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Medicine

D-Index
103
Citations
40219
World Ranking
7347
National Ranking
3847

Research.com Recognitions

  • 1982 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Mervyn Maze is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine and Neuroscience, with significant contributions in subfields such as Critical Care and Intensive Care Medicine, Developmental Neuroscience, Neurology, Cardiology and Cardiovascular Medicine, and Anesthesiology and Pain Medicine.

Their scholarly output includes numerous publications focused on topics such as Intensive Care Unit Cognitive Disorders, Anesthesia and Neurotoxicity Research, Cardiac, Anesthesia and Surgical Outcomes, Anesthesia and Sedative Agents, Neuroinflammation and Neurodegeneration Mechanisms, Traumatic Brain Injury and Neurovascular Disturbances, and Cardiac Arrest and Resuscitation.

Recent papers authored or coauthored by Mervyn Maze include:

  • The Role of Microglia in Perioperative Neuroinflammation and Neurocognitive Disorders, 2021, Frontiers in Aging Neuroscience
  • Dexmedetomidine Exerts an Anti-inflammatory Effect via α2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice, 2020, Anesthesiology
  • Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia, 2020, European Journal of Anaesthesiology
  • Effect of Intraoperative Dexmedetomidine on Recovery of Gastrointestinal Function After Abdominal Surgery in Older Adults, 2021, JAMA Network Open
  • Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice, 2020, British Journal of Anaesthesia

Mervyn Maze frequently collaborates with several researchers, including Sarah Saxena, Véronique Kruys, Xiaomei Feng, Jòseph Vamecq, and Jun Hu.

Their work is published predominantly in journals such as the British Journal of Anaesthesia, Frontiers in Aging Neuroscience, Anesthesiology, European Journal of Anaesthesiology, and Cells.

Professional recognition includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 1982 and a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients: The MENDS Randomized Controlled Trial

    Pratik P. Pandharipande;Brenda T. Pun;Daniel L. Herr;Mervyn Maze

  • The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects.

    Laura E. Nelson;Jun Lu;Tianzhi Guo;Clifford B. Saper

  • Alpha-2 adrenoceptor agonists: defining the role in clinical anesthesia.

    Mervyn Maze;William Tranquilli

  • Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes.

    Byron C. Bloor;Denham S. Ward;Jon P. Belleville;Mervyn Maze

  • Role of interleukin-1beta in postoperative cognitive dysfunction.

    Mario Cibelli;Antonio Rei Fidalgo;Niccolò Terrando;Niccolò Terrando;Daqing Ma

  • Clinical Uses of α2-Adrenergic Agonists

    Takahiko Kamibayashi;Mervyn Maze

  • Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018

    L. Evered;L. Evered;B. Silbert;B. Silbert;D.S. Knopman;D.A. Scott;D.A. Scott

  • Postoperative cognitive dysfunction after noncardiac surgery: a systematic review.

    Stanton Newman;Jan Stygall;Shashivadan Hirani;Shahzad Shaefi

  • Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline.

    Niccolò Terrando;Claudia Monaco;Daqing Ma;Brian M. J. Foxwell

  • Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate.

    Jon P. Belleville;Denham S. Ward;Byron C. Bloor;Mervyn Maze

  • Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial.

    Xian Su;Zhao-Ting Meng;Xin-Hai Wu;Fan Cui

  • The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway.

    L. E. Nelson;T. Z. Guo;J. Lu;C. B. Saper

  • Resolving postoperative neuroinflammation and cognitive decline

    Niccolò Terrando;Lars I Eriksson;Lars I Eriksson;Jae Kyu Ryu;Ting Yang

  • Postoperative impairment of cognitive function in rats: a possible role for cytokine-mediated inflammation in the hippocampus.

    Yanjie Wan;Jing Xu;Daqing Ma;Yinming Zeng

  • Dexmedetomidine attenuates isoflurane-induced neurocognitive impairment in neonatal rats.

    Robert D. Sanders;Jing Xu;Yi Shu;Adam Januszewski

  • A Hypnotic Response to Dexmedetomidine, an α2 Agonist, Is Mediated in the Locus Coerüleus in Rats

    Christiane Correa-Sales;Bradford C. Rabin;Mervyn Maze

  • Bundled Payments in Total Joint Arthroplasty: Targeting Opportunities for Quality Improvement and Cost Reduction

    Kevin J. Bozic;Lorrayne Ward;Thomas P. Vail;Mervyn Maze

  • Dexmedetomidine injection into the Locus ceruleus produces antinociception

    Tian-Zhi Guo;Jian-Yu Jiang;Ann E. Buttermann;Mervyn Maze

  • Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo.

    Parul P. Lakhlani;Leigh B. MacMillan;Tian Zhi Guo;Brian A. McCool

  • Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial

    Pratik P Pandharipande;Robert D Sanders;Timothy D Girard;Timothy D Girard;Stuart McGrane

Frequent Co-Authors

Daqing Ma
Daqing Ma Imperial College London
Nicholas P. Franks
Nicholas P. Franks Imperial College London
Marc Feldmann
Marc Feldmann University of Oxford
Lars Eriksson
Lars Eriksson Linköping University
Pratik P. Pandharipande
Pratik P. Pandharipande Vanderbilt University Medical Center
Jing Xu
Jing Xu Zhejiang University
Pierre Gressens
Pierre Gressens Université Paris Cité
Brian K. Kobilka
Brian K. Kobilka Stanford University
William L. Young
William L. Young University of California, San Francisco
Steven L. Shafer
Steven L. Shafer Stanford University

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