What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Cell biology, Chromatin, Biochemistry, Regulation of gene expression and Poly ADP ribose polymerase.
His research in Cell biology intersects with topics in Chromatin remodeling and Transcription.
The concepts of his Transcription study are interwoven with issues in Molecular biology, Estrogen receptor alpha and Estrogen receptor binding.
His research integrates issues of Enhancer, Histone and DNA methylation in his study of Chromatin.
The various areas that W. Lee Kraus examines in his Regulation of gene expression study include Gene expression and Transcriptional regulation.
W. Lee Kraus has researched Poly ADP ribose polymerase in several fields, including Chemical biology, Cell nucleus, Signal transduction and DNA repair.
His most cited work include:
- New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. (705 citations)
- Poly(ADP-ribosyl)ation by PARP-1: `PAR-laying' NAD+ into a nuclear signal (650 citations)
- The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets (595 citations)
What are the main themes of his work throughout his whole career to date?
W. Lee Kraus mainly investigates Cell biology, Chromatin, Regulation of gene expression, Transcription and Genetics.
His Cell biology research integrates issues from Molecular biology, Transcription coregulator, Estrogen receptor, Estrogen receptor alpha and NAD+ kinase.
While the research belongs to areas of Estrogen receptor alpha, W. Lee Kraus spends his time largely on the problem of Transcriptome, intersecting his research to questions surrounding Non-coding RNA.
His studies deal with areas such as Histone and Poly ADP ribose polymerase as well as Chromatin.
His work deals with themes such as RNA, Nuclear receptor and Gene expression, which intersect with Regulation of gene expression.
His Genetics study which covers Computational biology that intersects with Genomics.
He most often published in these fields:
- Cell biology (42.65%)
- Chromatin (27.21%)
- Regulation of gene expression (27.21%)
What were the highlights of his more recent work (between 2016-2021)?
- Cell biology (42.65%)
- Enhancer (15.44%)
- Gene expression (16.18%)
In recent papers he was focusing on the following fields of study:
W. Lee Kraus spends much of his time researching Cell biology, Enhancer, Gene expression, Transcription and Regulation of gene expression.
His biological study spans a wide range of topics, including Transcriptome, Transcriptional regulation, Estrogen receptor, Estrogen receptor alpha and NAD+ kinase.
He has included themes like Cancer research, Ovarian cancer and Signal transduction in his Gene expression study.
His Transcription study combines topics in areas such as PARP inhibitor and DNA repair.
He combines subjects such as RNA, Nuclear receptor and Messenger RNA with his study of Regulation of gene expression.
His Histone course of study focuses on Chromatin and Proteomics.
Between 2016 and 2021, his most popular works were:
- PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes (265 citations)
- Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. (72 citations)
- PARP Inhibitors for Cancer Therapy (59 citations)
In his most recent research, the most cited papers focused on:
Transcription, Enhancer, Transcription factor, Cell biology and Regulation of gene expression are his primary areas of study.
W. Lee Kraus interconnects Cancer cell, Cancer research and DNA repair in the investigation of issues within Transcription.
His DNA repair research includes themes of Chromatin, Computational biology and DNA damage.
His Transcription factor research is classified as research in Genetics.
His studies deal with areas such as Nuclear receptor coactivator 3, Estrogen receptor, Bromodomain and Nuclear receptor coactivator 2 as well as Cell biology.
His Regulation of gene expression study incorporates themes from Evolutionary biology, Messenger RNA, RNA and Locus.
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