World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
77
Citations
24925
World Ranking
1101
National Ranking
37

Frank Sicheri publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Frank Sicheri sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 212 publications — 62nd percentile

62% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Frank Sicheri D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Frank Sicheri sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 77 D-Index — 65th percentile

65% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Research.com Recognitions

  • 2011 - Fellow of the Royal Society of Canada Academy of Science

Overview

Frank Sicheri is affiliated with the Lunenfeld-Tanenbaum Research Institute in Canada. Their research activity spans several key areas within biochemistry, genetics, molecular biology, and medicine, producing a substantial volume of publications primarily focused on molecular biology and oncology.

The scientist has contributed extensively to the following main fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these areas, their work delves into various subfields, including:

  • Molecular Biology
  • Oncology
  • Cell Biology
  • Infectious Diseases
  • Materials Chemistry

The primary topics Frank Sicheri's research encompasses are:

  • Ubiquitin and proteasome pathways
  • Peptidase Inhibition and Analysis
  • Protein Degradation and Inhibitors
  • Microtubule and mitosis dynamics
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • DNA Repair Mechanisms

Frequent collaborators include:

  • Stephen Orlicky (14 publications)
  • Igor Kurinov (12 publications)
  • Derek F. Ceccarelli (10 publications)
  • Daniel Y.L. Mao (9 publications)
  • Pierre Maisonneuve (8 publications)

Frank Sicheri often publishes in the following scientific venues:

  • bioRxiv (Cold Spring Harbor Laboratory) - 8 publications
  • Nature Communications - 6 publications
  • Journal of Medicinal Chemistry - 5 publications
  • Structure - 3 publications
  • ACS Chemical Biology - 2 publications

Selected recent publications are as follows:

  • Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients, 2020, Science Immunology
  • Functional characterization of a PROTAC directed against BRAF mutant V600E, 2020, Nature Chemical Biology
  • Mucosal versus systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306, 2022, Journal of Medicinal Chemistry
  • Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ, 2022, Journal of Medicinal Chemistry

Among their recognitions, Frank Sicheri was named a Fellow of the Royal Society of Canada in 2011 by the Academy of Science.

Best Publications

  • Crystal structure of the Src family tyrosine kinase Hck

    Frank Sicheri;Ismail Moarefi;Ismail Moarefi;John Kuriyan;John Kuriyan

  • Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

    Piers Nash;Xiaojing Tang;Stephen Orlicky;Qinghua Chen

  • Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.

    Baweleta Isho;Kento T. Abe;Kento T. Abe;Michelle Zuo;Alainna J. Jamal;Alainna J. Jamal

  • Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

    I Moarefi;M LaFevre-Bernt;F Sicheri;M Huse

  • 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

    Amélie Fradet-Turcotte;Marella D. Canny;Cristina Escribano-Díaz;Alexandre Orthwein

  • Bone recognition mechanism of porcine osteocalcin from crystal structure.

    Quyen Q. Hoang;Frank Sicheri;Frank Sicheri;Andrew J. Howard;Daniel S. C. Yang

  • Structural Basis for Phosphodependent Substrate Selection and Orientation by the SCFCdc4 Ubiquitin Ligase

    Stephen Orlicky;Xiaojing Tang;Andrew Willems;Mike Tyers;Mike Tyers

  • Crystal Structure of Hck in Complex with a Src Family–Selective Tyrosine Kinase Inhibitor

    Thomas Schindler;Frank Sicheri;Alexander Pico;Aviv Gazit

  • A dimerization-dependent mechanism drives RAF catalytic activation

    Thanashan Rajakulendran;Malha Sahmi;Martin Lefrançois;Frank Sicheri

  • Ice-binding structure and mechanism of an antifreeze protein from winter flounder

    F. Sicheri;D. S. C. Yang;D. S. C. Yang

  • Structures of Src-family tyrosine kinases.

    Frank Sicheri;John Kuriyan

  • A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

    Marilyn Goudreault;Lisa M. D'Ambrosio;Lisa M. D'Ambrosio;Michelle J. Kean;Michelle J. Kean;Michael J. Mullin

  • Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions

    Amber L. Couzens;James D. R. Knight;Michelle J. Kean;Michelle J. Kean;Guoci Teo

  • Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

    Arvin C. Dar;Thomas E. Dever;Frank Sicheri;Frank Sicheri

  • Structural Basis for Autoinhibition of the EphB2 Receptor Tyrosine Kinase by the Unphosphorylated Juxtamembrane Region

    Leanne E. Wybenga-Groot;Leanne E. Wybenga-Groot;Berivan Baskin;Siew Hwa Ong;Jiefei Tong

  • Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

    Madhusudan Dey;Chune Cao;Arvin C. Dar;Arvin C. Dar;Tomohiko Tamura

  • Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

    Kenneth P.K. Lee;Madhusudan Dey;Dante Neculai;Chune Cao

  • Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

    Shinichiro Nakada;Ikue Tai;Stephanie Panier;Stephanie Panier;Abdallah Al-Hakim

  • Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor.

    Tanja Mittag;Stephen Orlicky;Wing-Yiu Choy;Xiaojing Tang

  • Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain

    Abiodun A. Ogunjimi;Douglas J. Briant;Nadia Pece-Barbara;Christine Le Roy

Frequent Co-Authors

Mike Tyers
Mike Tyers University of Montreal
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Daniel Durocher
Daniel Durocher Lunenfeld-Tanenbaum Research Institute
Sachdev S. Sidhu
Sachdev S. Sidhu University of Waterloo
Tony Pawson
Tony Pawson University of Toronto
Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Julie D. Forman-Kay
Julie D. Forman-Kay University of Toronto
John Kuriyan
John Kuriyan Vanderbilt University
Thomas E. Dever
Thomas E. Dever National Institutes of Health
Alain Fischer
Alain Fischer Collège de France

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