World's Best Scientists 2026 revealed!
Sachdev S. Sidhu

Sachdev S. Sidhu

D-Index & Metrics

Molecular Biology

D-Index
93
Citations
31850
World Ranking
677
National Ranking
18

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors

Overview

Sachdev S. Sidhu is affiliated with the University of Waterloo in Canada. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant work in Molecular Biology, Radiology, Nuclear Medicine and Imaging, Infectious Diseases, Oncology, and Immunology.

The scholar has contributed to several main research topics, including:

  • Monoclonal and Polyclonal Antibodies Research
  • Ubiquitin and proteasome pathways
  • SARS-CoV-2 and COVID-19 Research
  • Glycosylation and Glycoproteins Research
  • CAR-T cell therapy research
  • Cell Adhesion Molecules Research
  • Autophagy in Disease and Therapy

Sidhu's frequent co-authors include Jarrett Adams, Shane Miersch, Levi L. Blazer, Lia Cardarelli, and Joan Teyra.

Prominent venues where Sidhu has published multiple works are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Molecular Biology
  • Protein Science
  • ACS Chemical Biology
  • UNC Libraries

Key recent papers authored or co-authored by Sidhu cover a range of topics and were published in prominent journals:

  • Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2, 2020, Cell Host & Microbe
  • SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma, 2021, Science Translational Medicine
  • Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2, 2021, Communications Biology
  • Lrp1 is a host entry factor for Rift Valley fever virus, 2021, Cell
  • Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism, 2021, eLife

In 2020, Sidhu was recognized as a Fellow of the National Academy of Inventors.

Best Publications

  • High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

    Traver Hart;Megha Chandrashekhar;Michael Aregger;Zachary Steinhart

  • Comprehensive Functional Maps of the Antigen-binding Site of an Anti-ErbB2 Antibody Obtained with Shotgun Scanning Mutagenesis

    Felix F Vajdos;Camellia W Adams;Timothy N Breece;Leonard G Presta

  • Beyond natural antibodies: the power of in vitro display technologies

    Andrew R.M. Bradbury;Sachdev S Sidhu;Stefan Dübel;John Mccafferty

  • Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies

    Kim Newton;Marissa L. Matsumoto;Ingrid E. Wertz;Donald S. Kirkpatrick

  • High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold.

    Chingwei V Lee;Wei-Ching Liang;Mark S Dennis;Charles Eigenbrot

  • Phage display for selection of novel binding peptides.

    Sachdev S. Sidhu;Henry B. Lowman;Brian C. Cunningham;James A. Wells

  • A specificity map for the PDZ domain family.

    Raffi Tonikian;Yingnan Zhang;Stephen L Sazinsky;Bridget Currell

  • Synthetic antibody phage libraries

    Germaine G. Fuh;Sachdev S. Sidhu

  • Visualization of arrestin recruitment by a G-protein-coupled receptor

    Arun K. Shukla;Gerwin H. Westfield;Kunhong Xiao;Rosana I. Reis

  • Anti-vegf antibodies

    Germaine Fuh;Hans-Peter Gerber;Wei-Ching Liang;Frederic A. Fellouse

  • Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2.

    James Brett Case;Paul W Rothlauf;Rita E Chen;Zhuoming Liu

  • SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma

    Joseph H. Choe;Payal B. Watchmaker;Milos S. Simic;Ryan D. Gilbert

  • Binding polypeptides with optimized scaffolds

    Pierre A. Barthelemy;Sachdev S. Sidhu

  • Rapid mapping of protein functional epitopes by combinatorial alanine scanning.

    Gregory A. Weiss;Colin K. Watanabe;Alan Zhong;Audrey Goddard

  • Variable domain library and uses

    Christopher J. Bond;Sachdev Sidhu

  • High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.

    Frederic A. Fellouse;Kaori Esaki;Sara Birtalan;Demetrios Raptis

  • Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition

    Frederic A. Fellouse;Christian Wiesmann;Sachdev S. Sidhu

  • Phage display in pharmaceutical biotechnology

    Sachdev S Sidhu

  • Binding polypeptides with restricted diversity sequences

    Sara C. Birtalan;Frederic A. Fellouse;Sachdev S. Sidhu

  • Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma

    M.A. Qazi;P. Vora;C. Venugopal;S.S. Sidhu

Frequent Co-Authors

Jason Moffat
Jason Moffat University of Toronto
Frank Sicheri
Frank Sicheri Lunenfeld-Tanenbaum Research Institute
Christian Wiesmann
Christian Wiesmann Novartis (Switzerland)
Stephane Angers
Stephane Angers University of Toronto
Shohei Koide
Shohei Koide New York University
Anthony A. Kossiakoff
Anthony A. Kossiakoff University of Chicago
Philip M. Kim
Philip M. Kim University of Toronto
Germaine Fuh
Germaine Fuh Genentech
Gary D. Bader
Gary D. Bader University of Toronto
Jinrong Min
Jinrong Min Structural Genomics Consortium

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

There are many flexible options for advancing your education in related fields to molecular biology. If you’re seeking quality and trust, consider non profit universities. These institutions usually have rigorous accreditation, experienced faculty, and often provide better financial support.

For military members or veterans, choosing from online military friendly colleges ensures a supportive learning environment. Such programs often include flexible schedules and specialized support services.

If you’re looking to expand into healthcare or social impact, msw online programs (Master of Social Work) can be a strong choice. These degrees empower graduates to support communities and can be completed remotely.

Additionally, for those eager to speed up their education, exploring accelerated masters in psychology is an option. These programs allow you to obtain credentials quickly and enter growing fields such as counseling or behavioral research.

Best Scientists Citing Sachdev S. Sidhu

Trending Scientists

Recently Published Articles