His main research concerns Initiation factor, Molecular biology, Eukaryotic initiation factor, Biochemistry and Protein biosynthesis. His Initiation factor study combines topics from a wide range of disciplines, such as Eukaryotic translation initiation factor 4 gamma, Polysome and Cap-Binding Protein Complex. His biological study spans a wide range of topics, including Nucleic acid and Cell biology.
His Eukaryotic initiation factor research incorporates themes from EIF4E, EIF4A1 and TAF4. His Protein biosynthesis research integrates issues from Messenger RNP, cDNA library, mRNA surveillance and Repressor. His research in Ribosome intersects with topics in Ribosomal RNA and Protein subunit.
His primary scientific interests are in Initiation factor, Biochemistry, Molecular biology, Eukaryotic initiation factor and Protein biosynthesis. The Initiation factor study combines topics in areas such as Eukaryotic translation, EIF4A1, Protein subunit and Cell biology. His Molecular biology study incorporates themes from RNA, Reticulocyte, Ribosomal RNA, Eukaryotic Initiation Factor-2 and HeLa.
His work investigates the relationship between Eukaryotic initiation factor and topics such as Internal ribosome entry site that intersect with problems in EIF4G. In Protein biosynthesis, John W.B. Hershey works on issues like Polyacrylamide gel electrophoresis, which are connected to Sodium dodecyl sulfate. His studies in Ribosome integrate themes in fields like Transfer RNA and GTP'.
John W.B. Hershey mainly investigates Initiation factor, Cell biology, Eukaryotic initiation factor, Molecular biology and Protein biosynthesis. John W.B. Hershey has researched Initiation factor in several fields, including Eukaryotic translation, Biophysics and Internal ribosome entry site. He interconnects EIF4E, Translational regulation, eIF2 and eIF4A in the investigation of issues within Cell biology.
The concepts of his Eukaryotic initiation factor study are interwoven with issues in Eukaryotic translation initiation factor 4 gamma, EIF4A1, EIF4EBP1 and EIF4G. The study incorporates disciplines such as Translational efficiency, Eukaryotic Small Ribosomal Subunit, Untranslated region and Eukaryotic Ribosome in addition to Molecular biology. His study in Protein biosynthesis is interdisciplinary in nature, drawing from both Amino acid, Cell growth, Protein subunit and Translation, Messenger RNA.
The scientist’s investigation covers issues in Cell biology, Initiation factor, Molecular biology, Eukaryotic initiation factor and Eukaryotic translation. His Initiation factor study focuses on Genetics and Biochemistry. His work in the fields of Messenger RNA, Protein biosynthesis, TOR Serine-Threonine Kinases and Phosphoserine overlaps with other areas such as Tandem mass spectrometry.
His Molecular biology study integrates concerns from other disciplines, such as Internal ribosome entry site, Eukaryotic Small Ribosomal Subunit and Eukaryotic Ribosome. His Eukaryotic initiation factor research incorporates elements of Eukaryotic translation initiation factor 4 gamma, EIF4E and EIF4A1. Eukaryotic translation is a subfield of Translation that he tackles.
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Translational control of gene expression
Nahum Sonenberg;John W. B. Hershey;Michael B. Mathews.
Translational Control in Mammalian Cells
John W. B. Hershey.
Annual Review of Biochemistry (1991)
Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex.
D Etchison;S C Milburn;I Edery;N Sonenberg.
Journal of Biological Chemistry (1982)
Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F.
R. Duncan;S. C. Milburn;J. W. B. Hershey.
Journal of Biological Chemistry (1987)
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
David Shahbazian;Philippe P Roux;Virginie Mieulet;Michael S Cohen.
The EMBO Journal (2006)
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases
Brian Raught;Franck Peiretti;Anne-Claude Gingras;Mark Livingstone.
The EMBO Journal (2004)
The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs.
R. J. Kaufman;M. V. Davies;V. K. Pathak;J. W. B. Hershey.
Molecular and Cellular Biology (1989)
Translational control in biology and medicine
Michael B. Mathews;Nahum Sonenberg;John W. B. Hershey.
Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae.
J. Schnier;H. G. Schwelberger;Z. Smit-Mcbride;Hyun Ah Kang.
Molecular and Cellular Biology (1991)
Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae.
Hyun Ah Kang;J. W. B. Hershey.
Journal of Biological Chemistry (1994)
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