regulation of Branched-Chain α-Keto Acid Dehydrogenase Kinase Expression in Rat Liver

    Robert A. Harris;Rumi Kobayashi;Taro Murakami;Taro Murakami;Yoshiharu Shimomura

Frequent Co-Authors

Robert A. Harris
Robert A. Harris Indiana University
Takayuki Ozawa
Takayuki Ozawa Nagoya University
Hidemi Goto
Hidemi Goto Nagoya University
Tomohiro Tamura
Tomohiro Tamura National Institute of Advanced Industrial Science and Technology
David W. Crabb
David W. Crabb Indiana University
Masashi Tanaka
Masashi Tanaka Juntendo University
Robert A. Harris
Robert A. Harris Karolinska Institute
Yoshihiro Ogawa
Yoshihiro Ogawa Kyushu University
Akimasa Nakao
Akimasa Nakao Nagoya University
Toshihiko Osawa
Toshihiko Osawa Nagoya University

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