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Germaine Fuh

Germaine Fuh

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
15893
World Ranking
12990
National Ranking
5539

Overview

Germaine Fuh is affiliated with Genentech in the United States and has a research focus spanning medicine, immunology and microbiology, as well as biochemistry, genetics, and molecular biology. Their published work addresses various subjects, including immune cell function, monoclonal and polyclonal antibodies, CAR-T cell therapy, glycosylation and glycoproteins, retinal diseases, and advanced glycation end products.

Their main areas of study include:

  • Immunology
  • Oncology
  • Radiology, Nuclear Medicine and Imaging
  • Molecular Biology
  • Ophthalmology

Fuh has collaborated frequently with several researchers, including Dina Ayupova, Patrick Koenig, Danielle Kellar, Clifford Hom, and Caroline Bonnans. These collaborations have been reflected across multiple publications and projects.

Publication venues where Fuh has contributed work include:

  • Cancer Research
  • Translational Vision Science & Technology
  • Pharmacology Research & Perspectives
  • mAbs
  • Cancer Research Communications

Selected recent publications by Germaine Fuh encompass the following:

  • "Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema," 2022, Translational Vision Science & Technology
  • "Complex formation of anti-VEGF-C with VEGF-C released during blood coagulation resulted in an artifact in its serum pharmacokinetics," 2020, Pharmacology Research & Perspectives
  • "CD200R1 immune checkpoint blockade by the first-in-human anti-CD200R1 antibody 23ME-00610: molecular mechanism and engineering of a surrogate antibody," 2024, mAbs
  • "23ME-01473, an Fc Effector-Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell-Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation," 2025, Cancer Research Communications
  • "Abstract 602: 23ME-00610 is a first-in-class monoclonal antibody that targets the CD200R1 immune checkpoint to enhance T cell-mediated antitumor activity," 2022, Cancer Research

Best Publications

  • Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.

    Y. Chen;C. Wiesmann;G. Fuh;Bing Li

  • Tumor refractoriness to anti-VEGF treatment is mediated by CD11b + Gr1 + myeloid cells

    Farbod Shojaei;Xiumin Wu;Ajay K Malik;Cuiling Zhong

  • Rational design of potent antagonists to the human growth hormone receptor.

    Germaine Fuh;Brian C. Cunningham;Rikiro Fukunaga;Shigekazu Nagata

  • Crystal Structure at 1.7 Å Resolution of VEGF in Complex with Domain 2 of the Flt-1 Receptor

    Christian Wiesmann;Germaine Fuh;Hans W. Christinger;Charles Eigenbrot

  • High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold.

    Chingwei V Lee;Wei-Ching Liang;Mark S Dennis;Charles Eigenbrot

  • Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.

    S.G. Hymowitz;H.W. Christinger;G. Fuh;M.H. Ultsch

  • Synthetic antibody phage libraries

    Germaine G. Fuh;Sachdev S. Sidhu

  • Long-acting Growth Hormones Produced by Conjugation with Polyethylene Glycol

    Ross Clark;Kenneth Olson;Germaine Fuh;Melinda Marian

  • Anti-vegf antibodies

    Germaine Fuh;Hans-Peter Gerber;Wei-Ching Liang;Frederic A. Fellouse

  • Variants of the Antibody Herceptin That Interact with HER2 and VEGF at the Antigen Binding Site

    Jenny Bostrom;Shang-Fan Yu;David Kan;Brent A. Appleton

  • Cross-species Vascular Endothelial Growth Factor (VEGF)-blocking Antibodies Completely Inhibit the Growth of Human Tumor Xenografts and Measure the Contribution of Stromal VEGF

    Wei-Ching Liang;Xiumin Wu;Franklin V. Peale;Chingwei V. Lee

  • VEGF‐null cells require PDGFR α signaling‐mediated stromal fibroblast recruitment for tumorigenesis

    Jianying Dong;Jeremy Grunstein;Max Tejada;Frank Peale

  • Requirements for Binding and Signaling of the Kinase Domain Receptor for Vascular Endothelial Growth Factor

    Germaine Fuh;Bing Li;Craig Crowley;Brian Cunningham

  • The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1.

    Germaine Fuh;K. Christopher Garcia;Abraham M. de Vos

  • A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.

    Gabriele Schaefer;Lauric J. Haber;Lisa M. Crocker;Steven Shia

  • Zinc mediation of the binding of human growth hormone to the human prolactin receptor

    Brian C. Cunningham;Steven Bass;Germaine Fuh;James A. Wells

  • Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions.

    Sachdev S. Sidhu;Bing Li;Yvonne Chen;Frederic A. Fellouse

  • Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models

    Mallika Singh;Anthony Lima;Rafael Molina;Patricia Hamilton

  • Bivalent antibody phage display mimics natural immunoglobulin

    Chingwei V. Lee;Sachdev S. Sidhu;Germaine Fuh

  • Interaction between bevacizumab and murine VEGF-A: a reassessment.

    Lanlan Yu;Xiumin Wu;Zhiyong Cheng;Chingwei V Lee

Frequent Co-Authors

James A. Wells
James A. Wells University of California, San Francisco
Hans-Peter Gerber
Hans-Peter Gerber Seattle Genetics (United States)
Sachdev S. Sidhu
Sachdev S. Sidhu University of Waterloo
Christian Wiesmann
Christian Wiesmann Novartis (Switzerland)
Napoleone Ferrara
Napoleone Ferrara University of California, San Diego

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