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D-Index & Metrics

Biology and Biochemistry

D-Index
94
Citations
27846
World Ranking
2038
National Ranking
1110

Overview

John W. B. Hershey is affiliated with the University of California, Davis in the United States. Their research spans several interdisciplinary areas, notably within computer science and molecular biology, with a focus on signal processing and genetic engineering.

They have contributed to multiple recent publications, including:

  • Engineered transient and stable overexpression of translation factors eIF3i and eIF3c in CHOK1 and HEK293 cells gives enhanced cell growth associated with increased c-Myc expression and increased recombinant protein synthesis (2020, Metabolic Engineering)
  • Improving Sound Event Detection In Domestic Environments Using Sound Separation (2020, arXiv (Cornell University))
  • Digital Signal Processing memories (2021, Digital Signal Processing)
  • Richard Jackson (1940-2020) - A towering presence in translation (2021, The EMBO Journal)
  • Correction: The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h (2024, Biochemical Journal)

Frequent coauthors collaborating with Hershey include:

  • Anne Roobol
  • Matthew E. Smith
  • Martin J. Carden
  • Anne E. Willis
  • C. Mark Smales

Their work has been published predominantly in the following venues:

  • arXiv (Cornell University)
  • Metabolic Engineering
  • Digital Signal Processing
  • The EMBO Journal
  • Biochemical Journal

John W. B. Hershey's main fields of study are in computer science, particularly signal processing, combined with molecular biology and genetics. Their research subfields include:

  • Signal Processing
  • Molecular Biology
  • Genetics
  • Artificial Intelligence
  • Biomedical Engineering

The primary topics covered in their work comprise:

  • Speech and Audio Processing
  • Viral Infectious Diseases and Gene Expression in Insects
  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering
  • Music and Audio Processing
  • Speech Recognition and Synthesis
  • Acoustic Wave Phenomena Research

Best Publications

  • Translational control of gene expression

    Nahum Sonenberg;John W. B. Hershey;Michael B. Mathews

  • Translational Control in Mammalian Cells

    John W. B. Hershey

  • Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex.

    D Etchison;S C Milburn;I Edery;N Sonenberg

  • Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F.

    R. Duncan;S. C. Milburn;J. W. B. Hershey

  • The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

    David Shahbazian;Philippe P Roux;Virginie Mieulet;Michael S Cohen

  • Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

    Brian Raught;Franck Peiretti;Anne-Claude Gingras;Mark Livingstone

  • The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs.

    R. J. Kaufman;M. V. Davies;V. K. Pathak;J. W. B. Hershey

  • Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae.

    J. Schnier;H. G. Schwelberger;Z. Smit-Mcbride;Hyun Ah Kang

  • Principles of Translational Control: An Overview

    John W.B. Hershey;Nahum Sonenberg;Michael B. Mathews

  • Translational control in biology and medicine

    Michael B. Mathews;Nahum Sonenberg;John W. B. Hershey

  • Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae.

    Hyun Ah Kang;J. W. B. Hershey

  • Protein phosphorylation controls translation rates.

    John W. B. Hershey

  • 2 The Pathway and Mechanism of Eukaryotic Protein Synthesis

    William C. Merrick;John W.B. Hershey

  • Upf1 Phosphorylation Triggers Translational Repression during Nonsense-Mediated mRNA Decay

    Olaf Isken;Yoon Ki Kim;Nao Hosoda;Greg L. Mayeur

  • Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

    Min Zhou;Alan M. Sandercock;Christopher S. Fraser;Gabriela Ridlova

  • Involvement of eukaryotic initiation factor 4A in the cap recognition process.

    I Edery;M Hümbelin;A Darveau;K A Lee

  • The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment

    Katie F. Daughenbaugh;Chris S. Fraser;John W.B. Hershey;Michele E. Hardy

  • Protein synthesis and protein phosphorylation during heat stress, recovery, and adaptation.

    Roger E Duncan;John W. B. Hershey

  • Individual overexpression of five subunits of human translation initiation factor eIF3 promotes malignant transformation of immortal fibroblast cells.

    Lili Zhang;Xiaoyu Pan;John W.B. Hershey

  • 2 The Pathway and Mechanism of Initiation of Protein Synthesis

    John W. B. Hershey;William C. Merrick

Frequent Co-Authors

Nahum Sonenberg
Nahum Sonenberg McGill University
Michael B. Mathews
Michael B. Mathews Rutgers, The State University of New Jersey
William C. Merrick
William C. Merrick Case Western Reserve University
Robert R. Traut
Robert R. Traut University of California, Davis
Vinay K. Pathak
Vinay K. Pathak National Institutes of Health
Randal J. Kaufman
Randal J. Kaufman Sanford Burnham Prebys Medical Discovery Institute
Marianne Grunberg-Manago
Marianne Grunberg-Manago Centre national de la recherche scientifique, CNRS
Jennifer A. Doudna
Jennifer A. Doudna University of California, Berkeley
Laurence Meyer
Laurence Meyer University of Utah
Alan G. Hinnebusch
Alan G. Hinnebusch National Institutes of Health

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