World's Best Scientists 2026 revealed!

Overview

Ivaylo Ivanov is affiliated with Georgia State University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in molecular biology as a core subfield. Other areas of their research include infectious diseases, immunology, genetics, and neurology.

The scientist's work explores a variety of specialized topics, among which DNA repair mechanisms and RNA modifications related to cancer are prominent. Other research interests encompass DNA and nucleic acid chemistry, mechanisms of RNA and protein synthesis, genomics and chromatin dynamics, RNA research and splicing, and cancer-related gene regulation.

Ivaylo Ivanov has coauthored publications with several frequent collaborators, which include Chunli Yan, Susan E. Tsutakawa, John A. Tainer, Thomas Dodd, and Jina Yu.

Their publication record features articles in well-regarded journals, notably including multiple works in Nature Communications and contributions to the Journal of Biological Chemistry, Pharmacia, Proceedings of the National Academy of Sciences, and the Journal of Chemical Information and Modeling.

Key recent publications include:

  • Polymerization and editing modes of a high-fidelity DNA polymerase are linked by a well-defined path, 2020, Nature Communications
  • Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6, 2020, Proceedings of the National Academy of Sciences
  • Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair, 2020, DNA Repair
  • Simulation-Based Methods for Model Building and Refinement in Cryoelectron Microscopy, 2020, Journal of Chemical Information and Modeling
  • A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair, 2022, Nucleic Acids Research

Best Publications

  • Hydrogen bonding in water.

    Bin Chen;Ivaylo Ivanov;Michael L. Klein;Michele Parrinello

  • Near-atomic resolution visualization of human transcription promoter opening

    Yuan He;Chunli Yan;Jie Fang;Carla Inouye

  • An electrochemical clamp assay for direct, rapid analysis of circulating nucleic acids in serum

    Jagotamoy Das;Ivaylo Ivanov;Laura Montermini;Janusz Rak

  • Synthetic mimics of antimicrobial peptides

    Abhigyan Som;Satyavani Vemparala;Ivaylo Ivanov;Gregory N. Tew

  • DNA Clutch Probes for Circulating Tumor DNA Analysis

    Jagotamoy Das;Ivaylo Ivanov;Edward H. Sargent;Shana O. Kelley

  • Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3.

    Ivaylo P. Ivanov;Andreas Rohrwasser;Daniel A. Terreros;Raymond F. Gesteland

  • Characterizing Loop Dynamics and Ligand Recognition in Human- and Avian-Type Influenza Neuraminidases via Generalized Born Molecular Dynamics and End-Point Free Energy Calculations

    Rommie E. Amaro;Xiaolin Cheng;Ivaylo Ivanov;Dong Xu

  • Nanoparticle‐Mediated Binning and Profiling of Heterogeneous Circulating Tumor Cell Subpopulations

    Reza M. Mohamadi;Justin D. Besant;Adam Mepham;Brenda Green

  • A second mammalian antizyme: conservation of programmed ribosomal frameshifting.

    Ivaylo P. Ivanov;Raymond F. Gesteland;Raymond F. Gesteland;John F. Atkins;John F. Atkins

  • Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia

    Jing Li;Shanshan Li;Jianshuang Guo;Qiuying Li

  • Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes

    Susan E. Tsutakawa;David S. Shin;Clifford D. Mol;Tadahide Izumi;Tadahide Izumi

  • Solvation structure and mobility mechanism of OH-: A car-parrinello molecular dynamics investigation of alkaline solutions

    Bin Chen;Ivaylo Ivanov;Jung Mee Park;Michele Parrinello,§,‖ and

  • A new structural framework for integrating replication protein A into DNA processing machinery

    Chris A. Brosey;Chunli Yan;Susan E. Tsutakawa;William T. Heller

  • Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV.

    Ivaylo Ivanov;John A. Tainer;J. Andrew McCammon

  • Characterization of nonbiological antimicrobial polymers in aqueous solution and at water-lipid interfaces from all-atom molecular dynamics.

    Ivaylo Ivanov;Satyavani Vemparala;Vojislava Pophristic;Kenichi Kuroda

  • First-Principles Study of Aqueous Hydroxide Solutions

    Bin Chen;Jung Mee Park;Ivaylo Ivanov;Gloria Tabacchi

  • Roles of polyamines in translation

    Thomas E. Dever;Ivaylo P. Ivanov

  • The Design and Evaluation of Heparin‐Binding Foldamers

    Sungwook Choi;Dylan J. Clements;Vojislava Pophristic;Ivaylo Ivanov

  • Diamidine compounds for selective inhibition of protein arginine methyltransferase 1.

    Leilei Yan;Chunli Yan;Kun Qian;Hairui Su

  • Nanosecond-Timescale Conformational Dynamics of the Human α7 Nicotinic Acetylcholine Receptor

    Xiaolin Cheng;Ivaylo Ivanov;Hailong Wang;Steven M. Sine

Frequent Co-Authors

John F. Atkins
John F. Atkins University College Cork
John A. Tainer
John A. Tainer The University of Texas MD Anderson Cancer Center
Raymond F. Gesteland
Raymond F. Gesteland University of Utah
Michael L. Klein
Michael L. Klein Temple University
J. Andrew McCammon
J. Andrew McCammon University of California, San Diego
Eva Nogales
Eva Nogales University of California, Berkeley
Shana O. Kelley
Shana O. Kelley Northwestern University
Edward H. Sargent
Edward H. Sargent Northwestern University
Matthew S. Sachs
Matthew S. Sachs Texas A&M University
William F. DeGrado
William F. DeGrado University of California, San Francisco

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