Anthony A. Kossiakoff

Research.com Recognitions

• 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

  AM de Vos;M Ultsch;AA Kossiakoff

  3402
  Citations

• Visualization of arrestin recruitment by a G-protein-coupled receptor

  Arun K. Shukla;Gerwin H. Westfield;Kunhong Xiao;Rosana I. Reis

  526
  Citations

• Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

  Arun K. Shukla;Aashish Manglik;Andrew C Kruse;Kunhong Xiao

  477
  Citations

• The X-ray structure of a growth hormone–prolactin receptor complex

  W Somers;M Ultsch;A M De Vos;A A Kossiakoff

  477
  Citations

• High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.

  Frederic A. Fellouse;Kaori Esaki;Sara Birtalan;Demetrios Raptis

  436
  Citations

• Direct determination of the protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin

  Anthony A. Kossiakoff;Steven A. Spencer

  361
  Citations

• X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.

  Charles Eigenbrot;Michael Randal;Leonard Presta;Paul Carter

  354
  Citations

• Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution.

  Lars Abrahmsen;Jeffrey Tom;John Burnier;Karen A. Butcher

  354
  Citations

• Tertiary structure is a principal determinant to protein deamidation.

  AA Kossiakoff

  312
  Citations

• Crystal structure of full-length KcsA in its closed conformation

  Serdar Uysal;Valeria Vásquez;Valentina Tereshko;Kaori Esaki

  279
  Citations

• X-ray Structure of Snow Flea Antifreeze Protein Determined by Racemic Crystallization of Synthetic Protein Enantiomers

  Brad L. Pentelute;Zachary P. Gates;Valentina Tereshko;Jennifer L. Dashnau

  267
  Citations

• Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain

  Qufei Li;Sherry Wanderling;Marcin Paduch;David Medovoy

  262
  Citations

• Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

  Yanyong Kang;Oleg Kuybeda;Parker W. de Waal;Somnath Mukherjee

  259
  Citations

• Structure of bovine trypsinogen at 1.9 A resolution.

  Anthony A. Kossiakoff;John L. Chambers;Lois M. Kay;Robert M. Stroud

  253
  Citations

• The crystallographically determined structures of atypical strained disulfides engineered into subtilisin.

  B A Katz;A Kossiakoff

  250
  Citations

• The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation.

  R Bott;M Ultsch;A Kossiakoff;T Graycar

  247
  Citations

• Protein dynamics investigated by the neutron diffraction–hydrogen exchange technique

  A A Kossiakoff

  239
  Citations

• Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.

  Axel J. Scheidig;Thomas R. Hynes;Laura A. Pelletier;James A. Wells

  193
  Citations

• X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor.

  Thomas R. Hynes;Michael Randal;Laura A. Kennedy;Charles Eigenbrot

  187
  Citations

• The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s)

  B Gopal;Lalima L Madan;Stephen F Betz;Anthony A Kossiakoff

  186
  Citations