John D. Wade

Overview

Best Publications

• The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

  Maria Rozakis-Adcock;Ross Fernley;John Wade;Tony Pawson;Tony Pawson

  1309
  Citations

• INSL3/Leydig Insulin-like Peptide Activates the LGR8 Receptor Important in Testis Descent

  Jin Kumagai;Sheau Yu Hsu;Hirotaka Matsumi;Jae-Sook Roh

  459
  Citations

• Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family.

  Ross A.D. Bathgate;Chrishan S. Samuel;Tanya C.D. Burazin;Sharon Layfield

  444
  Citations

• Chemically modified and conjugated antimicrobial peptides against superbugs.

  Wenyi Li;Frances Separovic;Neil M O'Brien-Simpson;John D Wade

  398
  Citations

• Paracrine regulation of mammalian oocyte maturation and male germ cell survival.

  Kazuhiro Kawamura;Jin Kumagai;Satoko Sudo;Sang-Young Chun

  385
  Citations

• Current challenges in peptide-based drug discovery

  Laszlo Otvos;John D. Wade

  378
  Citations

• Amyloid- Peptide (A ) Neurotoxicity Is Modulated by the Rate of Peptide Aggregation: A Dimers and Trimers Correlate with Neurotoxicity

  Lin Wai Hung;Giuseppe D Ciccotosto;Eleni Giannakis;Deborah J Tew

  259
  Citations

• Neurotoxic, Redox-competent Alzheimer's β-Amyloid Is Released from Lipid Membrane by Methionine Oxidation

  Kevin J. Barnham;Giuseppe D. Ciccotosto;Anna K. Tickler;Anna K. Tickler;Feda E. Ali

  245
  Citations

• Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge

  D P Smith;D P Smith;Danielle G Smith;Danielle G Smith;Cyril C Curtain;Cyril C Curtain;Cyril C Curtain;John Frank Boas

  230
  Citations

• Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones.

  Longwen Deng;Cynthia de la Fuente;Peng Fu;Lai Wang

  214
  Citations

• Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

  Wenyi Li;Julien Tailhades;Neil M. O’Brien-Simpson;Frances Separovic

  212
  Citations

• INSL3 as a Biomarker of Leydig Cell Functionality

  Richard Ivell;Richard Ivell;John Desmond Wade;Ravinder Anand-Ivell

  195
  Citations

• Design and development of a peptide-based adiponectin receptor agonist for cancer treatment

  Laszlo Otvos;Eva Haspinger;Eva Haspinger;Francesca La Russa;Francesca La Russa;Federica Maspero;Federica Maspero

  193
  Citations

• DBU as an N alpha-deprotecting reagent for the fluorenylmethoxycarbonyl group in continuous flow solid-phase peptide synthesis.

  J D Wade;J Bedford;R C Sheppard;G W Tregear

  192
  Citations

• Alzheimer disease β-amyloid activity mimics cholesterol oxidase

  Luigi Puglielli;Avi L. Friedlich;Kenneth D.R. Setchell;Seiichi Nagano

  166
  Citations

• Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.

  Ross A. D. Bathgate;Feng Lin;Nicola F. Hanson;Laszlo Otvos

  165
  Citations

• Modulation of hippocampal theta oscillations and spatial memory by relaxin-3 neurons of the nucleus incertus.

  Sherie Ma;Francisco E. Olucha-Bordonau;M. Akhter Hossain;Feng Lin

  165
  Citations

• Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions.

  Seong-Cheol Park;Mi-Hyun Kim;Mohammed Akhter Hossain;Song Yub Shin

  154
  Citations

• R3(BΔ23–27)R/I5 Chimeric Peptide, a Selective Antagonist for GPCR135 and GPCR142 over Relaxin Receptor LGR7: IN VITRO AND IN VIVO CHARACTERIZATION*

  Chester Kuei;Steven Sutton;Pascal Bonaventure;Cindy Pudiak

  153
  Citations

• Peptide thioester preparation by Fmoc solid phase peptide synthesis for use in native chemical ligation

  Andrew B. Clippingdale;Colin J. Barrow;John D. Wade

  149
  Citations