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Molecular Biology

D-Index
54
Citations
9950
World Ranking
2327
National Ranking
1149

Overview

Akiko Koide is affiliated with NYU Langone Health in the United States. Their research spans multiple fields with a particular focus on Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader areas, major subfields of study include Molecular Biology, Radiology, Nuclear Medicine and Imaging, Infectious Diseases, Oncology, and Immunology.

The scientist has contributed extensively to topics such as Monoclonal and Polyclonal Antibodies Research, SARS-CoV-2 and COVID-19 Research, CAR-T cell therapy research, COVID-19 Clinical Research Studies, Glycosylation and Glycoproteins Research, Protein Kinase Regulation and GTPase Signaling, and Receptor Mechanisms and Signaling.

Notable recent papers authored by Akiko Koide include:

  • SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling, 2020, The Journal of Experimental Medicine
  • Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome, 2021, Nature Microbiology
  • Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis, 2021, Nature Communications
  • Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies, 2020, Proceedings of the National Academy of Sciences
  • Selective and noncovalent targeting of RAS mutants for inhibition and degradation, 2021, Nature Communications

Frequent co-authors in their research collaborations include Shohei Koide, Takamitsu Hattori, Kai Wen Teng, Alexis D. Corrado, and John P. O'Bryan.

The scientist's work has been published recurrently in several notable venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Proceedings of the National Academy of Sciences, Cancer Research, and Biophysical Journal.

Best Publications

  • The fibronectin type III domain as a scaffold for novel binding proteins

    Akiko Koide;Charles W Bailey;Xiaolin Huang;Shohei Koide

  • Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

    Arun K. Shukla;Aashish Manglik;Andrew C Kruse;Kunhong Xiao

  • High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.

    Frederic A. Fellouse;Kaori Esaki;Sara Birtalan;Demetrios Raptis

  • Molecular Mechanism of Thioflavin-T Binding to the Surface of β-Rich Peptide Self-Assemblies

    Matthew Biancalana;Koki Makabe;Akiko Koide;Shohei Koide

  • Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold.

    Akiko Koide;John Wojcik;Ryan N. Gilbreth;Robert J. Hoey

  • High-affinity single-domain binding proteins with a binary-code interface

    Akiko Koide;Ryan N. Gilbreth;Kaori Esaki;Valentina Tereshko

  • Inhibition of RAS function through targeting an allosteric regulatory site

    Russell Spencer-Smith;Akiko Koide;Yong Zhou;Raphael R Eguchi

  • Monobodies: antibody mimics based on the scaffold of the fibronectin type III domain.

    Akiko Koide;Shohei Koide

  • CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies.

    Helena Persson;Wei Ye;Amy Wernimont;Jarrett J. Adams

  • Probing protein conformational changes in living cells by using designer binding proteins: Application to the estrogen receptor

    Akiko Koide;Stacy Abbatiello;Lisa Rothgery;Shohei Koide

  • A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.

    John Wojcik;Oliver Hantschel;Florian Grebien;Ines Kaupe

  • SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling.

    Carmine Fedele;Shuai Li;Kai Wen Teng;Connor J.R. Foster

  • Structures of a Na+-coupled, substrate-bound MATE multidrug transporter

    Min Lu;Jindrich Symersky;Martha Radchenko;Akiko Koide

  • Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

    Florian Grebien;Oliver Hantschel;John Wojcik;Ines Kaupe

  • Synthetic antibodies for specific recognition and crystallization of structured RNA

    Jing-Dong Ye;Valentina Tereshko;John K. Frederiksen;Akiko Koide

  • Exploring the potential of the monobody scaffold: effects of loop elongation on the stability of a fibronectin type III domain.

    Vincent Batori;Akiko Koide;Shohei Koide

  • Identification of a second oligopeptide transport system in Bacillus subtilis and determination of its role in sporulation

    Akiko Koide;James A. Hoch

  • Engineered Fibronectin Type III Domain with a RGDWXE Sequence Binds with Enhanced Affinity and Specificity to Human αvβ3 Integrin

    Julie Richards;Michelle Miller;Johanna Abend;Akiko Koide

  • Stabilization of a Fibronectin Type III Domain by the Removal of Unfavorable Electrostatic Interactions on the Protein Surface

    Akiko Koide;Michael R. Jordan;Scott R. Horner;Vincent Batori

  • Architecture of the fungal nuclear pore inner ring complex

    Tobias Stuwe;Christopher J. Bley;Karsten Thierbach;Stefan Petrovic

Frequent Co-Authors

Shohei Koide
Shohei Koide New York University
Anthony A. Kossiakoff
Anthony A. Kossiakoff University of Chicago
Sachdev S. Sidhu
Sachdev S. Sidhu University of Waterloo
Tony Pawson
Tony Pawson University of Toronto
Stephen Dewhurst
Stephen Dewhurst University of Rochester
Valentina Tereshko
Valentina Tereshko University of Chicago
Brian D. Strahl
Brian D. Strahl University of North Carolina at Chapel Hill
Christopher Miller
Christopher Miller Brandeis University
Andreas G. Ladurner
Andreas G. Ladurner Ludwig-Maximilians-Universität München
Sangram S. Sisodia
Sangram S. Sisodia University of Chicago

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