Thomas E. Dever

Research.com Recognitions

• 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

  Michael J. Gale;Marcus J. Korth;Norina M. Tang;Seng Lai Tan

  1072
  Citations

• Gene-Specific Regulation by General Translation Factors

  Thomas E. Dever

  957
  Citations

• Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

  Thomas E. Dever;Lan Feng;Ronald C. Wek;A.Mark Cigan

  955
  Citations

• Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F.

  Florence Rozen;Isaac Edery;Karen Meerovitch;Thomas E. Dever

  841
  Citations

• GTP-binding domain: three consensus sequence elements with distinct spacing

  Thomas E. Dever;Manuel J. Glynias;William C. Merrick

  797
  Citations

• The joining of ribosomal subunits in eukaryotes requires eIF5B

  Tatyana V. Pestova;Ivan B. Lomakin;Joon H. Lee;Sang Ki Choi

  548
  Citations

• Biochemical mechanisms for translational regulation in synaptic plasticity

  Eric Klann;Thomas E. Dever

  518
  Citations

• Hypusine-containing protein eIF5A promotes translation elongation

  Preeti Saini;Daniel E. Eyler;Rachel Green;Thomas E. Dever

  507
  Citations

• The Elongation, Termination, and Recycling Phases of Translation in Eukaryotes

  Thomas E. Dever;Rachel Green

  504
  Citations

• eIF5A promotes translation of polyproline motifs.

  Erik Gutierrez;Byung-Sik Shin;Christopher J. Woolstenhulme;Joo-Ran Kim

  483
  Citations

• Tight Binding of the Phosphorylated α Subunit of Initiation Factor 2 (eIF2α) to the Regulatory Subunits of Guanine Nucleotide Exchange Factor eIF2B Is Required for Inhibition of Translation Initiation

  Thanuja Krishnamoorthy;Graham D. Pavitt;Fan Zhang;Thomas E. Dever

  463
  Citations

• Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

  Arvin C. Dar;Thomas E. Dever;Frank Sicheri;Frank Sicheri

  459
  Citations

• Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

  Madhusudan Dey;Chune Cao;Arvin C. Dar;Arvin C. Dar;Tomohiko Tamura

  439
  Citations

• Eukaryotic translation initiation factors and regulators

  Nahum Sonenberg;Thomas E Dever

  436
  Citations

• Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

  Kenneth P.K. Lee;Madhusudan Dey;Dante Neculai;Chune Cao

  422
  Citations

• eIF5A Functions Globally in Translation Elongation and Termination

  Anthony P. Schuller;Colin Chih Chien Wu;Thomas E. Dever;Allen R. Buskirk

  409
  Citations

• Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation.

  Kai U. Frerichs;Carolyn B. Smith;Michael Brenner;Donald J. DeGracia

  360
  Citations

• X-ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding

  A. Roll-Mecak;C. Cao;T.E. Dever;S.K. Burley

  291
  Citations

• Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast.

  T. E. Dever;Jane-Jane Chen;G. N. Barber;A. M. Cigan

  265
  Citations

• Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR by Vaccinia Virus E3: Role of Complex Formation and the E3 N-Terminal Domain

  Patrick R. Romano;Fan Zhang;Seng Lai Tan;Minerva T. Garcia-Barrio

  263
  Citations