D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 101 Citations 35,782 263 World Ranking 286 National Ranking 172

Research.com Recognitions

Awards & Achievements

2015 - Member of the National Academy of Sciences

2009 - Fellow of the American Academy of Arts and Sciences

2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

Alan G. Hinnebusch focuses on Biochemistry, Initiation factor, Genetics, Eukaryotic translation and Eukaryotic initiation factor. Biochemistry is represented through his Saccharomyces cerevisiae, Protein biosynthesis, eIF2B, Phosphorylation and Translation research. His Initiation factor research includes themes of Translational regulation, EIF1, Protein subunit, G alpha subunit and Molecular biology.

He has included themes like Guanine nucleotide exchange factor and Computational biology in his Eukaryotic translation study. His Eukaryotic initiation factor research is multidisciplinary, incorporating perspectives in Eukaryotic translation initiation factor 4 gamma, Prokaryotic initiation factor, Internal ribosome entry site, Eukaryotic Ribosome and Cell biology. His study in Cell biology is interdisciplinary in nature, drawing from both eIF2, Eukaryotic Initiation Factor-2, EIF4A1 and Transfer RNA, Eukaryotic Large Ribosomal Subunit.

His most cited work include:

  • Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets (2218 citations)
  • Translational regulation of GCN4 and the general amino acid control of yeast. (971 citations)
  • Transcriptional Profiling Shows that Gcn4p Is a Master Regulator of Gene Expression during Amino Acid Starvation in Yeast (619 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Eukaryotic translation, Biochemistry, Genetics and Translation. The concepts of his Cell biology study are interwoven with issues in Molecular biology, Messenger RNA, EIF4E, Ribosome and Transcription preinitiation complex. His research in Molecular biology intersects with topics in RNA polymerase II and Protein subunit.

His Eukaryotic translation study combines topics from a wide range of disciplines, such as EIF1, Eukaryotic Small Ribosomal Subunit, eIF4A, Polysome and Initiation factor. Alan G. Hinnebusch has researched Initiation factor in several fields, including Eukaryotic translation initiation factor 4 gamma, Translational regulation, eIF2, Eukaryotic Ribosome and Eukaryotic initiation factor. The various areas that Alan G. Hinnebusch examines in his Translation study include Open reading frame and Transfer RNA.

He most often published in these fields:

  • Cell biology (41.91%)
  • Eukaryotic translation (31.25%)
  • Biochemistry (28.31%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (41.91%)
  • Start codon (18.75%)
  • Eukaryotic translation (31.25%)

In recent papers he was focusing on the following fields of study:

Alan G. Hinnebusch mainly investigates Cell biology, Start codon, Eukaryotic translation, Translation and Messenger RNA. His Cell biology research incorporates themes from Eukaryotic Ribosome, Ribosome, eIF4A, Initiation factor and Transcription preinitiation complex. His Eukaryotic translation research is multidisciplinary, incorporating elements of Eukaryotic Small Ribosomal Subunit and Eukaryotic initiation factor.

Eukaryotic initiation factor is a subfield of Genetics that Alan G. Hinnebusch investigates. His Translation research includes elements of Open reading frame, Reprogramming and Saccharomyces cerevisiae. The Messenger RNA study combines topics in areas such as Molecular biology and Yeast.

Between 2013 and 2021, his most popular works were:

  • Translational control by 5′-untranslated regions of eukaryotic mRNAs (492 citations)
  • The Scanning Mechanism of Eukaryotic Translation Initiation (464 citations)
  • Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex (145 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

Nahum Sonenberg;Alan G. Hinnebusch.
Cell (2009)

3222 Citations

Translational regulation of GCN4 and the general amino acid control of yeast.

Alan G Hinnebusch.
Annual Review of Microbiology (2005)

1638 Citations

Transcriptional Profiling Shows that Gcn4p Is a Master Regulator of Gene Expression during Amino Acid Starvation in Yeast

Krishnamurthy Natarajan;Michael R. Meyer;Belinda M. Jackson;David Slade.
Molecular and Cellular Biology (2001)

1005 Citations

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

Thomas E. Dever;Lan Feng;Ronald C. Wek;A.Mark Cigan.
Cell (1992)

888 Citations

The Scanning Mechanism of Eukaryotic Translation Initiation

Alan G Hinnebusch.
Annual Review of Biochemistry (2014)

842 Citations

Translational Regulation of Yeast GCN4 A WINDOW ON FACTORS THAT CONTROL INITIATOR-tRNA BINDING TO THE RIBOSOME

Alan G. Hinnebusch.
Journal of Biological Chemistry (1997)

760 Citations

Translational control by 5′-untranslated regions of eukaryotic mRNAs

Alan G. Hinnebusch;Ivaylo P. Ivanov;Nahum Sonenberg.
Science (2016)

712 Citations

Multiple upstream AUG codons mediate translational control of GCN4

Peter P. Mueller;Alan G. Hinnebusch.
Cell (1986)

699 Citations

Evidence for translational regulation of the activator of general amino acid control in yeast.

Alan G. Hinnebusch.
Proceedings of the National Academy of Sciences of the United States of America (1984)

559 Citations

Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain.

Jinsheng Dong;Hongfang Qiu;Minerva Garcia-Barrio;James T. Anderson.
Molecular Cell (2000)

548 Citations

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