World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
11708
World Ranking
12056
National Ranking
824

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

The scientist’s investigation covers issues in Biochemistry, Proteasome, Molecular biology, Protein subunit and Ubiquitin. His research in Proteasome intersects with topics in Cell culture, Cytoplasm, Proteolysis, Peptide sequence and c-jun. The study incorporates disciplines such as Gene expression, Recombinant DNA, Expression vector, Escherichia coli and Gene in addition to Molecular biology.

His study in the field of Gene silencing is also linked to topics like RNA silencing. The concepts of his Protein subunit study are interwoven with issues in Biophysics, Molecular cloning and Interferon gamma. His biological study spans a wide range of topics, including Protein structure and Cell biology.

His most cited work include:

  • Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination. (667 citations)
  • Interferon-gamma induces different subunit organizations and functional diversity of proteasomes (294 citations)
  • Less body fat accumulation in rats fed a safflower oil diet than in rats fed a beef tallow diet. (256 citations)

What are the main themes of his work throughout his whole career to date?

Tomohiro Tamura focuses on Biochemistry, Internal medicine, Gene, Molecular biology and Rhodococcus. Proteasome, Thermoplasma acidophilum, Protein subunit, Enzyme and Escherichia coli are among the areas of Biochemistry where the researcher is concentrating his efforts. His study in Proteasome is interdisciplinary in nature, drawing from both Ubiquitin, Protein degradation and Proteolysis.

His studies deal with areas such as Mutant and Stereochemistry as well as Enzyme. His studies in Internal medicine integrate themes in fields like Endocrinology and Oncology. In his research, Rhodococcus erythropolis and Bacteria is intimately related to Microbiology, which falls under the overarching field of Rhodococcus.

He most often published in these fields:

  • Biochemistry (56.12%)
  • Internal medicine (17.91%)
  • Gene (23.28%)

What were the highlights of his more recent work (between 2015-2021)?

  • Internal medicine (17.91%)
  • Lung cancer (9.55%)
  • Oncology (7.76%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Internal medicine, Lung cancer, Oncology, Biochemistry and Pathology. When carried out as part of a general Internal medicine research project, his work on Retrospective cohort study, Asthma and Afatinib is frequently linked to work in In patient, therefore connecting diverse disciplines of study. His Lung cancer research incorporates themes from Radiology, Cancer, Carcinoma and Lung.

Enzyme, Gene, Pseudonocardia autotrophica, Vitamin and Dihomo-γ-linolenic acid are among the areas of Biochemistry where Tomohiro Tamura concentrates his study. His Enzyme study which covers Burkholderia that intersects with Triacylglycerol lipase, Docking and Gene expression. In the subject of general Gene, his work in Actinobacteria, Messenger RNA and Sequence is often linked to Synonymous substitution, thereby combining diverse domains of study.

Between 2015 and 2021, his most popular works were:

  • Prevalence, Molecular Characterization, and Antimicrobial Susceptibility of Methicillin-Resistant Staphylococcus aureus Isolated from Milk and Dairy Products. (36 citations)
  • Anodized gold surface enables mediator-free and low-overpotential electrochemical oxidation of NADH: A facile method for the development of an NAD+-dependent enzyme biosensor (13 citations)
  • Chemoenzymatically prepared konjac ceramide inhibits NGF-induced neurite outgrowth by a semaphorin 3A-like action. (9 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

His primary scientific interests are in Biochemistry, Gene, Neurite, Phosphorylation and Cell biology. Tomohiro Tamura conducts interdisciplinary study in the fields of Biochemistry and Burkholderia stabilis through his works. His study on Neurite also encompasses disciplines like

  • Signal transduction that connect with fields like Ligand, Receptor, Cell surface receptor and HaCaT,
  • Semaphorin that intertwine with fields like Collapsin response mediator protein family.

His Enzyme research integrates issues from Promoter, Gene expression, Extracellular, Expression vector and Burkholderia. His work carried out in the field of Escherichia coli brings together such families of science as Messenger RNA, Computational biology and Recombinant DNA. Tomohiro Tamura has included themes like Plasmid, Bacteriocin, Structural gene, Molecular biology and Peptide sequence in his Heterologous study.

Best Publications

  • Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination.

    Yasuko Murakami;Senya Matsufuji;Takaaki Kameji;Shin-Ichi Hayashi

  • Interferon-gamma induces different subunit organizations and functional diversity of proteasomes

    Masashi Aki;Naoki Shimbara;Makoto Takashina;Kinya Akiyama

  • Less body fat accumulation in rats fed a safflower oil diet than in rats fed a beef tallow diet.

    Yoshiharu Shimomura;Tomohiro Tamura;Masashige Suzuki

  • Specific organ metastases and survival in metastatic non‑small‑cell lung cancer

    Tomohiro Tamura;Koichi Kurishima;Kensuke Nakazawa;Katsunori Kagohashi

  • Self-compartmentalizing proteases

    Andrei Lupas;John M. Flanagan;Tomohiro Tamura;Wolfgang Baumeister

  • Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction.

    Yujiro Hayashi;Hiroaki Gotoh;Tomohiro Tamura;Hirofumi Yamaguchi

  • Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

    H. Hisamatsu;N. Shimbara;Y. Saito;P. Kristensen

  • The first characterization of a eubacterial proteasome: the 20S complex of Rhodococcus

    Tomohiro Tamura;Istvén Nagy;Andrei Lupas;Friedrich Lottspeich

  • cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y

    Kin-Ya Akiyama;Kim-Ya Yokota;Susumu Kagawa;Naoki Shimbara

  • Proteasomes: protein and gene structures.

    K Tanaka;T Tamura;T Yoshimura;A Ichihara

  • Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth factor 8-associated microvesicles.

    Naohito Aoki;Naohito Aoki;Shinji Jin-no;Yoshimi Nakagawa;Noriyuki Asai

  • Specific organ metastases and survival in small cell lung cancer.

    Kensuke Nakazawa;Koichi Kurishima;Tomohiro Tamura;Katsunori Kagohashi

  • Molecular characterization of the "26S" proteasome complex from rat liver

    T. Yoshimura;K. Kameyama;T. Takagi;A. Ikai

  • Degradation of c-Fos by the 26S proteasome is accelerated by c-Jun and multiple protein kinases.

    C Tsurumi;N Ishida;T Tamura;A Kakizuka

  • Possible mechanism of nuclear translocation of proteasomes.

    Keiji Tanaka;Tetsuro Yoshimura;Tomohiro Tamura;Tsutomu Fujiwara

  • Isolation and characterization of a rolling-circle-type plasmid from Rhodococcus erythropolis and application of the plasmid to multiple-recombinant-protein expression.

    Nobutaka Nakashima;Tomohiro Tamura;Tomohiro Tamura

  • The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together

    Ganesh Ramnath Pathare;István Nagy;Stefan Bohn;Pia Unverdorben

  • Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers

    Naoki Fujitani;Jun ichi Furukawa;Kayo Araki;Tsuyoshi Fujioka

  • ATP-dependent reversible association of proteasomes with multiple protein components to form 26S complexes that degrade ubiquitinated proteins in human HL-60 cells

    Etsuko Orino;Keiji Tanaka;Tomohiro Tamura;Saburo Sone

  • Replacement of proteasome subunits X and Y by LMP7 and LMP2 induced by interferon-γ for acquirement of the functional diversity responsible for antigen processing

    Kinya Akiyama;Susumu Kagawa;Tomohiro Tamura;Naoki Shimbara

Frequent Co-Authors

Akira Ichihara
Akira Ichihara University of Tokushima
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Nobuyuki Hizawa
Nobuyuki Hizawa University of Tsukuba
Wolfgang Baumeister
Wolfgang Baumeister Max Planck Society
Isao Tanaka
Isao Tanaka Hokkaido University
Yoshiharu Shimomura
Yoshiharu Shimomura Nagoya University
Yasuyuki Igarashi
Yasuyuki Igarashi Hokkaido University
Min Yao
Min Yao Hokkaido University
Chin Ha Chung
Chin Ha Chung Seoul National University
Yoichi Kamagata
Yoichi Kamagata National Institute of Advanced Industrial Science and Technology

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