Her main research concerns Mutation, Cancer research, Genetics, Melanoma and P110α. Her Mutation study incorporates themes from Caenorhabditis elegans, Carcinogenesis, Downregulation and upregulation, Kinase activity and PI3K/AKT/mTOR pathway. Her Cancer research research incorporates elements of Gene, Kinase and PTEN.
Her work on Mutant and Cell cycle as part of general Genetics study is frequently linked to Cohesin complex, Chromosome instability and Chromatid, therefore connecting diverse disciplines of science. Her study in Melanoma is interdisciplinary in nature, drawing from both Cancer, Epitope, Immunology, Antigen and Adoptive cell transfer. She has researched Cancer in several fields, including Signal transduction and Bioinformatics.
Her scientific interests lie mostly in Cancer research, Melanoma, Mutation, Cancer and Genetics. Her work deals with themes such as Cell growth, Somatic cell, Mutant, Signal transduction and Tumor suppressor gene, which intersect with Cancer research. Her Melanoma research includes themes of Immunology, Antigen, Metastasis, Neuroblastoma RAS viral oncogene homolog and Nonsense mutation.
Her research investigates the connection with Mutation and areas like P110α which intersect with concerns in Oncogene. Her research integrates issues of Exome sequencing, Exome, Computational biology and Bioinformatics in her study of Cancer. In general Genetics study, her work on PI3K/AKT/mTOR pathway, Germline mutation, Repressor and Regulation of gene expression often relates to the realm of Synonymous substitution, thereby connecting several areas of interest.
Yardena Samuels mostly deals with Cancer research, Melanoma, Immune system, Neuroblastoma RAS viral oncogene homolog and Human leukocyte antigen. Yardena Samuels has included themes like Cell, Trametinib, MAPK/ERK pathway, Nonsense mutation and Antigen presentation in her Cancer research study. Her research in Melanoma is mostly concerned with Cutaneous melanoma.
Her Neuroblastoma RAS viral oncogene homolog research is within the category of Mutation. She works mostly in the field of Human leukocyte antigen, limiting it down to concerns involving Major histocompatibility complex and, occasionally, Computational biology, Cancer immunology and Adoptive cell transfer. Her work in Cancer addresses subjects such as Protein kinase domain, which are connected to disciplines such as Signal transduction.
Her primary areas of study are Cancer research, Immune system, Melanoma, Antigen presentation and Human leukocyte antigen. A large part of her Cancer research studies is devoted to Melanoma patient. As part of her studies on Immune system, Yardena Samuels often connects relevant subjects like Clonal diversity.
The study incorporates disciplines such as Intracellular parasite, Tumor-infiltrating lymphocytes, Immunotherapy, PSMB8 and Antigen in addition to Antigen presentation. The concepts of her Human leukocyte antigen study are interwoven with issues in Intracellular and Bacteria.
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High frequency of mutations of the PIK3CA gene in human cancers
Yardena Samuels;Zhenghe Wang;Alberto Bardelli;Natalie Silliman.
Genomic Classification of Cutaneous Melanoma
Rehan Akbani;Kadir C. Akdemir;B. Arman Aksoy;Monique Albert.
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
Yardena Samuels;Luis A. Diaz;Oleg Schmidt-Kittler;Jordan M. Cummins.
Cancer Cell (2005)
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
Paul F. Robbins;Yong Chen Lu;Mona El-Gamil;Yong F. Li.
Nature Medicine (2013)
The PIK3CA gene is mutated with high frequency in human breast cancers
Kurtis E. Bachman;Pedram Argani;Yardena Samuels;Natalie Silliman.
Cancer Biology & Therapy (2004)
Oncogenic PI3K and its role in cancer.
Yardena Samuels;Kajsa Ericson.
Current Opinion in Oncology (2006)
The Structure of a Human p110α/p85α Complex Elucidates the Effects of Oncogenic PI3Kα Mutations
Chuan Hsiang Huang;Diana Mandelker;Oleg Schmidt-Kittler;Yardena Samuels;Yardena Samuels.
Colorectal cancer: mutations in a signalling pathway.
D. Williams Parsons;Tian Li Wang;Yardena Samuels;Alberto Bardelli;Alberto Bardelli.
Exome sequencing identifies GRIN2A as frequently mutated in melanoma
Xiaomu Wei;Vijay Walia;Jimmy C Lin;Jamie K Teer.
Nature Genetics (2011)
Oncogenic Mutations of PIK3CA in Human Cancers
Yardena Samuels;Victor E. Velculescu.
Cell Cycle (2004)
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