D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 96 Citations 32,628 376 World Ranking 5878 National Ranking 3243

Research.com Recognitions

Awards & Achievements

1982 - Fellow of the American Association for the Advancement of Science (AAAS)

Fellow of The Academy of Medical Sciences, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Surgery
  • Gene

Mervyn Maze mainly investigates Anesthesia, Dexmedetomidine, Pharmacology, Anesthetic and Sedative. Mervyn Maze has researched Anesthesia in several fields, including Randomized controlled trial, Postoperative cognitive dysfunction and Delirium. His studies deal with areas such as Agonist, Endocrinology, Medetomidine and Internal medicine as well as Dexmedetomidine.

His Pharmacology study integrates concerns from other disciplines, such as Adrenergic receptor, Mechanism of action, Glutamate receptor, Antagonist and Pathology. His research integrates issues of Nitrous oxide and Neurocognitive Dysfunction in his study of Anesthetic. His work deals with themes such as Hypnotic, Environmental air flow and Sympatholytic, which intersect with Sedative.

His most cited work include:

  • Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients: The MENDS Randomized Controlled Trial (982 citations)
  • Alpha-2 adrenoceptor agonists: defining the role in clinical anesthesia. (632 citations)
  • Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. (572 citations)

What are the main themes of his work throughout his whole career to date?

Mervyn Maze mostly deals with Anesthesia, Pharmacology, Dexmedetomidine, Internal medicine and Endocrinology. His research in Anesthesia intersects with topics in Randomized controlled trial, Neuroprotection and Nociception. His work in Pharmacology addresses issues such as Adrenergic receptor, which are connected to fields such as Alpha.

His research on Dexmedetomidine also deals with topics like

  • Agonist and related Clonidine,
  • Sedative, which have a strong connection to Sedation. His Endocrinology research is multidisciplinary, relying on both Adrenergic and Mechanism of action. His Anesthetic study combines topics in areas such as Halothane and Isoflurane.

He most often published in these fields:

  • Anesthesia (42.20%)
  • Pharmacology (28.64%)
  • Dexmedetomidine (27.11%)

What were the highlights of his more recent work (between 2012-2021)?

  • Anesthesia (42.20%)
  • Cognitive decline (7.42%)
  • Perioperative (5.63%)

In recent papers he was focusing on the following fields of study:

Anesthesia, Cognitive decline, Perioperative, Intensive care medicine and Randomized controlled trial are his primary areas of study. His study in Dexmedetomidine and Anesthetic falls under the purview of Anesthesia. His Dexmedetomidine study is related to the wider topic of Pharmacology.

His studies in Cognitive decline integrate themes in fields like Inflammation, Proinflammatory cytokine, Neuroinflammation and Metabolic syndrome. His Inflammation study incorporates themes from Hippocampal formation, Endocrinology and Pathology. His work in Randomized controlled trial tackles topics such as Neuroprotection which are related to areas like Neurologic injury.

Between 2012 and 2021, his most popular works were:

  • Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial. (298 citations)
  • Bundled Payments in Total Joint Arthroplasty: Targeting Opportunities for Quality Improvement and Cost Reduction (270 citations)
  • Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018 (127 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Surgery
  • Gene

Mervyn Maze focuses on Anesthesia, Cognitive decline, Randomized controlled trial, Postoperative cognitive dysfunction and Surgery. His Anesthesia research incorporates elements of Analysis of variance, Clinical trial and Metabolic syndrome. His study in Cognitive decline is interdisciplinary in nature, drawing from both Hippocampal formation, Endocrinology, Inflammation and Innate immune system.

His Randomized controlled trial research is multidisciplinary, incorporating perspectives in Inhalation, Dexmedetomidine, Intensive care and Out of hospital cardiac arrest. His work in Dexmedetomidine covers topics such as Neurologic injury which are related to areas like Neuroprotection. His work on Methyllycaconitine, Oxidative stress, Neuroinflammation and Agonist is typically connected to Nicotinamide adenine dinucleotide phosphate as part of general Internal medicine study, connecting several disciplines of science.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients: The MENDS Randomized Controlled Trial

Pratik P. Pandharipande;Brenda T. Pun;Daniel L. Herr;Mervyn Maze.
JAMA (2007)

1537 Citations

The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects.

Laura E. Nelson;Jun Lu;Tianzhi Guo;Clifford B. Saper.
Anesthesiology (2003)

1028 Citations

Alpha-2 adrenoceptor agonists: defining the role in clinical anesthesia.

Mervyn Maze;William Tranquilli.
Anesthesiology (1991)

1011 Citations

Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes.

Byron C. Bloor;Denham S. Ward;Jon P. Belleville;Mervyn Maze.
Anesthesiology (1992)

954 Citations

Clinical Uses of α2-Adrenergic Agonists

Takahiko Kamibayashi;Mervyn Maze.
Anesthesiology (2000)

857 Citations

Postoperative cognitive dysfunction after noncardiac surgery: a systematic review.

Stanton Newman;Jan Stygall;Shashivadan Hirani;Shahzad Shaefi.
Anesthesiology (2007)

810 Citations

Role of interleukin-1beta in postoperative cognitive dysfunction.

Mario Cibelli;Antonio Rei Fidalgo;Niccolò Terrando;Niccolò Terrando;Daqing Ma.
Annals of Neurology (2010)

761 Citations

Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate.

Jon P. Belleville;Denham S. Ward;Byron C. Bloor;Mervyn Maze.
Anesthesiology (1992)

709 Citations

Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline.

Niccolò Terrando;Claudia Monaco;Daqing Ma;Brian M. J. Foxwell.
Proceedings of the National Academy of Sciences of the United States of America (2010)

642 Citations

The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway.

L. E. Nelson;T. Z. Guo;J. Lu;C. B. Saper.
Nature Neuroscience (2002)

629 Citations

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