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Medicine

D-Index
80
Citations
17306
World Ranking
17317
National Ranking
8676

Overview

Alfredo A. Molinolo is affiliated with the University of California, San Diego, United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a significant focus on subfields such as Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Immunology, and Cancer Research.

The scientist's work addresses a variety of topics, including:

  • Cancer Immunotherapy and Biomarkers
  • Ubiquitin and proteasome pathways
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Estrogen and related hormone effects
  • Lung Cancer Treatments and Mutations
  • Immune cells in cancer

Alfredo A. Molinolo has contributed to multiple research studies published in prominent venues. Some recent publications include:

  • A proteogenomic portrait of lung squamous cell carcinoma, 2021, Cell
  • Pembrolizumab plus cetuximab in patients with recurrent or metastatic head and neck squamous cell carcinoma: an open-label, multi-arm, non-randomised, multicentre, phase 2 trial, 2021, The Lancet Oncology
  • Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC, 2022, Nature Communications
  • Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell Carcinomas, 2020, Molecular Cancer Therapeutics
  • HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers, 2020, Oncogene

The scientist frequently publishes in venues such as:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Biopreservation and Biobanking
  • Clinical Cancer Research

Collaboration has been a notable aspect of their research career. Frequent co-authors include:

  • J. Silvio Gutkind
  • Zhiyong Wang
  • Joseph A. Califano
  • Ezra E.W. Cohen
  • Robert Saddawi-Konefka

Best Publications

  • Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation

    Masako Miura;Yasuo Miura;Hesed M. Padilla‐Nash;Alfredo A. Molinolo

  • Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

    Xiaodong Feng;Xiaodong Feng;Maria Sol Degese;Ramiro Iglesias-Bartolome;Jose P. Vaque

  • Tumor-induced osteomalacia

    William H Chong;Alfredo A Molinolo;Clara C Chen;Michael T Collins

  • Dysregulated molecular networks in head and neck carcinogenesis

    Alfredo A. Molinolo;Panomwat Amornphimoltham;Cristiane H. Squarize;Rogerio M. Castilho

  • Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes

    Silvia Montaner;Akrit Sodhi;Akrit Sodhi;Alfredo Molinolo;Thomas H Bugge

  • A proteogenomic portrait of lung squamous cell carcinoma

    Shankha Satpathy;Karsten Krug;Pierre M. Jean Beltran;Sara R. Savage

  • Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes.

    Ruslan Novosyadlyy;Danielle E. Lann;Archana Vijayakumar;Anne Rowzee;Anne Rowzee

  • Generation and Characterization of B72.3 Second Generation Monoclonal Antibodies Reactive with the Tumor-associated Glycoprotein 72 Antigen

    R Muraro;M Kuroki;D Wunderlich;D J Poole

  • Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation

    Karin List;Roman Szabo;Alfredo Molinolo;Virote Sriuranpong

  • mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

    Ramiro Iglesias-Bartolome;Vyomesh Patel;Ana Cotrim;Kantima Leelahavanichkul

  • Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.

    Alfredo A. Molinolo;Stephen M. Hewitt;Panomwat Amornphimoltham;Somboon Keelawat

  • Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.

    Panomwat Amornphimoltham;Vyomesh Patel;Akrit Sodhi;Nikolaos G. Nikitakis

  • Denosumab Treatment for Fibrous Dysplasia

    Alison M Boyce;William H Chong;Jack Yao;Rachel I Gafni

  • Proteomic analysis of laser-captured paraffin-embedded tissues: A molecular portrait of head and neck cancer progression

    Vyomesh Patel;Brian L. Hood;Alfredo A. Molinolo;Norman H. Lee

  • Transcriptional signature primes human oral mucosa for rapid wound healing.

    Ramiro Iglesias-Bartolome;Akihiko Uchiyama;Alfredo A. Molinolo;Alfredo A. Molinolo;Loreto Abusleme

  • The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies

    Daniel Martin;Martín Carlos Abba;Alfredo A. Molinolo;Lynn Vitale-Cross

  • mTOR as a Molecular Target in HPV-Associated Oral and Cervical Squamous Carcinomas

    Alfredo A Molinolo;Christina A. Marsh;Mohamed El Dinali;Nitin Gangane

  • Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01.

    Panomwat Amornphimoltham;Virote Sriuranpong;Vyomesh Patel;Fernando Jose Benavides

  • The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

    Akrit Sodhi;Akrit Sodhi;Risa Chaisuparat;Jiadi Hu;Amanda K. Ramsdell

  • Positive Surgical Margins in the 10 Most Common Solid Cancers

    Ryan K. Orosco;Viridiana J. Tapia;Joseph A. Califano;Bryan Clary

Frequent Co-Authors

J. Silvio Gutkind
J. Silvio Gutkind University of California, San Diego
Thomas H. Bugge
Thomas H. Bugge National Institutes of Health
Qianming Chen
Qianming Chen Sichuan University
Stephen M. Hewitt
Stephen M. Hewitt National Institutes of Health
Joseph A. Califano
Joseph A. Califano University of California, San Diego
Scott M. Lippman
Scott M. Lippman University of California, San Diego
Ezra E.W. Cohen
Ezra E.W. Cohen University of California, San Diego
Jeffrey Schlom
Jeffrey Schlom National Institutes of Health
Yardena Samuels
Yardena Samuels Weizmann Institute of Science
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health

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