World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11419
World Ranking
15553
National Ranking
1094

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Andreas G. Ladurner mainly investigates Biochemistry, Chromatin, Cell biology, Histone and Enzyme. His study on DNA damage, NAD+ kinase, Plasma protein binding and DNA supercoil is often connected to DNA clamp as part of broader study in Biochemistry. The Chromatin study combines topics in areas such as Poly ADP ribose polymerase and Macro domain.

His work carried out in the field of Cell biology brings together such families of science as Genetics, Histone code, Transcription Factor TFIID, HMG-box and Histone H2A. His work deals with themes such as Biomarker, Lung cancer, Epigenetics and Immunology, which intersect with Histone. Andreas G. Ladurner works mostly in the field of Enzyme, limiting it down to concerns involving Peptide sequence and, occasionally, PARG, DNA repair and Mutation.

His most cited work include:

  • Structure and function of a human TAFII250 double bromodomain module. (722 citations)
  • The macro domain is an ADP-ribose binding module (385 citations)
  • The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. (334 citations)

What are the main themes of his work throughout his whole career to date?

Andreas G. Ladurner focuses on Cell biology, Chromatin, Histone, Biochemistry and Genetics. His Cell biology research incorporates themes from DNA, DNA damage, PARP1, Nucleosome and NAD+ kinase. His Nucleosome research focuses on Molecular biology and how it relates to Transcription factor II D, TAF1 and RNA polymerase II.

His study in Chromatin is interdisciplinary in nature, drawing from both Regulation of gene expression, CHD1L and Poly ADP ribose polymerase. The study incorporates disciplines such as Gene expression, Acetylation, Epigenetics and DNA-binding protein in addition to Histone. His Biochemistry study frequently draws connections to other fields, such as Biophysics.

He most often published in these fields:

  • Cell biology (68.52%)
  • Chromatin (56.48%)
  • Histone (43.52%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (68.52%)
  • Chromatin (56.48%)
  • PARP1 (24.07%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Chromatin, PARP1, Histone and DNA damage. Andreas G. Ladurner studied Cell biology and DNA repair that intersect with NAD+ kinase and Poly ADP ribose polymerase. His Poly ADP ribose polymerase study results in a more complete grasp of Biochemistry.

Andreas G. Ladurner interconnects RNA polymerase II and Active site in the investigation of issues within Chromatin. His studies deal with areas such as Pharmacology toxicology, Schizosaccharomyces pombe and Chaperone as well as Histone. His biological study spans a wide range of topics, including Heterochromatin, Serine, DNA-binding protein and Gene isoform.

Between 2017 and 2021, his most popular works were:

  • MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms (25 citations)
  • MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms (25 citations)
  • The taming of PARP1 and its impact on NAD+ metabolism (11 citations)

Best Publications

  • Structure and Function of a Human TAFII250 Double Bromodomain Module

    Raymond H. Jacobson;Andreas G. Ladurner;David S. King;Robert Tjian

  • The macro domain is an ADP-ribose binding module

    Georgios I Karras;Georg Kustatscher;Heeran R Buhecha;Mark D Allen

  • The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

    Soojin Ryu;Sharleen Zhou;Andreas G. Ladurner;Robert Tjian

  • A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.

    Gyula Timinszky;Susanne Till;Paul O Hassa;Michael Hothorn

  • Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler.

    Aaron J. Gottschalk;Gyula Timinszky;Stephanie E. Kong;Jingji Jin

  • A unified phylogeny-based nomenclature for histone variants

    Paul B Talbert;Kami Ahmad;Geneviève Almouzni;Juan Ausió

  • A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

    Gytis Jankevicius;Markus Hassler;Barbara Golia;Vladimir Rybin

  • Splicing regulates NAD metabolite binding to histone macroH2A.

    Georg Kustatscher;Michael Hothorn;Céline Pugieux;Klaus Scheffzek

  • Deficiency of terminal ADP‐ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

    Reza Sharifi;Rosa Morra;C Denise Appel;Michael Tallis

  • Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase.

    Michael Hothorn;Heinz Neumann;Esther D. Lenherr;Mark Wehner

  • The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks

    Ammar A E Ali;Gyula Timinszky;Gyula Timinszky;Raquel Arribas-Bosacoma;Marek Kozlowski;Marek Kozlowski

  • A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain.

    Susanne Till;Erwan Lejeune;Rolf Thermann;Miriam Bortfeld

  • Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries.

    Andreas G. Ladurner;Carla Inouye;Rajan Jain;Robert Tjian

  • ADP-ribosyltransferases, an update on function and nomenclature

    Bernhard Lüscher;Ivan Ahel;Matthias Altmeyer;Alan Ashworth

  • Structures of Drosophila Cryptochrome and Mouse Cryptochrome1 Provide Insight into Circadian Function

    Anna Czarna;Alex Berndt;Hari Raj Singh;Astrid Grudziecki

  • Histone macroH2A isoforms predict the risk of lung cancer recurrence

    Judith C. Sporn;Georg Kustatscher;Torsten Hothorn;Manuel Collado

  • Structural basis of histone H2A–H2B recognition by the essential chaperone FACT

    Maria Hondele;Tobias Stuwe;Markus Hassler;Felix Halbach

  • Three-dimensional structure of the human TFIID-IIA-IIB complex.

    Frank Andel;Andreas G. Ladurner;Carla Inouye;Robert Tjian

  • The Metabolic Impact on Histone Acetylation and Transcription in Ageing

    Shahaf Peleg;Christian Feller;Andreas G. Ladurner;Axel Imhof

  • The FACT Spt16 “peptidase” domain is a histone H3–H4 binding module

    Tobias Stuwe;Michael Hothorn;Erwan Lejeune;Vladimir Rybin

Frequent Co-Authors

Michael Hothorn
Michael Hothorn University of Geneva
Alan R. Fersht
Alan R. Fersht University of Cambridge
Axel Imhof
Axel Imhof Ludwig-Maximilians-Universität München
Robert Tjian
Robert Tjian University of California, Berkeley
Klaus Scheffzek
Klaus Scheffzek Innsbruck Medical University
Vladimir Rybin
Vladimir Rybin European Molecular Biology Laboratory
Susan M. Gasser
Susan M. Gasser Friedrich Miescher Institute
Tobias Straub
Tobias Straub Ludwig-Maximilians-Universität München
Laurence H. Pearl
Laurence H. Pearl University of Sussex
Ivan Ahel
Ivan Ahel University of Oxford

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