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Chrishan S. Samuel

Chrishan S. Samuel

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
12298
World Ranking
9832
National Ranking
262

Overview

Chrishan S. Samuel is affiliated with Monash University in Australia. Their research principally falls within the field of Medicine, with a focus on several subfields including Public Health, Environmental and Occupational Health, Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Surgery, and Immunology. The breadth of these areas emphasizes an interdisciplinary approach to medical and health sciences.

Their work covers a range of topics such as Pregnancy-related medical research, Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Injury Epidemiology and Prevention, Pulmonary Hypertension Research and Treatments, Renin-Angiotensin System Studies, Pregnancy and preeclampsia studies, and Birth, Development, and Health. This range of topics reflects a consistent emphasis on conditions related to pulmonary and cardiovascular health as well as pregnancy-associated conditions.

Chrishan S. Samuel has contributed to publications in multiple venues. Frequent publication outlets include Biomedicine & Pharmacotherapy, International Journal of Molecular Sciences, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, British Journal of Pharmacology, and Biochemical Pharmacology.

The scientist's recent papers demonstrate engagement with topics such as inflammasomes, cardiovascular fibrosis, atrial fibrillation, obesity, and macrophage biology. Selected publications include:

  • Targeting the NLRP3 inflammasome to treat cardiovascular fibrosis, 2020, Pharmacology & Therapeutics
  • Atrial Fibrillation and Obesity, 2021, JACC. Clinical electrophysiology
  • Inflammasomes-A Molecular Link for Altered Immunoregulation and Inflammation Mediated Vascular Dysfunction in Preeclampsia, 2020, International Journal of Molecular Sciences
  • IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages, 2023, Scientific Reports
  • Relaxin Can Mediate Its Anti-Fibrotic Effects by Targeting the Myofibroblast NLRP3 Inflammasome at the Level of Caspase-1, 2020, Frontiers in Pharmacology

Collaborative work features frequent co-authors including Robert E. Widdop, Amlan Chakraborty, Sharon D. Ricardo, Anita A. Pinar, and Chao Wang. These collaborations indicate a network focused on cardiovascular and immunological research areas, as reflected in the topics and venues of publications.

Best Publications

  • Human Umbilical Cord Mesenchymal Stem Cells Reduce Fibrosis of Bleomycin-Induced Lung Injury

    Yuben Moodley;Daniel Atienza;Ursula Chandini Manuelpillai;Chrishan S Samuel

  • Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene. Novel members of the relaxin peptide family.

    Ross A.D. Bathgate;Chrishan S. Samuel;Tanya C.D. Burazin;Sharon Layfield

  • Electrophysiological, electroanatomical, and structural remodeling of the atria as consequences of sustained obesity

    Rajiv Mahajan;Dennis H. Lau;Anthony G. Brooks;Nicholas J. Shipp

  • Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo

    Chrishan S. Samuel;Elaine N. Unemori;Ishanee Mookerjee;Ross A.D. Bathgate

  • Reduced Nephron Number in Adult Sheep, Hypertensive as a Result of Prenatal Glucocorticoid Treatment

    Elvie Marelyn Wintour;Elvie Marelyn Wintour;Karen Margaret Moritz;Karen Margaret Moritz;K Johnson;Sharon D Ricardo

  • Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension

    Shalini M Krishnan;Yeong H Ling;Brooke M Huuskes;Dorota M Ferens

  • Human Amnion Epithelial Cell Transplantation Abrogates Lung Fibrosis and Augments Repair

    Yuben Moodley;Sivagami Ilancheran;Chrishan Samuel;Vijesh Vaghjiani

  • Relaxin Reverses Cardiac and Renal Fibrosis in Spontaneously Hypertensive Rats

    Edna D. Lekgabe;Helen Kiriazis;Chongxin Zhao;Qi Xu

  • Atrial electrical and structural abnormalities in an ovine model of chronic blood pressure elevation after prenatal corticosteroid exposure: implications for development of atrial fibrillation

    Peter M Kistler;Prashanthan Sanders;Miodrag Dodic;Steven J Spence

  • Obligatory Role for B Cells in the Development of Angiotensin II–Dependent Hypertension

    Christopher Te-Lee Chan;Christopher G Sobey;Maggie Lieu;Dorota M Ferens

  • Relaxin deficiency in mice is associated with an age-related progression of pulmonary fibrosis

    Chrishan S Samuel;Chongxin Zhao;Ross A D Bathgate;Courtney Peta Bond

  • Cardiovascular effects of relaxin: from basic science to clinical therapy

    Xiao-Jun Du;Ross A D Bathgate;Chrishan S Samuel;Anthony M Dart

  • Transplantation of Human Amnion Epithelial Cells Reduces Hepatic Fibrosis in Immunocompetent CCl4-Treated Mice:

    Ursula Manuelpillai;Jorge Tchongue;Dinushka Lourensz;Vijesh Vaghjiani

  • Comparison of airway remodeling in acute, subacute, and chronic models of allergic airways disease.

    Natasha R. Locke;Simon G. Royce;Jacquetta S. Wainewright;Chrishan S. Samuel

  • Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice.

    S M Krishnan;J K Dowling;Y H Ling;H Diep

  • Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice: a gender-specific phenotype.

    Xiao Jun Du;Chrishan S. Samuel;Xiao Ming Gao;Ling Zhao

  • Renal Structural and Functional Repair in a Mouse Model of Reversal of Ureteral Obstruction

    Anita Louise Cochrane;Michelle Monica Kett;Chrishan S Samuel;Naomi V Campanale

  • The Effect of Relaxin on Collagen Metabolism in the Nonpregnant Rat Pubic Symphysis: The Influence of Estrogen and Progesterone in Regulating Relaxin Activity*

    Chrishan S. Samuel;Aldonna Butkus;John P. Coghlan;John F. Bateman

  • Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.

    Ross A. D. Bathgate;Feng Lin;Nicola F. Hanson;Laszlo Otvos

  • Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses.

    Maliha A. Alikhan;Christina V. Jones;Timothy M. Williams;Anthony G. Beckhouse

Frequent Co-Authors

Ross A. D. Bathgate
Ross A. D. Bathgate Florey Institute of Neuroscience and Mental Health
Geoffrey W. Tregear
Geoffrey W. Tregear University of Melbourne
John D. Wade
John D. Wade Florey Institute of Neuroscience and Mental Health
Roger J. Summers
Roger J. Summers Monash University
Mimi L.K. Tang
Mimi L.K. Tang Royal Children's Hospital
Grant R. Drummond
Grant R. Drummond La Trobe University
Andrew L. Gundlach
Andrew L. Gundlach Florey Institute of Neuroscience and Mental Health
Christopher G. Sobey
Christopher G. Sobey La Trobe University
Prashanthan Sanders
Prashanthan Sanders University of Adelaide
Frances Separovic
Frances Separovic University of Melbourne

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