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Chemistry

D-Index
54
Citations
18360
World Ranking
12440
National Ranking
3315

Overview

Paul Langan is affiliated with Oak Ridge National Laboratory in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a particular emphasis on molecular biology and biomedical engineering.

The scientist's work focuses on multiple specialized topics including:

  • SARS-CoV-2 and COVID-19 Research
  • Computational Drug Discovery Methods
  • RNA and protein synthesis mechanisms
  • Advanced Cellulose Research Studies
  • Biofuel production and bioconversion
  • Polysaccharides and Plant Cell Walls
  • Machine Learning in Healthcare

Paul Langan has contributed to several peer-reviewed papers in notable publication venues. Recent publications include:

  • Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography, 2020, Nature Communications
  • Untangling the threads of cellulose mercerization, 2022, Nature Communications
  • Morphological changes in the cellulose and lignin components of biomass occur at different stages of steam pretreatment, 2021, HAL (Le Centre pour la Communication Scientifique Directe)
  • Trustworthy Data and AI Environments for Clinical Prediction: Application to Crisis-Risk in People With Depression, 2023, IEEE Journal of Biomedical and Health Informatics
  • Capturing the Catalytic Proton of Dihydrofolate Reductase: Implications for General Acid-Base Catalysis, 2021, ACS Catalysis

Frequent co-authors collaborating with Paul Langan include:

  • Hugh O'Neill
  • Andrey Kovalevsky
  • Daniel W. Kneller
  • G.N. Phillips
  • R. Jedrzejczak

The scientist's publications have appeared primarily in the following venues:

  • Nature Communications
  • IEEE Journal of Biomedical and Health Informatics
  • Research Square (Research Square)
  • ACS Catalysis
  • HAL (Le Centre pour la Communication Scientifique Directe)

Best Publications

  • Lignin valorization: improving lignin processing in the biorefinery.

    Arthur J. Ragauskas;Gregg T. Beckham;Mary J. Biddy;Richard Chandra

  • Crystal Structure and Hydrogen-Bonding System in Cellulose Iβ from Synchrotron X-ray and Neutron Fiber Diffraction

    Yoshiharu Nishiyama;Paul Langan;Henri Chanzy

  • X-ray structure of mercerized cellulose II at 1 Å resolution

    Paul Langan;Yoshiharu Nishiyama;Henri Chanzy

  • Structural plasticity of SARS-CoV-2 3CL M pro active site cavity revealed by room temperature X-ray crystallography.

    Daniel W. Kneller;Gwyndalyn Phillips;Hugh M. O’Neill;Robert Jedrzejczak

  • A REVISED STRUCTURE AND HYDROGEN-BONDING SYSTEM IN CELLULOSE II FROM A NEUTRON FIBER DIFFRACTION ANALYSIS

    P. Langan;Y. Nishiyama;H. Chanzy

  • Restructuring the crystalline cellulose hydrogen bond network enhances its depolymerization rate

    Shishir P. S. Chundawat;Giovanni Bellesia;Nirmal Uppugundla;Leonardo da Costa Sousa

  • Cellulose IIII Crystal Structure and Hydrogen Bonding by Synchrotron X-ray and Neutron Fiber Diffraction

    Masahisa Wada;Henri Chanzy;Yoshiharu Nishiyama;Paul Langan

  • Joint X-ray and neutron refinement with phenix.refine

    Pavel V. Afonine;Marat Mustyakimov;Ralf W. Grosse-Kunstleve;Nigel W. Moriarty

  • Neutron crystallography, molecular dynamics, and quantum mechanics studies of the nature of hydrogen bonding in cellulose Ibeta.

    Yoshiharu Nishiyama;Glenn P. Johnson;Alfred D. French;V. Trevor Forsyth

  • Periodic disorder along ramie cellulose microfibrils.

    Yoshiharu Nishiyama;Ung-Jin Kim;Dae-Young Kim;Kyoko S. Katsumata

  • Common processes drive the thermochemical pretreatment of lignocellulosic biomass

    Paul Langan;Paul Langan;Loukas Petridis;Loukas Petridis;Hugh M. O'Neill;Sai Venkatesh Pingali

  • Insights into Hydrogen Bonding and Stacking Interactions in Cellulose

    R. Parthasarathi;G. Bellesia;S. P. S. Chundawat;S. P. S. Chundawat;B. E. Dale;B. E. Dale

  • Metal ion roles and the movement of hydrogen during reaction catalyzed by D-xylose isomerase: a joint x-ray and neutron diffraction study.

    Andrey Y. Kovalevsky;Leif Hanson;S. Zoe Fisher;Marat Mustyakimov

  • Neutron crystallography: opportunities, challenges, and limitations

    Matthew P Blakeley;Paul Langan;Paul Langan;Nobuo Niimura;Alberto Podjarny

  • Effect of lignin content on changes occurring in poplar cellulose ultrastructure during dilute acid pretreatment

    Qining Sun;Marcus Foston;Xianzhi Meng;Daisuke Sawada

  • Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules

    Paul D. Adams;Paul D. Adams;Marat Mustyakimov;Pavel V. Afonine;Paul Langan

  • Ionic-liquid induced changes in cellulose structure associated with enhanced biomass hydrolysis.

    Indira P. Samayam;B. Leif Hanson;Paul Langan;Constance A. Schall

  • Synchrotron X-ray structures of cellulose Iβ and regenerated cellulose II at ambient temperature and 100 K

    Paul Langan;Narayanasami Sukumar;Yoshiharu Nishiyama;Henri Chanzy

  • Dynamics of water bound to crystalline cellulose

    Hugh O'Neill;Hugh O'Neill;Sai Venkatesh Pingali;Loukas Petridis;Loukas Petridis;Junhong He

  • Conformational flexibility of soluble cellulose oligomers: chain length and temperature dependence.

    Tongye Shen;Paul Langan;Alfred D. French;Glenn P. Johnson

  • New Insights into Hydrogen Bonding and Stacking Interactions in Cellulose

    Paul Langan

Frequent Co-Authors

Andrey Kovalevsky
Andrey Kovalevsky Oak Ridge National Laboratory
Yoshiharu Nishiyama
Yoshiharu Nishiyama Centre national de la recherche scientifique, CNRS
Jeremy C. Smith
Jeremy C. Smith University of Tennessee at Knoxville
Masahisa Wada
Masahisa Wada Kyoto University
Hugh O'Neill
Hugh O'Neill Oak Ridge National Laboratory
Brian H. Davison
Brian H. Davison Oak Ridge National Laboratory
Paul D. Adams
Paul D. Adams Lawrence Berkeley National Laboratory
Henri Chanzy
Henri Chanzy Joseph Fourier University
Arthur J. Ragauskas
Arthur J. Ragauskas University of Tennessee at Knoxville
David A. Keen
David A. Keen Rutherford Appleton Laboratory

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