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Neuroscience

D-Index
43
Citations
8983
World Ranking
7337
National Ranking
3171

Overview

Robert A. Pearce is affiliated with the University of Wisconsin-Madison in the United States. Their research spans multiple fields primarily in neuroscience and medicine, with significant contributions to cognitive neuroscience, critical care and intensive care medicine, developmental neuroscience, cellular and molecular neuroscience, and anesthesiology and pain medicine.

Their work focuses on key topics including intensive care unit cognitive disorders, anesthesia and neurotoxicity research, anesthesia and sedative agents, neuroscience and neuropharmacology research, neural dynamics and brain function, memory and neural mechanisms, and neuroinflammation and neurodegeneration mechanisms.

Robert A. Pearce has published extensively in several venues, with frequent publications in the following journals:

  • British Journal of Anaesthesia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journals of Gerontology Series A
  • BJA Open
  • Brain Communications

Among recent papers, the following stand out with details on title, year, and venue:

  • Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study (2022, British Journal of Anaesthesia)
  • Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study (2020, British Journal of Anaesthesia)
  • GABA facilitates spike propagation through branch points of sensory axons in the spinal cord (2022, Nature Neuroscience)
  • Distinct EEG signatures differentiate unconsciousness and disconnection during anaesthesia and sleep (2022, British Journal of Anaesthesia)
  • Cohort Analysis of the Association of Delirium Severity With Cerebrospinal Fluid Amyloid-Tau-Neurodegeneration Pathologies (2021, The Journals of Gerontology Series A)

Frequent collaborators in their research include:

  • Richard Lennertz
  • Robert D. Sanders
  • Cameron Casey
  • David Kunkel
  • Margaret Parker

Best Publications

  • Specification of motoneurons from human embryonic stem cells

    Xue Jun Li;Zhong Wei Du;Ewa D. Zarnowska;Matthew Pankratz

  • Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness

    Fabio Ferrarelli;Marcello Massimini;Simone Sarasso;Adenauer Casali

  • Diversity of inhibitory neurotransmission through GABAA receptors

    Istvan Mody;Robert A. Pearce

  • Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem Cells

    Yiping Yan;Dali Yang;Ewa D. Zarnowska;Zhongwei Du

  • Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology

    M A McCall;R G Gregg;R R Behringer;M Brenner

  • Functional Neural Development from Human Embryonic Stem Cells: Accelerated Synaptic Activity via Astrocyte Coculture

    Michael Johnson;Jason P. Weick;Robert A. Pearce;Su Chun Zhang

  • Physiological evidence for two distinct GABAA responses in rat hippocampus

    Robert A. Pearce

  • Networks of interneurons with fast and slow gamma-aminobutyric acid type A (GABAA) kinetics provide substrate for mixed gamma-theta rhythm.

    John A. White;Matthew I. Banks;Robert A. Pearce;Nancy J. Kopell

  • Dual Actions of Volatile Anesthetics on GABAA IPSCs: Dissociation of Blocking and Prolonging Effects

    Matthew I. Banks;Robert A. Pearce

  • Hyperpolarization-activated cation current (Ih) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem

    M. I. Banks;R. A. Pearce;P. H. Smith

  • Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study.

    Unknown

  • The Synaptic Basis of GABAA,slow

    Matthew I. Banks;Tong-Bin Li;Robert A. Pearce

  • Kinetic Differences between Synaptic and Extrasynaptic GABA A Receptors in CA1 Pyramidal Cells

    Matthew I. Banks;Robert A. Pearce

  • Interactions between Distinct GABAA Circuits in Hippocampus

    Matthew I Banks;John A White;Robert A Pearce

  • GABAA,slow: causes and consequences

    Marco Capogna;Robert A. Pearce

  • Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study.

    Tyler Ballweg;Marissa White;Margaret Parker;Cameron Casey

  • GABAA Receptor α5 Subunits Contribute to GABAA,slow Synaptic Inhibition in Mouse Hippocampus

    Ewa D. Zarnowska;Ruth Keist;Uwe Rudolph;Uwe Rudolph;Robert A. Pearce

  • Determination of diffusion and partition coefficients of propofol in rat brain tissue: implications for studies of drug action in vitro

    J.A. Gredell;P.A. Turnquist;M.B. MacIver;R.A. Pearce

  • Effect of Volatile Anesthetics on Synaptic Transmission in the Rat Hippocampus

    Robert A. Pearce;Janet L. Stringer;Eric W. Lothman

  • Determination of the EC50 amnesic concentration of etomidate and its diffusion profile in brain tissue: implications for in vitro studies.

    Claudia Benkwitz;Mark Liao;Michael J. Laster;James M. Sonner

  • GABAA-Mediated IPSCs in Piriform Cortex Have Fast and Slow Components With Different Properties and Locations on Pyramidal Cells

    A. Kapur;R. A. Pearce;W. W. Lytton;L. B. Haberly

  • An Isoflurane- and Alcohol-Insensitive Mutant GABAA Receptor α1 Subunit with Near-Normal Apparent Affinity for GABA: Characterization in Heterologous Systems and Production of Knockin Mice

    C. M. Borghese;D. F. Werner;N. Topf;N. V. Baron

Frequent Co-Authors

Gregg E. Homanics
Gregg E. Homanics University of Pittsburgh
Michael E. Talkowski
Michael E. Talkowski Harvard University
Kaj Blennow
Kaj Blennow University of Gothenburg
Giulio Tononi
Giulio Tononi University of Wisconsin–Madison
John A. White
John A. White Boston University
Michael T. Alkire
Michael T. Alkire University of California, Irvine
Janet L. Stringer
Janet L. Stringer Baylor College of Medicine
Max B. Kelz
Max B. Kelz University of Pennsylvania
Michael S. Fanselow
Michael S. Fanselow University of California, Los Angeles
Neil L. Harrison
Neil L. Harrison Columbia University

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